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Predictors of Suboptimal Bowel Preparation Using 3-l of Polyethylene Glycol for an Outpatient Colonoscopy: A Prospective Observational Study

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Abstract

Background

A 3-l polyethylene glycol (PEG) solution provided better bowel cleansing quality than a 2-l solution for outpatient colonoscopy. Predictors of suboptimal preparation using a 3-l PEG have not been previously reported.

Aims

To investigate the possible predictors of suboptimal bowel preparation using 3-l of PEG.

Methods

We analyzed a database of 1404 consecutive colonoscopies during a 27-month period at a community hospital. A split-dose PEG regimen was provided for morning colonoscopies, and a same-day PEG regimen was provided for afternoon colonoscopies. The level of bowel cleansing was prospectively scored according to the Boston Bowel Preparation Scale (BBPS). Possible predictors of suboptimal colon preparation, defined as a BBPS score <7, were analyzed using univariate statistics and multivariate logistic regression models.

Results

The mean age of the study population (46.7 % men) was 52.5 years (range 20–80 years, SD 11.1 years), and the majority of patients (77.6 %) underwent morning colonoscopies. A suboptimal bowel preparation was reported in 17.2 % of the observed colonoscopies. In the multivariate regression analysis, constipation (odds ratio [OR] 1.60, 95 % confidence interval [CI] 1.15–2.22), male gender (OR 1.68, 95 % CI 1.25–2.25), obesity (OR 1.76, 95 % CI 1.29–2.41), and inadequate (<80 %) PEG consumption (OR 5.4, 95 % CI 2.67–10.89) were independent predictors of a suboptimal colon preparation.

Conclusions

This prospective study identified that constipation, male gender, obesity, and inadequate intake of PEG were significant risk factors for suboptimal bowel preparation using a 3-l PEG solution for outpatient colonoscopy. Interventions of optimized colonoscopy preparation should be targeted at these patient populations.

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Authors and Affiliations

  1. Division of Gastroenterology, Department of Medicine, Evergreen General Hospital, 150 Huan-Zhong East Rd., Zhongli District, Taoyuan, 320, Taiwan

    Chi-Liang Cheng, Yen-Lin Kuo, Hsiang-Ling Hung, Yi-Ning Tsui & Bai-Ping Lee

  2. Department of Gastroenterology, Chang Gung Memorial Hospital and Chang Gung University, 5 Fu-Hsin St., Queishan District, Taoyuan, 333, Taiwan

    Nai-Jen Liu & Cheng-Hui Lin

  3. Division of Gastroenterology and Hepatology, Department of Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University, 252 Wuxing St., Xinyi District, Taipei, 110, Taiwan

    Jui-Hsiang Tang

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  1. Chi-Liang Cheng
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Correspondence to Chi-Liang Cheng.

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Cheng, CL., Liu, NJ., Tang, JH. et al. Predictors of Suboptimal Bowel Preparation Using 3-l of Polyethylene Glycol for an Outpatient Colonoscopy: A Prospective Observational Study. Dig Dis Sci 62, 345–351 (2017). https://doi.org/10.1007/s10620-016-4343-7

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  • DOI: https://doi.org/10.1007/s10620-016-4343-7

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