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Case report: metachronous central nervous system desmoid tumours and thyroid carcinoma in a young familial adenomatous polyposis patient

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Abstract

We report a familial adenomatous polyposis patient with a known truncating mutation on exon 15 of the APC gene who developed an invasive follicular thyroid cancer in addition to multiple intra-cranial and spinal desmoids. This combination of manifestations has not previously been recorded in the literature.

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Authors and Affiliations

  1. University of New South Wales, Sydney, NSW, Australia

    G. I. Butel-Simoes

  2. University of New South Wales, St Vincent’s Clinic School, St Vincent’s Hospital, Darlinghurst, NSW, Australia

    A. D. Spigelman

  3. St Vincent’s Hereditary Cancer Clinic, The Kinghorn Cancer Centre, St Vincent’s Hospital, Darlinghurst, NSW, Australia

    A. D. Spigelman

  4. Hunter Family Cancer Service, Waratah, NSW, Australia

    A. D. Spigelman

Authors
  1. G. I. Butel-Simoes
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  2. A. D. Spigelman
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Correspondence to A. D. Spigelman.

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Butel-Simoes, G.I., Spigelman, A.D. Case report: metachronous central nervous system desmoid tumours and thyroid carcinoma in a young familial adenomatous polyposis patient. Familial Cancer 12, 647–649 (2013). https://doi.org/10.1007/s10689-013-9640-0

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  • DOI: https://doi.org/10.1007/s10689-013-9640-0

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