Abstract
Identification of coding regions in DNA sequences remains challenging. Various methods have been proposed, but these are limited by species-dependence and the need for adequate training sets. The elements in DNA coding regions are known to be distributed in a quasi-random way, while those in non-coding regions have typical similar structures. For short sequences, these statistical characteristics cannot be extracted correctly and cannot even be detected. This paper introduces a new way to solve the problem: balanced estimation of diffusion entropy (BEDE).
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Zhang, J., Zhang, W. & Yang, H. In search of coding and non-coding regions of DNA sequences based on balanced estimation of diffusion entropy. J Biol Phys 42, 99–106 (2016). https://doi.org/10.1007/s10867-015-9399-7
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DOI: https://doi.org/10.1007/s10867-015-9399-7