Oocyte retrieval following continued stimulation five days beyond ovulation yields live birth after frozen embryo transfer
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There is often a narrow time window for cancer patients to accomplish fertility preservation before cancer treatment initiation. Despite attempts at pituitary blockade, premature ovulation prior to oocyte retrieval may occur. In that situation, conventional practice dictates cancellation of the cycle. There is no existing literature regarding oocyte quality and yield in stimulated cycles in which ovulation occurs in the early follicular phase prior to hCG trigger. Here we report a case of continued ovarian stimulation 3 days beyond documented ovulation in a woman with breast cancer, with the cycle yielding embryos capable of resulting in a successful twin pregnancy after transfer to a gestational surrogate.
A 40-year-old gravida1 para 0 who had recently undergone bilateral mastectomy for invasive ductal carcinoma desired fertility preservation prior to chemotherapy and prophylactic bilateral salpingo-oophorectomy. She planned to take adjuvant hormonal therapy for ...
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- Oocyte retrieval following continued stimulation five days beyond ovulation yields live birth after frozen embryo transfer
Journal of Assisted Reproduction and Genetics
Volume 29, Issue 5 , pp 433-435
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- 1. Stanford Fertility and Reproductive Medicine Center, 900 Welch Road, Suite 350, Palo Alto, CA, 94305, USA
- 3. Stanford Fertility and Reproductive Medicine Center, 900 Welch Road, Suite 350, Palo Alto, CA, 94304, USA
- 2. Department of Obstetrics and Gynecology, Stanford University Medical Center, 300 Pasteur Road, Palo Alto, CA, 94305, USA