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Geostatistical analysis of biomarkers of genotoxicity in cattle, Bos taurus and Bos taurus × Bos indicus, sentinels near industrial facilities

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Abstract

This study, performed at the behest of ranchers living and working down-prevailing wind from industrial facilities located in Calhoun County, Texas investigated locational risks to ecosystem health associated with proximity to specific industrial complexes. Concerns expressed were for potential genotoxicity in cattle resulting from the release of complex chemical mixtures. The Comet Assay and flow cytometric evaluation of variations in DNA content were utilized to evaluate DNA damage. Bayesian geo-statistical analysis revealed the presence of important spatial processes. The Comet assay’s optical density provided a strong indication of increased damage down-prevailing wind from the industrial complexes. Results indicated that proximity to and location down-prevailing winds from industrial facilities increased the locational risk of genotoxicity in this sentinel species.

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Notes

  1. ArcGIS®Version 9.1, Environmental Systems Research Institute, Redlands, Ca.

  2. ArcGIS®Version 9.1, Environmental Systems research Institute, Redlands, Ca.

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Acknowledgements

We would like to express our gratitude to the Vivian L. Smith Foundation and the Point Comfort, Texas ALCOA facility for providing the financial resources for completion of this project. Also, to our colleagues in Texas A&M University’s Food Animal Medicine and Surgery Service, your support and encouragement are greatly appreciated.

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Authors and Affiliations

  1. Department of Large Animal Clinical Sciences, Texas A&M University, 4475 TAMU, Mail Stop 4476, College Station, TX, 77843-4475, USA

    Wesley Bissett Jr., Robert Field, William Moyer & James A. Thompson

  2. Department of Veterinary Pathobiology, Texas A&M University, 4467 TAMU, College Station, TX, 77843-4467, USA

    Roger Smith & L. Garry Adams

  3. Department of Veterinary Integrative Biosciences, Texas A&M University, 4458 TAMU, College Station, TX, 77843-4458, USA

    Tim Phillips & H. Morgan Scott

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  1. Wesley Bissett Jr.
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  8. James A. Thompson
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Correspondence to Wesley Bissett Jr..

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Bissett, W., Smith, R., Adams, L.G. et al. Geostatistical analysis of biomarkers of genotoxicity in cattle, Bos taurus and Bos taurus × Bos indicus, sentinels near industrial facilities. Ecotoxicology 18, 87–93 (2009). https://doi.org/10.1007/s10646-008-0261-6

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