Journal of Autism and Developmental Disorders

, Volume 43, Issue 9, pp 2159–2173

Feeding Problems and Nutrient Intake in Children with Autism Spectrum Disorders: A Meta-analysis and Comprehensive Review of the Literature

  • William G. Sharp
  • Rashelle C. Berry
  • Courtney McCracken
  • Nadrat N. Nuhu
  • Elizabeth Marvel
  • Celine A. Saulnier
  • Ami Klin
  • Warren Jones
  • David L. Jaquess
Original Paper

DOI: 10.1007/s10803-013-1771-5

Cite this article as:
Sharp, W.G., Berry, R.C., McCracken, C. et al. J Autism Dev Disord (2013) 43: 2159. doi:10.1007/s10803-013-1771-5

Abstract

We conducted a comprehensive review and meta-analysis of research regarding feeding problems and nutrient status among children with autism spectrum disorders (ASD). The systematic search yielded 17 prospective studies involving a comparison group. Using rigorous meta-analysis techniques, we calculated the standardized mean difference (SMD) with standard error and corresponding odds ratio (OR) with 95 % confidence intervals (CI). Results indicated children with ASD experienced significantly more feeding problems versus peers, with an overall SMD of 0.89 (0.08) and a corresponding OR of 5.11, 95 % CI 3.74–6.97. Nutrient analyses indicated significantly lower intake of calcium (SMD: −0.65 [0.29]; OR: 0.31, 95 % CI 0.11–0.85) and protein (SMD: −0.58 [0.25]; OR: 0.35, 95 % CI: 0.14–0.56) in ASD. Future research must address critical questions regarding the cause, long-term impact, and remediation of atypical feeding in this population.

Keywords

DietFood selectivityMealtime problemsNutritionPicky eatingPediatric feeding disorders

Copyright information

© Springer Science+Business Media New York 2013

Authors and Affiliations

  • William G. Sharp
    • 1
    • 2
  • Rashelle C. Berry
    • 2
  • Courtney McCracken
    • 1
  • Nadrat N. Nuhu
    • 2
  • Elizabeth Marvel
    • 2
  • Celine A. Saulnier
    • 1
    • 2
  • Ami Klin
    • 1
    • 2
  • Warren Jones
    • 1
    • 2
  • David L. Jaquess
    • 1
    • 2
  1. 1.Department of PediatricsEmory University School of MedicineAtlantaUSA
  2. 2.The Marcus Autism CenterAtlantaUSA