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Chronic thromboembolic pulmonary hypertension: detection, medical and surgical treatment approach, and current outcomes

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Abstract

Pulmonary hypertension due to chronic thromboembolic disease is potentially curable with pulmonary thromboendarterectomy surgery. As a result, it is important for clinicians to recognize and appropriately diagnose this form of pulmonary hypertension. Advances in this field with changes in surgical technique, the availability of PH-targeted medical therapy for select patient subgroups, and the development of balloon pulmonary angioplasty have broadened therapeutic options for patients. This review will examine what is known about the epidemiology and medical conditions placing patients at risk of developing this disease, will present an approach to evaluation of patients with suspected chronic thromboembolic disease, and will describe the surgical and non-surgical management of this unique patient population.

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    1. Division of Pulmonary, Critical Care and Sleep Medicine, University of California, San Diego Healthcare, 9300 Campus Point Drive, La Jolla, CA, 92037, USA

      David S. Poch & William R. Auger

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    Correspondence to David S. Poch.

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    Dr. David Poch has served as a speaker on behalf of Bayer Pharmaceuticals.

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    Drs. David S. Poch and William R. Auger have contributed equally to this article.

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    Poch, D.S., Auger, W.R. Chronic thromboembolic pulmonary hypertension: detection, medical and surgical treatment approach, and current outcomes. Heart Fail Rev 21, 309–322 (2016). https://doi.org/10.1007/s10741-015-9518-3

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