Skip to main content

Advertisement

SpringerLink
Log in

Tachykinin Peptide, Substance P, and Its Receptor Have a Significant Role in Tissue Reactions Induced by Cytotoxic Therapy

  • Correspondence
  • Published:
Digestive Diseases and Sciences Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. Matsumoto K, Nakajima T, Sakai H, et al. Increased expression of 5-HT3 and NK 1 receptors in 5-fluorouracil-induced mucositis in mouse jejunum. Dig Dis Sci. 2013;58:3440–3451.

    Article  PubMed  CAS  Google Scholar 

  2. Andrews PLR, Rudd JA. The role of tachykinins and the tachykinin NK1 receptor in nausea and emesis. In: Hofmann FB, ed. Handbook of Experimental Pharmacology. Berlin: Springer; 2004:359–440.

    Google Scholar 

  3. Santini D, Vincenzi B, Guida FM, et al. Aprepitant for management of severe pruritus related to biological cancer treatments: a pilot study. Lancet Oncol. 2012;13:1020–1024.

    Article  PubMed  CAS  Google Scholar 

  4. Höckerfelt U, Franzén L, Forsgren S. Substance P (NK1) receptor in relation to substance P innervation in rat duodenum after irradiation. Regul Pept. 2001;98:115–126.

    Article  PubMed  Google Scholar 

  5. Forsgren S, Höckerfelt U, Norrgård O, Henriksson R, Franzén L. Pronounced substance P innervation in irradiation-induced enteropathy—a study on human colon. Regul Pept. 2000;88:1–13.

    Article  PubMed  CAS  Google Scholar 

  6. Yamamoto K, Kureyama N, Asano K, Ikeda T, Yamatodani A. Involvement of substance P and the neurokinin-1 receptor in radiation-induced hair loss in mice. J Pharmacol Sci. 2010;112:118–120.

    Article  PubMed  CAS  Google Scholar 

  7. Aalto Y, Forsgren S, Kjörell U, Franzén L, Gustafsson H, Henriksson R. Time- and dose-related changes in the expression of substance P in salivary glands in response to fractionated irradiation. Int J Radiat Oncol Biol Phys. 1995;33:297–305.

    Article  PubMed  CAS  Google Scholar 

  8. Lidegran M, Domeij S, Dalqvist Å, et al. Irradiation influences the expression of substance P and enkephalin in the rat larynx. Cell Tissue Res. 1995;279:55–63.

    Article  PubMed  CAS  Google Scholar 

Download references

Conflict of interest

None.

Author information

Authors and Affiliations

  1. Department of Oncology and Palliative Medicine, Velindre Hospital, Cardiff University, Cardiff, CF14 2TL, Wales, UK

    P. S. Satheeshkumar

  2. Department of Oral Medicine and Radiology, Mar Baselios Dental College, Kerala University of Health Sciences, Thankalam, Kothamangalam, Ernakulam, 686691, Kerala, India

    P. S. Satheeshkumar & Minu P. Mohan

Authors
  1. P. S. Satheeshkumar
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Minu P. Mohan
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to P. S. Satheeshkumar.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Satheeshkumar, P.S., Mohan, M.P. Tachykinin Peptide, Substance P, and Its Receptor Have a Significant Role in Tissue Reactions Induced by Cytotoxic Therapy. Dig Dis Sci 59, 2600–2601 (2014). https://doi.org/10.1007/s10620-014-3286-0

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10620-014-3286-0

Keywords

Search

Navigation