Skip to main content

Advertisement

Log in

Time trends of cause-specific mortality among resettlers in Germany, 1990 through 2009

  • MORTALITY
  • Published:
European Journal of Epidemiology Aims and scope Submit manuscript

Abstract

Resettlers (in German: (Spät-)Aussiedler) form one of the biggest migrant groups in Germany. It is known that migrants have different mortality patterns compared to the autochthon population. In this paper, we combined data from three resettler cohorts and examined differences in mortality from non-communicable diseases among resettlers in Germany and the German population. Furthermore, we investigated time trends of cause-specific mortality for 20 years of follow-up and compared it with the German mortality rates. To assess differences in cause-specific mortality between resettlers and the general German population, we calculated standardized mortality ratios (SMRs). To ascertain mortality trends, cause-specific age-standardized mortality rates were calculated and modeled with Poisson regression and fractional polynomials. During the observation period, the study population accumulated almost 800,000 person-years and 5572 deaths were observed. All-cause mortality among resettlers was lower (SMR = 0.91, 95% CI = 0.89–0.94) compared to the general German population, as well as cardiovascular diseases (CVD) mortality (SMR = 0.82, 95% CI = 0.79–0.86). Results for cancer mortality varied considerably by cancer site. Analyses of time trends showed that all-cause and CVD mortality were decreasing over time in resettlers, as well as in the general German population. Lower all-cause mortality among resettlers is mainly explained by lower CVD mortality. Cancer-site specific mortality showed different results. Converging mortality rates may indicate an adaption of lifestyle behavior. However, there are no data on individual risk factors in this study.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2

Similar content being viewed by others

References

  1. Worbs S, Bund E, Kohls M, Babka von Gostomski C. (Spät-) Aussiedler in Deutschland. Eine Analyse aktueller Daten und Forschungsergebnisse. Nürnberg: Bundesamt für Migration und Flüchtlinge; 2013.

    Google Scholar 

  2. Razum O, Wenner J. Social and health epidemiology of immigrants in Germany: past, present and future. Public Health Rev. 2016;37(1):4.

    Article  Google Scholar 

  3. Bray F, Parkin DM. Descriptive Studies. In: Ahrens W, Pigeot I, editors. Handbook of Epidemiology. 2nd ed. New York: Springer; 2014. p. 187–258.

  4. Marmot MG, Syme SL. Acculturation and coronary heart disease in Japanese–Americans. Am J Epidemiol. 1976;104(3):225–47.

    Article  CAS  PubMed  Google Scholar 

  5. Razum O, Zeeb H, Gerhardus A. Cardiovascular mortality of Turkish nationals residing in West Germany. Ann Epidemiol. 1998;8(5):334–41.

    Article  CAS  PubMed  Google Scholar 

  6. Frisbie WP, Cho Y, Hummer RA. Immigration and the health of Asian and Pacific Islander adults in the United States. Am J Epidemiol. 2001;153(4):372–80.

    Article  CAS  PubMed  Google Scholar 

  7. Deckert A, Winkler V, Paltiel A, Razum O, Becher H. Time trends in cardiovascular disease mortality in Russia and Germany from 1980 to 2007-are there migration effects? BMC Public Health. 2010;10(1):1.

    Article  Google Scholar 

  8. Winkler V, Ott JJ, Holleczek B, Stegmaier C, Becher H. Cancer profile of migrants from the Former Soviet Union in Germany: incidence and mortality. Cancer Causes Control. 2009;20(10):1873–9.

    Article  PubMed  Google Scholar 

  9. Kyobutungi C, Ronellenfitsch U, Razum O, Becher H. Mortality from external causes among ethnic German immigrants from former Soviet Union countries, in Germany. Eur J Public Health. 2006;16(4):376–82.

    Article  PubMed  Google Scholar 

  10. Volodina A, Bertsche T, Kostev K, Winkler V, Haefeli WE, Becher H. Drug utilization patterns and reported health status in ethnic German migrants (Aussiedler) in Germany: a cross-sectional study. BMC Public Health. 2011;11(1):1.

    Article  Google Scholar 

  11. Ronellenfitsch U, Kyobutungi C, Becher H, Razum O. All-cause and cardiovascular mortality among ethnic German immigrants from the Former Soviet Union: a cohort study. BMC Public Health. 2006;6(1):1.

    Article  Google Scholar 

  12. Becher H, Razum O, Kyobutungi C, Laki J, Ott JJ, Ronellenfitsch U, et al. Mortalität von Aussiedlern aus der ehemaligen Sowjetunion. Deutsches Aerzteblatt. 2007;104(23):1655–61.

    Google Scholar 

  13. Deckert A, Winkler V, Meisinger C, Heier M, Becher H. Myocardial infarction incidence and ischemic heart disease mortality: overall and trend results in repatriates, Germany. Eur J Public Health. 2014;24(1):127–33.

    Article  PubMed  Google Scholar 

  14. Nichols M, Townsend N, Scarborough P, Rayner M. Cardiovascular disease in Europe: epidemiological update. Eur Heart J. 2013;34(39):3028–34.

