Brief Communication

Breast Cancer Research and Treatment

, Volume 92, Issue 1, pp 81-84

No adverse effects of adjuvant chemotherapy on hippocampal volumein Japanese breast cancer survivors

  • Eisho YoshikawaAffiliated withPsycho-Oncology Division, National Cancer Center Research InstitutePsychiatry Division, Nippon Medical School
  • , Yutaka MatsuokaAffiliated withPsycho-Oncology Division, National Cancer Center Research InstituteAdult Mental Health Division, National Center of Neurology and Psychiatry
  • , Masatoshi InagakiAffiliated withPsycho-Oncology Division, National Cancer Center Research Institute
  • , Tomohito NakanoAffiliated withPsycho-Oncology Division, National Cancer Center Research InstituteDepartment of Psychiatry, Nagoya City University Medical School
  • , Tatsuo AkechiAffiliated withPsycho-Oncology Division, National Cancer Center Research Institute
  • , Makoto KobayakawaAffiliated withPsycho-Oncology Division, National Cancer Center Research Institute
  • , Maiko FujimoriAffiliated withPsycho-Oncology Division, National Cancer Center Research Institute
  • , Naoki NakayaAffiliated withPsycho-Oncology Division, National Cancer Center Research Institute
  • , Nobuya AkizukiAffiliated withPsycho-Oncology Division, National Cancer Center Research InstitutePsychiatry Division, National Cancer Center Hospital East
    • , Shigeru ImotoAffiliated withDivision of Breast Surgery, National Cancer Center Hospital East
    • , Koji MurakamiAffiliated withDepartment of Radiology, National Cancer Center Hospital East
    • , Yosuke UchitomiAffiliated withPsycho-Oncology Division, National Cancer Center Research Institute Email author 

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Summary

We investigated the adverse effects of adjuvant chemotherapy on the hippocampus in Japanese breast cancer survivors with (n=44) and without (n=31) adjuvant chemotherapy. There were no significant differences in hippocampal volume (magnetic resonance imaging) or additionally in memory function (Wechsler Memory Scale-Revised) between the two groups.

Keywords

adjuvant chemotherapy hippocampal volume magnetic resonance imaging memory function