Abstract
Knee frontal (adduction/abduction) and sagittal (flexion/extension) moments have been implicated in the pathomechanics of knee osteoarthritis (OA). The aim of this study was to evaluate the change in the knee sagittal moment in a cohort of patients with knee OA undergoing a biomechanical training program. Twenty-five female patients with symptomatic medial compartment knee OA were enrolled in a customized biomechanical intervention program. All patients underwent consecutive gait analyses prior to treatment initiation, and after 3 months and 9 months of therapy. Self-evaluative questionnaires, spatiotemporal gait parameters, peak knee sagittal moments, knee sagittal impulses, and duration of knee moments were compared throughout the duration of therapy. Differences between baseline and follow-up values were examined using nonparametric tests. Peak knee flexion moment (KFM) at loading response decreased significantly with therapy (p = 0.001). Duration of KFM and impulse of knee flexion also decreased significantly (p = 0.024 and p = 0.029, respectively). These changes were accompanied by increased walking velocity, significant pain reduction, and increased functional activity. Post-training kinetic evaluation demonstrated profound alterations of knee sagittal moments at the loading response KFM. We speculate that knee sagittal moments can potentially be improved in patients with knee OA over time with a biomechanical training program.
Similar content being viewed by others
References
Al-Zahrani, K. S., and A. M. Bakheit. A study of the gait characteristics of patients with chronic osteoarthritis of the knee. Disabil. Rehabil. 24:275–280, 2002.
Baliunas, A. J., D. E. Hurwitz, A. B. Ryals, et al. Increased knee joint loads during walking are present in subjects with knee osteoarthritis. Osteoarthr. Cartil. 10:573–579, 2002.
Bar-Ziv, Y., Y. Beer, Y. Ran, S. Benedict, and N. Halperin. A treatment applying a biomechanical device to the feet of patients with knee osteoarthritis results in reduced pain and improved function: a prospective controlled study. BMC Musculoskelet. Disord. 11:179, 2010.
Bejek, Z., R. Paróczai, A. Illyés, and R. M. Kiss. The influence of walking speed on gait parameters in healthy people and in patients with osteoarthritis. Knee Surg. Sports Traumatol. Arthrosc. 14:612–622, 2006.
Bejek, Z., R. Paróczai, M. Szendröi, and R. M. Kiss. Gait analysis following TKA: comparison of conventional technique, computer-assisted navigation and minimally invasive technique combined with computer-assisted navigation. Knee Surg. Sports Traumatol. Arthrosc. 19:285–291, 2011.
Childs, J. D., P. J. Sparto, G. K. Fitzgerald, M. Bizzini, and J. J. Irrgang. Alterations in lower extremity movement and muscle activation patterns in individuals with knee osteoarthritis. Clin. Biomech. (Bristol, Avon) 19:44, 2004.
Crenshaw, S. J., F. E. Pollo, and E. F. Calton. Effects of lateral-wedged insoles on kinetics at the knee. Clin. Orthop. Relat. Res. 375:185–192, 2000.
Debbi, E. M., A. Wolf, and A. Haim. Detecting and quantifying global instability during a dynamic task using kinetic and kinematic gait parameters. J. Biomech. 45:1366–1371, 2012.
Fitzgerald, G. K., S. R. Piva, and J. J. Irrgang. Reports of joint instability in knee osteoarthritis: its prevalence and relationship to physical function. Arthritis Rheum. 51:941–946, 2004.
Fregly, B. J., D. D. D’Lima, and C. W. Colwell, Jr. Effective gait patterns for offloading the medial compartment of the knee. J. Orthop. Res. 27:1016–1021, 2009.
Gok, H., S. Ergin, and G. Yavuzer. Kinetic and kinematic characteristics of gait in patients with medial knee arthrosis. Acta Orthop. Scand. 73:647–652, 2002.
Goryachev, Y., E. M. Debbi, A. Haim, and A. Wolf. The effect of manipulation of the center of pressure of the foot during gait on the activation patterns of the lower limb musculature. J. Electromyogr. Kinesiol. 21:333–339, 2011.
Haim, A., N. Rozen, S. Dekel, N. Halperin, and A. Wolf. Control of knee coronal plane moment via modulation of center of pressure: a prospective gait analysis study. J. Biomech. 41:3010–3016, 2008.
Haim, A., N. Rozen, and A. Wolf. The influence of sagittal center of pressure offset on gait kinematics and kinetics. J. Biomech. 43:969–977, 2010.
Haim, A., G. Rubin, N. Rozen, Y. Goryachev, and A. Wolf. Reduction in knee adduction moment via non-invasive biomechanical training: a longitudinal gait analysis study. J. Biomech. 45:41–45, 2012.
