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Early Modern Experimentation on Live Animals

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Abstract

Starting from the works by Aselli (De lactibus sive lacteis venis, 1627) on the milky veins and Harvey (1628, translated in 1993) on the motion of the heart and the circulation of the blood, the practice of vivisection witnessed a resurgence in the early modern period. I discuss some of the most notable cases in the century spanning from Aselli’s work to the investigations of fluid pressure in plants and animals by Stephen Hales (Vegetable Staticks, 1727). Key figures in my study include Johannes Walaeus, Jean Pecquet, Marcello Malpighi, Reinier de Graaf, Richard Lower, Anton Nuck, and Anton de Heide. Although vivisection dates from antiquity, early modern experimenters expanded the range of practices and epistemic motivations associated with it, displaying considerable technical skills and methodological awareness about the problems associated with the animals being alive and the issue of generalizing results to humans. Many practitioners expressed great discomfort at the suffering of the animals; however, many remained convinced that their investigations were not only indispensable from an epistemic standpoint but also had potential medical applications. Early modern vivisection experiments were both extensive and sophisticated and cannot be ignored in the literature of early modern experimentation or of experimentation on living organisms across time.

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Correspondence to Domenico Bertoloni Meli.

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Previous versions of this essay were delivered at venues on both sides of the Atlantic. I thank Hal Cook, Karin Ekholm, Evan Ragland, Bob Richards, Allen Shotwell, Nancy Siraisi, Fernando Vidal, the anonymous referees, and all those who offered comments on previous versions of my work.

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Bertoloni Meli, D. Early Modern Experimentation on Live Animals. J Hist Biol 46, 199–226 (2013). https://doi.org/10.1007/s10739-012-9327-7

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