Original Paper

Journal of Autism and Developmental Disorders

, Volume 38, Issue 5, pp 827-839

The Modified Checklist for Autism in Toddlers: A Follow-up Study Investigating the Early Detection of Autism Spectrum Disorders

  • Jamie M. KleinmanAffiliated withDepartment of Psychology, University of Connecticut Email author 
  • , Diana L. RobinsAffiliated withGeorgia State University
  • , Pamela E. VentolaAffiliated withYale University School of Medicine
  • , Juhi PandeyAffiliated withDepartment of Psychology, University of Connecticut
  • , Hilary C. BoorsteinAffiliated withDepartment of Psychology, University of Connecticut
  • , Emma L. EsserAffiliated withDepartment of Psychology, University of Connecticut
  • , Leandra B. WilsonAffiliated withDepartment of Psychology, University of Connecticut
  • , Michael A. RosenthalAffiliated withDepartment of Psychology, University of Connecticut
  • , Saasha SuteraAffiliated withDepartment of Psychology, University of Connecticut
    • , Alyssa D. VerbalisAffiliated withDepartment of Psychology, University of Connecticut
    • , Marianne BartonAffiliated withDepartment of Psychology, University of Connecticut
    • , Sarah HodgsonAffiliated withDepartment of Psychology, University of Connecticut
    • , James GreenAffiliated withDepartment of Psychology, University of Connecticut
    • , Thyde Dumont-MathieuAffiliated withDepartment of Psychology, University of Connecticut
    • , Fred VolkmarAffiliated withYale University School of Medicine
    • , Katarzyna ChawarskaAffiliated withYale University School of Medicine
    • , Ami KlinAffiliated withYale University School of Medicine
    • , Deborah FeinAffiliated withDepartment of Psychology, University of Connecticut

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Abstract

Autism spectrum disorders (ASD) often go undetected in toddlers. The Modified Checklist for Autism in Toddlers (M-CHAT) was used to screen 3,793 children aged 16–30 months from low- and high-risk sources; screen positive cases were diagnostically evaluated. Re-screening was performed on 1,416 children aged 42–54 months. Time1 Positive Predictive Value (PPV) was .36 for the initial screening and .74 for the screening plus follow-up telephone interview; values were similar for Time2 PPV. When separating referral sources, PPV was low for the low-risk sample but acceptable with the follow-up telephone interview. Children with ASD from the low-risk and high-risk samples were highly similar. Results indicate that the M-CHAT continues to be a promising instrument for the early detection of ASD.

Keywords

Autism Early identification Pediatric screening