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Semen as virus reservoir?

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References

  1. Bausch DG, Towner JS, Dowell SF, Kaducu F, Lukwiya M, Sanchez A, et al. Assessment of the risk of Ebola virus transmission from bodily fluids and fomites. J Infect Dis. 2007;196 Suppl 2:S142–7.

    Article  PubMed  Google Scholar 

  2. Rodriguez LL, De Roo A, Guimard Y, Trappier SG, Sanchez A, Bressler D, et al. Persistence and genetic stability of Ebola virus during the outbreak in Kikwit, Democratic Republic of the Congo, 1995. J Infect Dis. 1999;179 Suppl 1:S170–6.

    Article  CAS  PubMed  Google Scholar 

  3. Emond RT, Evans B, Bowen ET, Lloyd G. A case of Ebola virus infection. Br Med J. 1977;2(6086):541–4.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  4. Cardona-Maya WD, Hernandez PA, Henao DE. Male Ebola survivors: do not forget to use a condom! Reproductive sciences. 2014.

  5. Deen GF, Knust B, Broutet N, Sesay FR, Formenty P, Ross C, et al. Ebola RNA persistence in semen of Ebola virus disease survivors—preliminary report. The New England journal of medicine. 2015.

  6. Mate SE, Kugelman JR, Nyenswah TG, Ladner JT, Wiley MR, Cordier-Lassalle T, et al. Molecular evidence of sexual transmission of Ebola virus. The New England journal of medicine. 2015.

  7. Foy BD, Kobylinski KC, Chilson Foy JL, Blitvich BJ, Travassos da Rosa A, Haddow AD, et al. Probable non-vector-borne transmission of Zika virus, Colorado, USA. Emerg Infect Dis. 2011;17(5):880–2.

    Article  PubMed  PubMed Central  Google Scholar 

  8. McCarthy M. Zika virus was transmitted by sexual contact in Texas, health officials report. BMJ. 2016;352:i720.

    Article  PubMed  Google Scholar 

  9. Musso D, Roche C, Robin E, Nhan T, Teissier A, Cao-Lormeau VM. Potential sexual transmission of Zika virus. Emerg Infect Dis. 2015;21(2):359–61.

    Article  PubMed  PubMed Central  Google Scholar 

  10. Sturmer M, Doerr HW, Berger A, Gute P. Is transmission of HIV-1 in non-viraemic serodiscordant couples possible? Antivir Ther. 2008;13(5):729–32.

    PubMed  Google Scholar 

  11. Lu W, Zeng G, Luo J, Duo S, Xing G, Guo-Wei D, et al. HIV transmission risk among serodiscordant couples: a retrospective study of former plasma donors in Henan, China. J Acquir Immune Defic Syndr. 2010;55(2):232–8.

    Article  PubMed  PubMed Central  Google Scholar 

  12. Houzet L, Matusali G, Dejucq-Rainsford N. Origins of HIV-infected leukocytes and virions in semen. J Infect Dis. 2014;210 Suppl 3:S622–30.

    Article  PubMed  Google Scholar 

  13. Baccetti B, Benedetto A, Burrini AG, Collodel G, Ceccarini EC, Crisa N, et al. HIV-particles in spermatozoa of patients with AIDS and their transfer into the oocyte. J Cell Biol. 1994;127(4):903–14.

    Article  CAS  PubMed  Google Scholar 

  14. Sánchez JA, Cardona-Maya W, Rugeles MT. Implicaciones de la trasmisión del VIH a partir de espermatozoides humanos durante la fecundación. Rev Cuba Obstet Ginecol. 2013;39(3):249–59.

    Google Scholar 

  15. Cardona-Maya W, Velilla PA, Montoya CJ, Cadavid A, Rugeles MT. In vitro human immunodeficiency virus and sperm cell interaction mediated by the mannose receptor. J Reprod Immunol. 2011;92(1–2):1–7.

    Article  CAS  PubMed  Google Scholar 

  16. Cardona Maya W, Rugeles MT, Cadavid AP. Interaccion entre espermatozoides humanos y el virus de la inmunodeficiencia humana. Actas Urol Esp. 2009;33(3):223–6.

    Article  PubMed  Google Scholar 

  17. Cardona-Maya W, Lopez-Herrera A, Velilla-Hernandez P, Rugeles MT, Cadavid AP. The role of mannose receptor on HIV-1 entry into human spermatozoa. Am J Reprod Immunol. 2006;55(4):241–5.

    Article  CAS  PubMed  Google Scholar 

  18. Ceballos A, Lenicov FR, Sabatté J, Rodrígues CR, Cabrini M, Jancic C, et al. Spermatozoa capture HIV-1 through heparan sulfate and efficiently transmit the virus to dendritic cells. J Exp Med. 2009;206(12):2717–33.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  19. Christianson HC, Belting M. Heparan sulfate proteoglycan as a cell-surface endocytosis receptor. Matrix Biol. 2014;35:51–5.

    Article  CAS  PubMed  Google Scholar 

  20. Bagasra O, Farzadegan H, Seshamma T, Oakes JW, Saah A, Pomerantz RJ. Detection of HIV-1 proviral DNA in sperm from HIV-1-infected men. Aids. 1994;8(12):1669–74.

    Article  CAS  PubMed  Google Scholar 

  21. Nuovo GJ, Becker J, Simsir A, Margiotta M, Khalife G, Shevchuk M. HIV-1 nucleic acids localize to the spermatogonia and their progeny. A study by polymerase chain reaction in situ hybridization. Am J Pathol. 1994;144(6):1142–8.

    CAS  PubMed  PubMed Central  Google Scholar 

  22. Cardona-Maya W, Velilla P, Montoya CJ, Cadavid A, Rugeles MT. Presence of HIV-1 DNA in spermatozoa from HIV-positive patients: changes in the semen parameters. Curr HIV Res. 2009;7(4):418–24.

    Article  CAS  PubMed  Google Scholar 

  23. Zea-Mazo JW, Negrette-Mejia YA, Cardona-Maya W. Virus of sexual transmission: semen and virus relationship. Actas Urol Esp. 2010;34(10):845–53.

    Article  CAS  PubMed  Google Scholar 

  24. McCarthy M. Couples at risk from exposure to Zika virus should consider delaying pregnancy, says CDC. BMJ (Clinical research ed). 2016;352:i1813.

  25. Rowland A, Washington CI, Sheffield JS, Pardo-Villamizar CA, Segars JH. Zika virus infection in semen: a call to action and research. J Assist Reprod Genet. 2016;33(4):435–7.

    Article  PubMed  Google Scholar 

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Correspondence to Walter D. Cardona Maya.

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Cardona Maya, W.D., Du Plessis, S.S. & Velilla, P.A. Semen as virus reservoir?. J Assist Reprod Genet 33, 1255–1256 (2016). https://doi.org/10.1007/s10815-016-0747-8

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  • DOI: https://doi.org/10.1007/s10815-016-0747-8

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