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Pivotal roles for Streptomyces cell surface polymers in morphological differentiation, attachment and mycelial architecture

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  • Antonie van Leeuwenhoek 80th Anniversary Issue
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Abstract

Cells that are part of a multicellular structure are typically embedded in an extracellular matrix, which is produced by the community members. These matrices, the composition of which is highly diverse between different species, are typically composed of large amounts of extracellular polymeric substances, including polysaccharides, proteins, and nucleic acids. The functions of all these matrices are diverse: they provide protection, mechanical stability, mediate adhesion to surfaces, regulate motility, and form a cohesive network in which cells are transiently immobilized. In this review we discuss the role of matrix components produced by streptomycetes during growth, development and attachment. Compared to other bacteria it appears that streptomycetes can form morphologically and functionally distinct matrices using a core set of building blocks.

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Acknowledgments

The work was supported by a Vidi grant from the Dutch Applied Research Council to D.C.

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  1. Molecular Biotechnology, Institute Biology Leiden, Leiden University, Sylviusweg 72, 2300 RA, Leiden, The Netherlands

    Marloes L. C. Petrus & Dennis Claessen

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Petrus, M.L.C., Claessen, D. Pivotal roles for Streptomyces cell surface polymers in morphological differentiation, attachment and mycelial architecture. Antonie van Leeuwenhoek 106, 127–139 (2014). https://doi.org/10.1007/s10482-014-0157-9

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