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A case study of ciliary detachment with primary pulmonary hypertension

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Abstract

Purpose

To introduce a case of ciliary detachment with primary pulmonary hypertension (PPH).

Methods

The clinical manifestations of a case of ciliary detachment with PPH were addressed by comprehensive examination including ultrasound biological microscope (UBM), intraocular pressure, color fundus photographs, fluorescence fundus angiography (FFA). In addition, echocardiography is used to measure primary pulmonary pressure.

Results

When the echocardiography displayed a systolic pulmonary arterial pressure of 106 mmHg, UBM exhibited ciliochoroidal detachment, as well as peripheral retinal effusion and non-perfusion areas in FFA. After well controlled of PPH, UBM showed normal ciliary body. FFA confirmed that retinal effusion disappeared.

Conclusions

The elevated venous pressure in PPH is responsible for decreased choroidal backflow and reduced venous blood outflow from the eye. PPH would contribute to the clinical manifestations of severe choroidal detachment and peripheral retina effusion in this patient.

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References

  1. Marushak DANU (1982) Uveal effusion attending scleritis posterior. Acta Ophthalmol 60:773–778

    Article  CAS  Google Scholar 

  2. Akduman L, Del Priore LV, Kaplan HJ, Meredith T (1996) Uveal effusion syndrome associated with primary pulmonary hypertension and vomiting. Am J Ophthalmol 121:578–580. doi:10.1016/S0002-9394(14)75439-X

    Article  CAS  PubMed  Google Scholar 

  3. Gislason I, Jonasson F, Stefansson E (1991) Exudative retinal detachment in familial pulmonary hypertension. Acta Ophthalmol 69:805–809

    Article  CAS  Google Scholar 

  4. Martiano D, Chevreaud O, Lam D, Cohen SY, Souied EH (2016) Acute serous retinal detachment in idiopathic pulmonary arterial hypertension. Retin Cases Brief Rep. doi:10.1097/ICB.0000000000000336

    Google Scholar 

  5. Li XQ, Pryds A, Carlsen J, Larsen M (2015) Multifocal central serous chorioretinopathy with photoreceptor-retinal pigment epithelium diastasis in heritable pulmonary arterial hypertension. Retin Cases Brief Rep 9(1):83–87

    Article  PubMed  Google Scholar 

  6. Khan MA, Ho AC, Spirn MJ (2017) Cotton-wool spots after use of Macitentan for pulmonary arterial hypertension. Retin Cases Brief Rep 11(1):4–6. doi:10.1097/ICB.0000000000000273

    Article  PubMed  Google Scholar 

  7. Matsubara H, Ogawa A (2014) Treatment of idiopathic/hereditary pulmonary arterial hypertension. J Cardiol 64:243–249

    Article  PubMed  Google Scholar 

  8. Sanchez-Sevila JL, Martinez-Rubio M, Lopez-Meca I, Belmonte-Martinez J (2013) Exudative retinal detachment and primary pulmonary hypertension. Archivos de la Sociedad Española de Oftalmología 88:189–192

    Article  CAS  PubMed  Google Scholar 

  9. Saran BR, Brucker AJ, Bandello F, Verougstraete C (2001) Familial primary pulmonary hypertension and associated ocular findings. Retina 21:34–39

    Article  CAS  PubMed  Google Scholar 

Download references

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Author notes

    Authors and Affiliations

    1. Key Laboratory of Harbin Medical University Eye Center in Eye Hospital, The First Affiliated Hospital of Harbin Medical University, 23 Youzheng Street, Nangang District, Harbin, Heilongjiang Province, 150001, People’s Republic of China

      Zhuolei Feng, Li Dong, Jie Bai, Ming-Ming Yang & Yi Zheng

    2. Cardiovascular Division, The First Affiliated Hospital of Harbin Medical University, 23 Youzheng Street, Nangang District, Harbin, Heilongjiang Province, 150001, People’s Republic of China

      Junxian Cao

    3. Department of Pharmacology, New York Medical College, 15 Dana Road, Valhalla, NY, 10595, USA

      Daohong Lin

    Authors
    1. Zhuolei Feng
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    2. Li Dong
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    3. Junxian Cao
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    4. Jie Bai
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    5. Ming-Ming Yang
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    6. Yi Zheng
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    7. Daohong Lin
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    Corresponding authors

    Correspondence to Li Dong or Daohong Lin.

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    Conflict of interest

    No potential conflicts of interest relevant to this article are declared.

    Additional information

    Zhuolei Feng and Li Dong have contributed equally to this work.

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    Cite this article

    Feng, Z., Dong, L., Cao, J. et al. A case study of ciliary detachment with primary pulmonary hypertension. Int Ophthalmol 38, 375–379 (2018). https://doi.org/10.1007/s10792-017-0443-4

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    • DOI: https://doi.org/10.1007/s10792-017-0443-4

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