Digestive Diseases and Sciences

, Volume 53, Issue 5, pp 1358–1363

Ethnicity and Nonalcoholic Fatty Liver Disease in an Obesity Clinic: The Impact of Triglycerides

Authors

    • Department of MedicineUniversity of Illinois at Chicago
    • Section of Digestive Diseases and Nutrition (MC 716)
  • Mrudula Kumar
    • Department of MedicineUniversity of Illinois at Chicago
  • Radhika Aggarwal
    • Department of MedicineUniversity of Illinois at Chicago
  • Reed Berger
    • Department of MedicineUniversity of Illinois at Chicago
  • Jennifer Layden-Almer
    • Department of MedicineUniversity of Illinois at Chicago
  • Neil Gupta
    • Department of MedicineUniversity of Illinois at Chicago
  • Scott J. Cotler
    • Department of MedicineUniversity of Illinois at Chicago
Original Paper

DOI: 10.1007/s10620-008-0234-x

Cite this article as:
Kallwitz, E.R., Kumar, M., Aggarwal, R. et al. Dig Dis Sci (2008) 53: 1358. doi:10.1007/s10620-008-0234-x

Abstract

Nonalcoholic fatty liver disease (NAFLD) is a growing problem that is associated with the metabolic syndrome. The goal of the present study was to evaluate for ethnic differences in NAFLD and clinical correlates of NAFLD. The study population consisted of 567 patients seen at an urban obesity clinic. Elevated aminotransferase levels were used as a surrogate marker for NAFLD. The prevalence of elevated aminotransferases was highest in Hispanics (39%), followed by Caucasians (28%), and African Americans (12%). In univariate analysis, elevated aminotransferase levels were associated with ethnicity (Hispanic > African American, P < 0.001, and Caucasian > African American P = 0.030), hypertriglyceridemia (P < 0.001), and male gender (P < 0.001). The pattern of results was confirmed in multivariate analysis, except that the differences between Caucasians and African Americans was no longer significant. In conclusion, in an obesity clinic population, elevated aminotransferase levels and hypertriglyceridemia were most common in Hispanics and least common in African Americans.

Keywords

Fatty liver Ethnology Triglycerides Obesity

Copyright information

© Springer Science+Business Media, LLC 2008