    Article  PubMed  Google Scholar 

  15. Ronellenfitsch U, Kyobutungi C, Becher H, Razum O. Large-scale, population-based epidemiological studies with record linkage can be done in Germany. Eur J Epidemiol. 2004;19(12):1073–4.

    Article  PubMed  Google Scholar 

  16. Hammer GP. Makros zur Berechnung von Personenjahren in epidemiologischen Studien. In: Proceedings der 15 Konferenz der SAS-Anwender in Forschung und Entwicklung. 2011; 223–232.

  17. Greenland S, Rothman KJ. Introduction to Stratified Analysis. In: Rothman KJ, Greenland S, Lash TL, editors. Modern Epidemiology. 3rd ed. Philadelphia: Lippincott Williams & Wilkins; 2008. p. 258–82.

    Google Scholar 

  18. World Health Organization. WHO mortality database. 2015. http://www.who.int/healthinfo/mortality_data/en/ Accessed 05 May 2016.

  19. Gaber E, Wildner M. Themenheft 52 “Sterblichkeit, Todesursachen und regionale Unterschiede”. 2011.

  20. Rittgen W, Becker N. SMR Analysis of Historical Follow-Up Studies with Missing Death Certificates. Biometrics. 2000;56(4):1164–9.

    Article  CAS  PubMed  Google Scholar 

  21. Pace M, Lanzieri G, Glickman M, Zupanič T. Revision of the European Standard Population: report of Eurostat’s task force. Publications Office of the European Union; 2013.

  22. Sauerbrei W, Royston P. Building multivariable prognostic and diagnostic models: transformation of the predictors by using fractional polynomials. J R Stat Soc Ser A (Statistics in Society). 1999;162(1):71–94.

    Article  Google Scholar 

  23. Krieger V, Kampen H, Paulsen N, Kopp L, Schleicher J, Kampen J. Deutsche aus Russland gestern und heute: Volk auf dem Weg. Landsmannschaft der Deutschen aus Russland eV.; 2006.

  24. Razum O, Geiger I, Zeeb H, Ronellenfitsch U. Gesundheitsversorgung von Migranten. Dtsch Arztebl. 2004;101(43):43.

    Google Scholar 

  25. Reiss K, Spallek J, Razum O. ‘Imported risk’or’health transition’? Smoking prevalence among ethnic German immigrants from the Former Soviet Union by duration of stay in Germany-analysis of microcensus data. Int J Equity Health. 2010;9(1):15.

    Article  PubMed  PubMed Central  Google Scholar 

  26. Antecol H, Bedard K. Unhealthy assimilation: why do immigrants converge to American health status levels? Demography. 2006;43(2):337–60.

    Article  PubMed  Google Scholar 

  27. Turra CM, Elo IT. The impact of salmon bias on the Hispanic mortality advantage: new evidence from social security data. Popul Res Policy Rev. 2008;27(5):515–30.

    Article  PubMed  PubMed Central  Google Scholar 

  28. Gesellschaft der epidemiologischen Krebsregister in Deutschland. GEKID Atlas—C33–C34 Lungenkrebs Mortalität Männer. 2013. http://www.gekid.de/Atlas/CurrentVersion/atlas.html. Accessed 03 Feb 2017.

  29. Kibele EU. Appendices of Regional mortality differences in Germany. In: Kibele EU, editor. Regional mortality differences in Germany. Springer Science & Business Media; 2012. p. 217-71.

  30. Statistische Ämter des Bundes und der Länder. Zensus 2011—Methoden und Verfahren. Wiesbaden: Statistisches Bundesamt; 2015.

    Google Scholar 

  31. Bundesamt für Migration und Flüchtlinge. Migrationsbericht des Bundesamtes für Migration und Flüchtlinge im Auftrag der Bundesregierung. 2016.

  32. Piepoli MF, Hoes AW, Agewall S, Albus C, Brotons C, Catapano AL et al. 2016 European Guidelines on cardiovascular disease prevention in clinical practice. Eur Heart J. 2016:ehw106.

  33. Kuhrs E, Winkler V, Becher H. Risk factors for cardiovascular and cerebrovascular diseases among ethnic Germans from the former Soviet Union: results of a nested case–control study. BMC Public Health. 2012;12(1):1.

    Article  Google Scholar 

  34. Ganna A, Magnusson PK, Pedersen NL, de Faire U, Reilly M, Ärnlöv J, et al. Multilocus genetic risk scores for coronary heart disease prediction. Arterioscler Thromb Vasc Biol. 2013;33(9):2267–72.

    Article  CAS  PubMed  Google Scholar 

  35. Havulinna AS, Kettunen J, Ukkola O, Osmond C, Eriksson JG, Kesäniemi YA, et al. A blood pressure genetic risk score is a significant predictor of incident cardiovascular events in 32 669 individualsnovelty and significance. Hypertension. 2013;61(5):987–94.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  36. Muka T, Koromani F, Portilla E, O’Connor A, Bramer WM, Troup J, et al. The role of epigenetic modifications in cardiovascular disease: a systematic review. Int J Cardiol. 2016;212:174–83.

