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The effect of process variables on the properties of melt-spun poly(lactic acid) fibres for potential use as scaffold matrix materials

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Abstract

Biodegradable materials in the form of fibres and yarns have attracted increasing attention due to a large surface area and various geometric possibilities in three-dimensional polymeric scaffolds for tissue engineering applications. In this study, poly(lactic acid) fibres were produced by melt spinning and subsequent solid-state drawing in order to serve as matrix materials for fibre-based scaffold architectures. The processing of both monofilament and multifilament fibres as well as draw ratios and temperatures were investigated to analyze the effect of process variables on the properties. Two different polylactides with different molecular weight were studied and characterized in terms of their tensile and thermal properties and morphology. The relevance of fibre formation, solid-state drawing and drawing temperatures was clearly supported by the results, and it was shown that the physical properties, such as crystallinity, mechanical strength and ductility can be controlled largely by the drawing process. The obtained fibres demonstrated great potential to be further processed into biotextiles (woven, knitted, or nonwoven scaffolds) using the textile technologies.

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Acknowledgements

This research was funded in part through a grant by Bo Rydin Foundation, SCA, Sweden and the School of Engineering, University of Borås, Sweden. ConMed™ Linvatec is acknowledged for supplying the PLLA. Haike Hilke and Dr. Dan Åkesson at the University of Borås are especially acknowledged for technical support in the measurements.

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Authors and Affiliations

  1. School of Engineering, University of Borås, 501 90, Borås, Sweden

    Maria Persson, Sung-Woo Cho & Mikael Skrifvars

  2. Department of Anatomy and Cell Biology, University of Oulu, 90014, Oulu, Finland

    Maria Persson

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  1. Maria Persson
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  2. Sung-Woo Cho
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  3. Mikael Skrifvars
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Correspondence to Sung-Woo Cho.

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Persson, M., Cho, SW. & Skrifvars, M. The effect of process variables on the properties of melt-spun poly(lactic acid) fibres for potential use as scaffold matrix materials. J Mater Sci 48, 3055–3066 (2013). https://doi.org/10.1007/s10853-012-7022-x

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  • DOI: https://doi.org/10.1007/s10853-012-7022-x

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