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Microbes as trigger/sustainers of chronic immuno-mediated inflammatory diseases

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Notes

  1. This term ‘auto-intolerant’ is used rather than the conventional but quite misleading term ‘auto-immune’. A little reflection shows the body is far from immune (ie protected) but may often be ravaged by the misdirected immune defences. The pharmacological focus then shifts from overall immunosuppression, a high-risk strategy, to either a low-risk selective re-education of the immune system (→tolerance) or better still, to controlling (perhaps eliminating) the agents initially provoking this loss of tolerance.

  2. Including those based on inexpensive nutritional supplements, e.g., ascorbic acid, copper and zinc to promote connective tissue repair and wound healing.

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Authors and Affiliations

  1. Schools of Medicine (Gold Coast Campus) and Natural Sciences (Nathan Campus), Griffith University, Brisbane, QLD, 4111, Australia

    Michael W. Whitehouse

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  1. Michael W. Whitehouse
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Correspondence to Michael W. Whitehouse.

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Dedicated to the memory of Barry Marmion AO (1920–2014) of Edinburgh, Scotland and Adelaide, Australia, virologist and pioneer of a vaccine for “Q fever” (a potentially lethal human infection caused by a rickettsial bacterium Coxiella burnetii carried by cattle and goats).

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Whitehouse, M.W. Microbes as trigger/sustainers of chronic immuno-mediated inflammatory diseases. Inflammopharmacol 23, 371–374 (2015). https://doi.org/10.1007/s10787-015-0244-1

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