Cancer Causes & Control

, Volume 21, Issue 11, pp 1895–1904

Adherence to the dietary guidelines for Americans and endometrial cancer risk

Authors

  • Urmila Chandran
    • The Cancer Institute of New JerseyRobert Wood Johnson Medical School
    • School of Public HealthUniversity of Medicine and Dentistry of New Jersey
    • The Cancer Institute of New JerseyRobert Wood Johnson Medical School
    • School of Public HealthUniversity of Medicine and Dentistry of New Jersey
  • Melony G. Williams-King
    • The Cancer Institute of New JerseyRobert Wood Johnson Medical School
    • School of Public HealthUniversity of Medicine and Dentistry of New Jersey
  • Camelia Sima
    • Department of Epidemiology and BiostatisticsMemorial Sloan-Kettering Cancer Center
  • Sharon Bayuga
    • Department of Epidemiology and BiostatisticsMemorial Sloan-Kettering Cancer Center
  • Katherine Pulick
    • Department of Epidemiology and BiostatisticsMemorial Sloan-Kettering Cancer Center
  • Homer Wilcox
    • New Jersey Department of Health and Senior Services
  • Ann G. Zauber
    • Department of Epidemiology and BiostatisticsMemorial Sloan-Kettering Cancer Center
  • Sara H. Olson
    • Department of Epidemiology and BiostatisticsMemorial Sloan-Kettering Cancer Center
Original paper

DOI: 10.1007/s10552-010-9617-3

Cite this article as:
Chandran, U., Bandera, E.V., Williams-King, M.G. et al. Cancer Causes Control (2010) 21: 1895. doi:10.1007/s10552-010-9617-3

Abstract

The Healthy Eating Index (HEI) was developed by the US Department of Agriculture with the goal of quantifying adherence to the Dietary Guidelines for Americans. The purpose of this study was to evaluate the impact of the HEI-2005 score and each of its components on endometrial cancer risk in a population-based case–control study in New Jersey. A total of 424 cases and 398 controls completed a Food Frequency Questionnaire, which was used to derive the HEI-2005 score. Odds ratios (OR) and 95% confidence intervals (CI) were calculated using unconditional logistic regression while adjusting for potential covariates, which included all major endometrial cancer risk factors. The adjusted OR for women in the highest quartile when compared to the lowest quartile was 0.83 (95% CI: 0.52–1.34). For the meat and beans component comprising meat, eggs, poultry, fish, and beans, the OR was 0.70 (95% CI: 0.45–1.11; p for trend: 0.07), with little evidence of an association with any of the individual foods. There was no indication of an association for any of the other components of the HEI or of effect modification by body mass index. This study suggested limited value for the HEI-2005 in predicting endometrial cancer risk.

Keywords

DietEndometrial cancerFoodHealthy Eating IndexFruitVegetablesGrainWhole grainDairyMeatBeansOilsSaturated fat

Copyright information

© Springer Science+Business Media B.V. 2010