Hortobagyi, T., L. Westerkamp, S. Beam, et al. Altered hamstring-quadriceps muscle balance in patients with knee osteoarthritis. Clin. Biomech. (Bristol, Avon) 20:97–104, 2005.
Hurwitz, D. E., A. B. Ryals, J. P. Case, J. A. Block, and T. P. Andriacchi. The knee adduction moment during gait in subjects with knee osteoarthritis is more closely correlated with static alignment than radiographic disease severity, toe out angle and pain. J. Orthop. Res. 20:101–107, 2002.
Kadaba, M. P., H. K. Ramakrishnan, and M. E. Wootten. Measurement of lower extremity kinematics during level walking. J. Orthop. Res. 8:383–392, 1990.
Kaufman, K. R., C. Hughes, B. F. Morrey, M. Morrey, and K. N. An. Gait characteristics of patients with knee osteoarthritis. J. Biomech. 34:907–915, 2001.
Kosinski, M., S. D. Keller, J. E. Ware Jr., H. T. Hatoum, and S. X. Kong. The SF-36 Health Survey as a generic outcome measure in clinical trials of patients with osteoarthritis and rheumatoid arthritis: relative validity of scales in relation to clinical measures of arthritis severity. Med. Care 37:MS23–39, 1999.
Levinger, P., H. B. Menz, A. D. Morrow, et al. Knee biomechanics early after knee replacement surgery predict abnormal gait patterns 12 months postoperatively. J. Orthop. Res. 30:371–376, 2012.
Lewek, M. D., K. S. Rudolph, and L. Snyder-Mackler. Control of frontal plane knee laxity during gait in patients with medial compartment knee osteoarthritis. Osteoarthr. Cartil. 12:745–751, 2004.
Miyazaki, T., M. Wada, H. Kawahara, et al. Dynamic load at baseline can predict radiographic disease progression in medial compartment knee osteoarthritis. Ann. Rheum. Dis. 61:617–622, 2002.
Pham, T., D. van der Heijde, R. D. Altman, J. J. Anderson, N. Bellamy, M. Hochberg, L. Simon, V. Strand, T. Woodworth, and M. Dougados. OMERACT-OARSI initiative: Osteoarthritis Research Society International set of responder criteria for osteoarthritis clinical trials revisited. Osteoarthr. Cartil. 12:389–399, 2004.
Roos, E. M., M. Klassbo, and L. S. Lohmander. WOMAC osteoarthritis index. Reliability, validity, and responsiveness in patients with arthroscopically assessed osteoarthritis. Western Ontario and MacMaster Universities. Scand. J. Rheumatol. 28:210–215, 1999.
Rose, J., and J. G. Gamble. Human Walking, Vol. 3. Philadelphia: Lippincott Williams & Wilkins, 2006.
Schipplein, O. D., and T. P. Andriacchi. Interaction between active and passive knee stabilizers during level walking. J. Orthop. Res. 9:113–119, 1991.
Sharma, L., D. E. Hurwitz, E. J. Thonar, et al. Knee adduction moment, serum hyaluronan level, and disease severity in medial tibiofemoral osteoarthritis. Arthritis Rheum. 41:1233–1240, 1998.
Sharma, L., C. Lou, D. T. Felson, et al. Laxity in healthy and osteoarthritic knees. Arthritis Rheum. 42:861–870, 1999.
Shimada, S., S. Kobayashi, M. Wada, et al. Effects of disease severity on response to lateral wedged shoe insole for medial compartment knee osteoarthritis. Arch. Phys. Med. Rehabil. 87:1436–1441, 2006.
Winter, D. A. The Biomechanics and Motor Control of Human Gait, Vol. 2. Waterloo, ON: University of Waterloo Press, 1991.
Yasuda, K., and T. Sasaki. The mechanics of treatment of the osteoarthritic knee with a wedged insole. Clin. Orthop. Relat. Res. 215:162–172, 1987.
Zajac, F. E., R. R. Neptune, and S. A. Kautz. Biomechanics and muscle coordination of human walking. Part I: introduction to concepts, power transfer, dynamics and simulations. Gait Posture 16:215–232, 2002.
Acknowledgments
The authors thank APOS-Medical and Sports Technologies Ltd. for their generosity in contributing the devices used in the study.
Funding statement
This research received no specific grant from any funding agency in the public, commercial or not-for-profit sectors.
Conflict of interest
No author has any conflict of interest to declare.
Author information
Authors and Affiliations
Corresponding author
Additional information
Associate Editor Amit Gefen oversaw the review of this article.
Rights and permissions
About this article
Cite this article
Debbi, E.M., Wolf, A., Goryachev, Y. et al. Alterations in Sagittal Plane Knee Kinetics in Knee Osteoarthritis Using a Biomechanical Therapy Device. Ann Biomed Eng 43, 1089–1097 (2015). https://doi.org/10.1007/s10439-014-1177-3
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s10439-014-1177-3