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Numerical analysis for the efficacy of nasal surgery in obstructive sleep apnea hypopnea syndrome

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  • Bio-mechanics
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Abstract

In the present study, we reconstructed upper airway and soft palate models of 3 obstructive sleep apnea—hypopnea syndrome (OSAHS) patients with nasal obstruction. The airflow distribution and movement of the soft palate before and after surgery were described by a numerical simulation method. The curative effect of nasal surgery was evaluated for the three patients with OSAHS. The degree of nasal obstruction in the 3 patients was improved after surgery. For 2 patients with mild OSAHS, the upper airway resistance and soft palate displacement were reduced after surgery. These changes contributed to the mitigation of respiratory airflow limitation. For the patient with severe OSAHS, the upper airway resistance and soft palate displacement increased after surgery, which aggravated the airway obstruction. The efficacy of nasal surgery for patients with OSAHS is determined by the degree of improvement in nasal obstruction and whether the effects on the pharynx are beneficial. Numerical simulation results are consistent with the polysomnogram (PSG) test results, chief complaints, and clinical findings, and can indirectly reflect the degree of nasal patency and improvement of snoring symptoms, and further, provide a theoretical basis to solve relevant clinical problems.

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References

  1. Pevernagic, D.A., De Meyer, M.M., Claevs, S.: Sleep, breathing and the nose. Sleep Medicine Reviews 9, 437–451 (2005)

    Article  Google Scholar 

  2. Kohler, M., Bloch, K.E., Stradling, J.R.: The role of the nose in the pathogenesis of obstructive sleep apnea. Current Opinion in Otolaryngology & Head and Neck Surgery 17, 33–37 (2009)

    Article  Google Scholar 

  3. Georgalas, C.: The role of the nose in snoring and obstructive sleep apnoea: An update. European Archives of Oto-Rhino-Laryngology 268, 1365–1373 (2011).

    Article  Google Scholar 

  4. Verse, T., Maurer, J.T., Pirsig, W.: Effect of nasal surgery on Sleep-related breathing disorders. Laryngoscope 112, 64–68 (2002)

    Article  Google Scholar 

  5. Li, H.Y., Lin, Y., Chen, N.H., et al.: Improvement in quality of life after nasal surgery alone for patients with obstructive sleep apnea and nasal obstruction. Archives of Otolaryngology-Head & Neck Surgery 134, 429–433 (2008)

    Article  Google Scholar 

  6. Kim, S.T., Choi, J.H., Jeon, H.J., et al.: Polysomnographic effects of nasal surgery for snoring and obstructive sleep apnea. Acta Oto-laryngologica 124, 297–300 (2004)

    Article  Google Scholar 

  7. Tosun, F., Kemikli, K., Yetkin, S., et al.: Impact of endoscopic sinus surgery on sleep quality in patients with chronic nasal obstruction due to nasal polyposis. Journal of Craniofacial Surgery 20, 446–449 (2004)

    Article  Google Scholar 

  8. Verse, T., Pirsig, W.: Impact of impaired nasal breathing on sleep-disordered breathing. Sleep and Breathing 7, 63–76 (2003)

    Article  Google Scholar 

  9. Mihaescu, M., Murugappan, S., Gutmark, E., et al.: Computational modeling of upper airway before and after adenotonsillectomy for obstructive sleep apnea. The Laryngoscope 118, 360–362 (2008)

    Article  Google Scholar 

  10. Huynh, J., Kim, K.B., McQuiling, M., et al.: Pharyngeal airflow analysis in obstructive sleep apnea patients pre- and post-maxillomandibular advancement surgery. Journal of Fluids Engineering 131, 091101.1–091101.10 (2009)

    Article  Google Scholar 

  11. Powell, N.B., Mihaescu, M., Mylavarapu, G., et al.: Patterns in pharyngeal airflow associated with sleep-disordered breathing. Sleep Medicine 12, 966–974 (2011)

    Article  Google Scholar 

  12. Huang, Y., White, D. P., Malhotra, A.: Use of computational modeling to predict responses to upper airway surgery in obstructive sleep apnea. The Laryngoscope 117, 648–653 (2007)

    Article  Google Scholar 

  13. Payan, Y., Pelorson, X., Perrier, P.: Physical modelling of the airflow-walls interactions to understand the sleep apnea syndrome. Lecture Notes in Computer Science 2673, 261–269 (2003)

