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Synthesis and properties of 2-benzylidene-8,9-dihydro-7H-furo[2,3-f][1,3]benzoxazin-3(2H)-one derivatives

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Chemistry of Heterocyclic Compounds Aims and scope

Aminomethylation of 6-hydroxyaurones with primary amines was used to synthesize 2-benzylidene-8,9-dihydro-7H-furo[2,3-f][1,3]-benzoxazin-3(2H)-one derivatives, while opening of 1,3-oxazine ring in the presence of acid gave secondary amines containing a 6-hydroxyaurone moiety. Acetylation of 2-benzylidene-8,9-dihydro-7H-furo[2,3-f][1,3]benzoxazin-3(2H)-ones was also accompanied by opening of 1,3-oxazine ring.

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Authors and Affiliations

  1. Institute of Bioorganic Chemistry and Petrochemistry, National Academy of Sciences of Ukraine, 1 Murmanska St, Kyiv, 02094, Ukraine

    Antonina V. Popova & Mykhaylo S. Frasinyuk

  2. National University of Food Technologies, 68 Volodymyrska St, Kyiv, 01601, Ukraine

    Svitlana P. Bondarenko

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  1. Antonina V. Popova
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  2. Svitlana P. Bondarenko
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  3. Mykhaylo S. Frasinyuk
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Correspondence to Mykhaylo S. Frasinyuk.

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Translated from Khimiya Geterotsiklicheskikh Soedinenii, 2016, 52(8), 592–600

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Popova, A.V., Bondarenko, S.P. & Frasinyuk, M.S. Synthesis and properties of 2-benzylidene-8,9-dihydro-7H-furo[2,3-f][1,3]benzoxazin-3(2H)-one derivatives. Chem Heterocycl Comp 52, 592–600 (2016). https://doi.org/10.1007/s10593-016-1937-0

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  • DOI: https://doi.org/10.1007/s10593-016-1937-0

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