Breast Cancer Research and Treatment

, Volume 92, Issue 1, pp 81–84

No adverse effects of adjuvant chemotherapy on hippocampal volumein Japanese breast cancer survivors

  • Eisho Yoshikawa
  • Yutaka Matsuoka
  • Masatoshi Inagaki
  • Tomohito Nakano
  • Tatsuo Akechi
  • Makoto Kobayakawa
  • Maiko Fujimori
  • Naoki Nakaya
  • Nobuya Akizuki
  • Shigeru Imoto
  • Koji Murakami
  • Yosuke Uchitomi
Brief Communication

DOI: 10.1007/s10549-005-1412-6

Cite this article as:
Yoshikawa, E., Matsuoka, Y., Inagaki, M. et al. Breast Cancer Res Treat (2005) 92: 81. doi:10.1007/s10549-005-1412-6

Summary

We investigated the adverse effects of adjuvant chemotherapy on the hippocampus in Japanese breast cancer survivors with (n=44) and without (n=31) adjuvant chemotherapy. There were no significant differences in hippocampal volume (magnetic resonance imaging) or additionally in memory function (Wechsler Memory Scale-Revised) between the two groups.

Keywords

adjuvant chemotherapyhippocampal volumemagnetic resonance imagingmemory function

Copyright information

© Springer 2005

Authors and Affiliations

  • Eisho Yoshikawa
    • 1
    • 2
  • Yutaka Matsuoka
    • 1
    • 3
  • Masatoshi Inagaki
    • 1
  • Tomohito Nakano
    • 1
    • 4
  • Tatsuo Akechi
    • 1
  • Makoto Kobayakawa
    • 1
  • Maiko Fujimori
    • 1
  • Naoki Nakaya
    • 1
  • Nobuya Akizuki
    • 1
    • 7
  • Shigeru Imoto
    • 5
  • Koji Murakami
    • 6
  • Yosuke Uchitomi
    • 1
  1. 1.Psycho-Oncology DivisionNational Cancer Center Research InstituteKashiwaJapan
  2. 2.Psychiatry DivisionNippon Medical SchoolTokyo
  3. 3.Adult Mental Health DivisionNational Center of Neurology and PsychiatryIchikawaTokyo
  4. 4.Department of PsychiatryNagoya City University Medical SchoolNagoyaTokyo
  5. 5.Division of Breast SurgeryNational Cancer Center Hospital EastKashiwaTokyo
  6. 6.Department of RadiologyNational Cancer Center Hospital EastKashiwaTokyo
  7. 7.Psychiatry DivisionNational Cancer Center Hospital EastKashiwaTokyo