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A new furanocoumarin from the roots of Angelica oncosepala

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Chemistry of Natural Compounds Aims and scope

A new furanocoumarin oncosepalin A (1), together with two known compounds, ferulic acid and β-sitosterol, was isolated from the roots of Angelica oncosepala. The structure of the new compound was elucidated by spectroscopic methods, including extensive 1D and 2D NMR experiments, as well as high-resolution EI mass analysis. Compound 1 showed cytotoxic inhibition against HL-60 human tumor cell lines with an IC50 value of 2.04 μM.

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Acknowledgment

This work was financially supported by the Natural Science Foundation of Yunnan Province (No. 2008ZC110M) and the International Cooperation Foundation of Yunnan Province of China (No. 30811120009).

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Authors and Affiliations

  1. School of Pharmaceutical Science and Yunnan Key Laboratory of Pharmacology of Natural Products, Kunming Medical University, Kunming, 650500, Yunnan, P. R. China

    Bin Zheng, Chen Qing, Ji-Liang Wang, Li-Ping Tang & Xian Li

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  1. Bin Zheng
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  2. Chen Qing
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  3. Ji-Liang Wang
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  4. Li-Ping Tang
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  5. Xian Li
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Corresponding author

Correspondence to Xian Li.

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Published in Khimiya Prirodnykh Soedinenii, No. 5, September–October, 2012, pp. 672–673.

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Zheng, B., Qing, C., Wang, JL. et al. A new furanocoumarin from the roots of Angelica oncosepala . Chem Nat Compd 48, 748–750 (2012). https://doi.org/10.1007/s10600-012-0373-3

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  • DOI: https://doi.org/10.1007/s10600-012-0373-3

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