    Article  Google Scholar 

  14. Malhotra, A., Huang, Y., Fogel, R.B., et al.: The male predisposition to pharyngeal collapse: Importance of airway length. American Journal of Respiratory and Critical Care Medicine 116, 1388–1395 (2002)

    Article  Google Scholar 

  15. Huang, Y., White, D.P., Malhotra, A.: The impact of anatomic manipulations on pharyngeal collapse: Results from a computational model of the normal human upper airway. Chest 128, 1324–1330 (2005)

    Article  Google Scholar 

  16. Xu, C.: Computational mechanics models for studying the pathogenesis of obstructive sleep apnea (OSA), [PhD Thesis]. Drexel University, Philadelphia (2005)

    Google Scholar 

  17. Chouly, F., van Hirtum, A., Lagree, P.Y., et al.: Numerical and experimental study of expiratory flow in the case of major upper airway obstructions with fluid-structure interaction. Journal of Fluids and Structures 24, 250–269 (2008)

    Article  Google Scholar 

  18. Xu, C., Brennick, M.J., Dougherty, L., et al.: Modeling upper airway collapse by a finite element model with regional tissue properties. Medical Engineering & Physics 31, 1343–1348 (2009)

    Article  Google Scholar 

  19. Xia, G., Tawhai, M.H., Hoffman, E.A., et al.: Airway wall stiffening increases peak wall shear stress: A fluid-structure interaction study in rigid and compliant airways. Annals of Biomedical Engineering 38, 1836–1853 (2010)

    Article  Google Scholar 

  20. Pan, X., Qian, Y., Yu, J., et al.: Biomechanical effects of rapid palatal expansion on the craniofacial skeleton with cleft palate: a three-dimensional finite element analysis. The Cleft Palate-Craniofacial Journal 44, 149–154 (2007)

    Article  Google Scholar 

  21. Qureshi, A., Ballard, R.D.: Obstructive sleep apnea. Journal of Allergy and Clinical Immunology 112, 643–652 (2003)

    Article  Google Scholar 

  22. Rama, A.N., Tekwani, S.H., Kushida, C.A.: Sites of obstruction in obstructive sleep apnea. Chest 122, 1139–1147 (2002)

    Article  Google Scholar 

  23. Sher, A. E.: Upper airway surgery for obstructive sleep apnea. Sleep Medicine Reviews 6, 195–212 (2002)

    Article  Google Scholar 

  24. Powell, N.B., Mihaescu, M., Mylavarapu, G., et al.: Patterns in pharyngeal airflow associated with sleep-disordered breathing. Sleep Med 12, 966–974 (2011)

    Article  Google Scholar 

  25. Brugel, R.L., Fodil, R., Coste, A., et al.: Segmental analysis of nasal cavity compliance by acoustic rhinometry. Journal of Applied Physics 93, 304–310 (2002)

    Google Scholar 

  26. Haight, J.S., Cole, P.: The site and function of the nasal valve. The Laryngoscope 93, 49–55 (1983)

    Article  Google Scholar 

  27. Mylavarapu, G., Mihaescu, M., Gutmark, E.J., et al.: Fluidstructure interaction analysis in human upper airways to understand sleep apnea. In: Proc. of 48th AIAA Aerospace Science Meeting, January 2010, Orlando, Florida (2010)

    Google Scholar 

  28. Wen, W.S., Hu, M., Liu, C.M., et al.: Relationship between soft palate and retropatal airway in different posture. Academic Journal of Pla Postgraduate Medical School 22, 57–59 (2001)

    Google Scholar 

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Correspondence to Ying-Xi Liu or Xiu-Zhen Sun.

Additional information

The project was supported by the National Natural Science Foundation of China (10902022, 11072055, and 11032008) and the Fundamental Research Funds for the Central Universities (DUT13LK49).

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Yu, S., Liu, YX., Sun, XZ. et al. Numerical analysis for the efficacy of nasal surgery in obstructive sleep apnea hypopnea syndrome. Acta Mech Sin 30, 250–258 (2014). https://doi.org/10.1007/s10409-014-0037-6

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  • DOI: https://doi.org/10.1007/s10409-014-0037-6

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