    Article  PubMed  Google Scholar 

  37. Andreassi MG. Metabolic syndrome, diabetes and atherosclerosis: influence of gene–environment interaction. Mutat Res/Fundam Mol Mech Mutagen. 2009;667(1):35–43.

    Article  CAS  Google Scholar 

  38. Torre LA, Bray F, Siegel RL, Ferlay J, Lortet-Tieulent J, Jemal A. Global cancer statistics, 2012. CA Cancer J Clin. 2015;65(2):87–108.

    Article  PubMed  Google Scholar 

  39. World Cancer Research Fund International & American Insitute for Cancer Research. Continuous update project report: diet, nutrition, physical activity, and prostate cancer. 2014.

  40. Agudo A, Bonet C, Travier N, González CA, Vineis P, Bueno-de-Mesquita HB, et al. Impact of cigarette smoking on cancer risk in the European prospective investigation into cancer and nutrition study. J Clin Oncol. 2012;30(36):4550–7.

    Article  PubMed  Google Scholar 

  41. Boffetta P, Hashibe M, La VC, Zatonski W, Rehm J. The burden of cancer attributable to alcohol drinking. Int J Cancer. 2006;119(4):884–7.

    Article  CAS  PubMed  Google Scholar 

  42. World Bank. Fertility rate, total (births per woman). 2016. http://data.worldbank.org/indicator/SP.DYN.TFRT.IN?end=2014&start=1990&view=chart. Accessed 10 Aug 2016.

  43. Hirte L, Nolte E, Bain C, McKee M. Breast cancer mortality in Russia and Ukraine 1963–2002: an age-period-cohort analysis. Int J Epidemiol. 2007;36(4):900–6.

    Article  PubMed  Google Scholar 

  44. Aparicio ML, Döring A, Mielck A, Holle R. Unterschiede zwischen Aussiedlern und der übrigen deutschen Bevölkerung bezüglich Gesundheit, Gesundheitsversorgung und Gesundheitsverhalten: eine vergleichende Analyse anhand des KORA-Surveys 2000. Sozial-und Präventivmedizin. 2005;50(2):107–18.

    Article  PubMed  Google Scholar 

  45. Wang F, Meng W, Wang B, Qiao L. Helicobacter pylori-induced gastric inflammation and gastric cancer. Cancer Lett. 2014;345(2):196–202.

    Article  CAS  PubMed  Google Scholar 

  46. Tsukanov VV, Butorin NN, Maady AS, Shtygasheva OV, Amelchugova OS, Tonkikh JL, et al. Helicobacter pylori infection, intestinal metaplasia, and gastric cancer risk in Eastern Siberia. Helicobacter. 2011;16(2):107–12.

    Article  PubMed  Google Scholar 

  47. Jaehn P, Holleczek B, Becher H, Winkler V. Histologic types of gastric cancer among migrants from the former Soviet Union and the general population in Germany: what kind of prevention do we need? Eur J Gastroenterol Hepatol. 2016;28(8):863–70.

    Article  PubMed  Google Scholar 

  48. Plummer M, de Martel C, Vignat J, Ferlay J, Bray F, Franceschi S. Global burden of cancers attributable to infections in 2012: a synthetic analysis. Lancet Glob Health. 2016;4(9):e609–16.

    Article  PubMed  Google Scholar 

  49. Cornberg M, Razavi HA, Alberti A, Bernasconi E, Buti M, Cooper C, et al. A systematic review of hepatitis C virus epidemiology in Europe, Canada and Israel. Liver Int. 2011;31(s2):30–60.

    Article  PubMed  Google Scholar 

  50. Wichmann H-E, Kaaks R, Hoffmann W, Jöckel K-H, Greiser K, Linseisen J. Die Nationale Kohorte. Bundesgesundheitsblatt-Gesundheitsforschung-Gesundheitsschutz. 2012;55(6–7):781–9.

    Article  PubMed  Google Scholar 

Download references

Acknowledgement

We want to thank to Dr. Amit Gulati, Institute of Medical Biometry and Epidemiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany for valuable comments which improved the paper.

Funding

Volker Winkler and Simone Kaucher were funded by the Deutsche Krebshilfe (Grant number 111232). Heiko Becher and Valentina Leier were supported by the German Federal Ministry of Education and Research (Grant Number 01ER1306 PERGOLA).

Author information

Authors and Affiliations

Authors

Corresponding authors

Correspondence to Volker Winkler or Heiko Becher.

Ethics declarations

Conflict of interest

The authors declare that they have no conflict of interest.

Additional information

Simone Kaucher and Valentina Leier are joint first authors.

Volker Winkler and Heiko Becher are joint senior authors.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Kaucher, S., Leier, V., Deckert, A. et al. Time trends of cause-specific mortality among resettlers in Germany, 1990 through 2009. Eur J Epidemiol 32, 289–298 (2017). https://doi.org/10.1007/s10654-017-0240-4

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10654-017-0240-4

Keywords

Navigation