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Reduced rates of non-union with modified periacetabular osteotomy using peracetic-acid sterilized cancellous allografts

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Abstract

The objective of the present study was to analyze the clinical and radiological results of periacetabular osteotomies (PAO) using Kirschner wire fixation and an allogeneic cancellous bone graft. This retrospective cohort study included 73 patients (85 PAOs). The allografts were processed from distal femur of cadaveric donors, defatted, sterilized with a peracetic-acid ethanol solution and freeze-dried. The clinical outcome, as measured by the Harris Hip Scores (HHS), the complication rate and the acetabular correction, as measured by radiological parameters, were compared. The postoperative femoral head coverage and HSS were significantly improved. Major complications occurred in five cases (6 %), but in no case did we observe a non-union or a graft-associated adverse effect. Fixation of the acetabular fragment with Kirschner wires in combination with an allogeneic cancellous bone graft is a safe method, with a low complication rate, no loss of correction and can prevent the occurrence of non-union with a high degree of probability.

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Authors and Affiliations

  1. Orthopedics Department, Center for Musculoskeletal Surgery, Charité - Universitätsmedizin Berlin, Rahel-Hirsch-Weg 5, 10117, Berlin, Germany

    Georgi I. Wassilew, Viktor Janz, Lisa Renner & Carsten Perka

  2. University Tissue Bank, Institute of Transfusion Medicine, Charité - Universitätsmedizin Berlin, Berlin, Germany

    Axel Pruss

Authors
  1. Georgi I. Wassilew
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  2. Viktor Janz
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  3. Lisa Renner
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  4. Carsten Perka
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  5. Axel Pruss
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Correspondence to Georgi I. Wassilew.

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Wassilew, G.I., Janz, V., Renner, L. et al. Reduced rates of non-union with modified periacetabular osteotomy using peracetic-acid sterilized cancellous allografts. Cell Tissue Bank 17, 713–720 (2016). https://doi.org/10.1007/s10561-016-9587-0

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  • DOI: https://doi.org/10.1007/s10561-016-9587-0

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