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Comparison of Narrow Band Imaging and Fujinon Intelligent Color Enhancement in Predicting Small Colorectal Polyp Histology

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Abstract

Background

There are limited data on the performance of narrow band imaging (NBI) and Fujinon intelligent color enhancement (FICE) for differentiating polyp histologies.

Aims

The aim of this study was to compare the diagnostic performances of NBI and FICE in differentiating neoplastic from non-neoplastic colorectal polyps <10 mm during screening colonoscopy.

Methods

A total of 955 average-risk adults undergoing screening colonoscopies were randomly allocated to NBI or FICE groups. Four board-certified staff endoscopists without prior experience using NBI or FICE participated. The main outcomes of this study were overall accuracy, sensitivity, and specificity of FICE and NBI in identifying neoplastic polyps.

Results

There was no significant difference in the number of subjects with adenoma between the NBI (143/475, 30.1 %) and FICE groups (139/480, 29.0 %) (after excluding adenoma ≥1 cm) (P > 0.05). The overall accuracy of NBI was 81.0 %, compared with 81.4 % for FICE (P = 0.867). The overall sensitivity and specificity of NBI and FICE were 84.6 and 78.0 % (P = 0.054); 75.1 and 86.5 % (P = 0.009), respectively. For polyps measuring ≤5 mm, the accuracy was 79.4 % for NBI and 80.1 % for FICE (P = 0.835; sensitivity 81.9 vs. 74.5 %, P = 0.064; specificity 75.7 vs. 88.4 %, P = 0.006).

Conclusions

The overall accuracy of NBI and FICE was similar for differentiating small polyp histologies during screening colonoscopy. However, better results should be achieved before using NBI or FICE as real-time optical biopsy of colorectal polyps in screening colonoscopy.

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Authors and Affiliations

  1. Department of Internal Medicine, Healthcare Research Institute, Seoul National University Hospital Healthcare System Gangnam Center, 737 Yeoksam-dong, Gangnam-gu, Seoul, 135-984, South Korea

    Hae Yeon Kang, Young Sun Kim, Seung Joo Kang, Goh Eun Chung, Ji Hyun Song, Sun Young Yang, Seon Hee Lim & Donghee Kim

  2. Department of Internal Medicine, Liver Research Institute, Seoul National University College of Medicine, Seoul, South Korea

    Joo Sung Kim

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  1. Hae Yeon Kang
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  2. Young Sun Kim
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Correspondence to Young Sun Kim.

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Kang, H.Y., Kim, Y.S., Kang, S.J. et al. Comparison of Narrow Band Imaging and Fujinon Intelligent Color Enhancement in Predicting Small Colorectal Polyp Histology. Dig Dis Sci 60, 2777–2784 (2015). https://doi.org/10.1007/s10620-015-3661-5

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  • DOI: https://doi.org/10.1007/s10620-015-3661-5

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