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Transepithelial phototherapeutic keratectomy for the treatment of severe band keratopathy

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Abstract

Purpose

The goal of this study was to investigate the clinical outcomes of transepithelial phototherapeutic keratectomy (transepithelial PTK) for the treatment of severe band keratopathy.

Methods

A consecutive series of severe band keratopathy cases treated with transepithelial PTK were retrospectively analysed between January 2018 and December 2019. Severe band keratopathy was defined as corneal plaques apparent in the obscuration of iris details. Patients’ medical histories, preoperative and postoperative symptomatic relief, cosmesis, best-corrected visual acuity (BCVA), complications, and recurrences were analysed.

Results

Seventeen eyes of 16 patients were included in the study, with a mean follow-up of 9.8 ± 5.2 months (3 to 19 months). The mean age of the patients was 15.8 ± 10.2 years (8 to 46 years). Symptoms were significantly or completely relieved in all patients (100%). The results of cosmesis were good in 14 eyes (82.4%). Among those eyes that had BCVA of hand motion or better preoperatively, seven eyes (100%) showed an improvement in BCVA postoperatively. There were no complications or recurrences associated with transepithelial PTK treatment during the follow-up period.

Conclusions

Transepithelial PTK is an effective treatment to eliminate corneal opacity and alleviate symptoms in patients with severe band keratopathy. This technique could be an alternative approach to managing severe band keratopathy.

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Availability of data and material

All data generated or analysed during this study are included in this manuscript.

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Funding

No funding was acquired to conduct the research.

Author information

Authors and Affiliations

  1. Department of Ophthalmology, Shanghai Tenth People’s Hospital, Tongji University School of Medicine, Shanghai, China

    Yiyong Qian

  2. Department of Ophthalmology, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, 1665 Kongjiang Rd, Shanghai, 200092, People’s Republic of China

    Peiquan Zhao, Haiyan Li & Hehua Ye

Authors
  1. Yiyong Qian
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  2. Peiquan Zhao
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  3. Haiyan Li
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  4. Hehua Ye
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Contributions

All authors contributed to the study conception and design. Material preparation, data collection, and analysis were performed by YQ, PZ, HL, and HY. The first draft of the manuscript was written by Yiyong Qian, and all authors commented on previous versions of the manuscript. All authors read and approved the final manuscript.

Corresponding author

Correspondence to Hehua Ye.

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Conflict of interest

The authors declare that they have no conflict of interest.

Ethics approval

Ethical approval was waived by the Ethics Committee of Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine in view of the retrospective nature of the study, and all the procedures being performed were part of the routine care. The study followed the guidelines in the Declaration of Helsinki.

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Informed written consent was obtained from all study participants or their parents.

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Patients signed informed consent regarding publishing their data and photographs.

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Qian, Y., Zhao, P., Li, H. et al. Transepithelial phototherapeutic keratectomy for the treatment of severe band keratopathy. Int Ophthalmol 40, 2469–2474 (2020). https://doi.org/10.1007/s10792-020-01574-3

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  • DOI: https://doi.org/10.1007/s10792-020-01574-3

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