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Mouse models of breast cancer metastasis to bone

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Abstract

Breast cancer frequently metastasizes to bone, where it takes a significant toll on quality of life. Models of bone metastasis are needed in order to better understand the process of bone metastasis and to develop better treatments. Here, we discuss the available mouse models for breast cancer bone metastasis and critical techniques for imaging bone metastasis in these models.

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Authors and Affiliations

  1. Department of Oncological Sciences, Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, 84112, USA

    Kelsi L. Kretschmann & Alana L. Welm

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  1. Kelsi L. Kretschmann
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  2. Alana L. Welm
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Correspondence to Alana L. Welm.

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Kretschmann, K.L., Welm, A.L. Mouse models of breast cancer metastasis to bone. Cancer Metastasis Rev 31, 579–583 (2012). https://doi.org/10.1007/s10555-012-9378-4

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  • DOI: https://doi.org/10.1007/s10555-012-9378-4

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