Journal of Autism and Developmental Disorders

, Volume 43, Issue 1, pp 188–199

Eye-Tracking, Autonomic, and Electrophysiological Correlates of Emotional Face Processing in Adolescents with Autism Spectrum Disorder

  • Jennifer B. Wagner
  • Suzanna B. Hirsch
  • Vanessa K. Vogel-Farley
  • Elizabeth Redcay
  • Charles A. Nelson
Original Paper

DOI: 10.1007/s10803-012-1565-1

Cite this article as:
Wagner, J.B., Hirsch, S.B., Vogel-Farley, V.K. et al. J Autism Dev Disord (2013) 43: 188. doi:10.1007/s10803-012-1565-1

Abstract

Individuals with autism spectrum disorder (ASD) often have difficulty with social-emotional cues. This study examined the neural, behavioral, and autonomic correlates of emotional face processing in adolescents with ASD and typical development (TD) using eye-tracking and event-related potentials (ERPs) across two different paradigms. Scanning of faces was similar across groups in the first task, but the second task found that face-sensitive ERPs varied with emotional expressions only in TD. Further, ASD showed enhanced neural responding to non-social stimuli. In TD only, attention to eyes during eye-tracking related to faster face-sensitive ERPs in a separate task; in ASD, a significant positive association was found between autonomic activity and attention to mouths. Overall, ASD showed an atypical pattern of emotional face processing, with reduced neural differentiation between emotions and a reduced relationship between gaze behavior and neural processing of faces.

Keywords

Autism spectrum disorderEye-trackingEvent-related potentialsPupillometryEmotional face processing

Copyright information

© Springer Science+Business Media, LLC 2012

Authors and Affiliations

  • Jennifer B. Wagner
    • 1
    • 2
  • Suzanna B. Hirsch
    • 1
  • Vanessa K. Vogel-Farley
    • 1
  • Elizabeth Redcay
    • 3
  • Charles A. Nelson
    • 1
    • 2
  1. 1.Laboratories of Cognitive Neuroscience, Division of Developmental MedicineChildren’s Hospital BostonBostonUSA
  2. 2.Harvard Medical SchoolBostonUSA
  3. 3.Department of PsychologyUniversity of MarylandCollege ParkUSA