Skip to main content
SpringerLink
Log in

Laparoscopic ultrasound procedure can reduce residual myomas in laparoscopic myomectomy for multiple myomas

  • Original Article
  • Published:
Journal of Medical Ultrasonics Aims and scope Submit manuscript

Abstract

Purpose

To clarify whether the use of laparoscopic ultrasound (LUS) during laparoscopic myomectomy could reduce the number of residual myomas after surgery.

Methods

A cohort study was conducted. Subjects were women who underwent laparoscopic myomectomy for multiple uterine myomas for the first time. The subjects were assigned to one of two groups: LUS group or non-LUS group. All subjects underwent pelvic MRI 3 months before and 6 months after surgery, and the number of myomas on MRI was counted by radiodiagnosticians. The extraction rate and residual rate of uterine myomas were compared between the two groups.

Results

Fourteen cases with and 30 cases without LUS were analyzed. Median operation times were 171 min (range 75–295) and 141 min (range 50–260) in cases with and without LUS, respectively (p = 0.077). Median extraction rates relative to the total number of myomas were 106 % (range 75–147 %) in subjects with LUS and 100 % (range 71–233 %) in subjects without LUS (p = 0.480). Numbers of residual myomas were 1 (range 0–3) in subjects with LUS and 2 (range 0–9) in subjects without LUS (p = 0.028). Median residual rates of myomas were 6.1 % (range 0–20 %) in subjects with LUS and 20.0 % (range 0–69 %) in subjects without LUS (p = 0.048). Myomas greater than 3 cm in diameter were not observed in either group.

Conclusions

The number and residual rate of myomas were significantly less in subjects with LUS as compared with those without LUS.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5

Similar content being viewed by others

References

  1. Bettocchi S, Siristatidis C, Pontrelli G, et al. The destiny of myomas: should we treat small submucous myomas in women of reproductive age? Fertil Steril. 2008;90:905–10.

    Article  PubMed  Google Scholar 

  2. Andersen J. Growth factors and cytokines in uterine leiomyomas. Semin Reprod Endocrinol. 1996;14:269–82.

    Article  CAS  PubMed  Google Scholar 

  3. Peddada SD, Laughlin SK, Miner K, et al. Growth of uterine leiomyomata among premenopausal black and white women. Proc Natl Acad Sci USA. 2008;105:19887–92.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  4. Nishiyama S, Saito M, Sato K, et al. High recurrence rate of uterine fibroids on transvaginal ultrasound after abdominal myomectomy in Japanese women. Gynecol Obstet Investig. 2006;61:155–9.

    Article  Google Scholar 

  5. Malone LJ. Myomectomy: recurrence after removal of solitary and multiple myomas. Obstet Gynecol. 1969;34:200–3.

    CAS  PubMed  Google Scholar 

  6. Lin PC, Thyer A, Soules MR. Intraoperative ultrasound during a laparoscopic myomectomy. Fertil Steril. 2004;81:1671–4.

    Article  PubMed  Google Scholar 

  7. Seracchioli R, Rossi S, Govoni F, et al. Fertility and obstetric outcome after laparoscopic myomectomy of large myomata: a randomized comparison with abdominal myomectomy. Hum Reprod. 2000;15:2663–8.

    Article  CAS  PubMed  Google Scholar 

  8. Rossetti A, Sizzi O, Soranna L, et al. Long-term results of laparoscopic myomectomy: recurrence rate in comparison with abdominal myomectomy. Hum Reprod. 2001;16:770–4.

    Article  CAS  PubMed  Google Scholar 

  9. Marret H, Chevillot M, Giraudeau B, et al. A retrospective multicentre study comparing myomectomy by laparoscopy and laparotomy in current surgical practice. What are the best patient selection criteria? Eur J Obstet Gynecol Reprod Biol. 2004;117:82–6.

    Article  PubMed  Google Scholar 

  10. Fedele L, Vercellini P, Bianchi S, et al. Treatment with GnRH agonists before myomectomy and the risk of short-term myoma recurrence. Br J Obstet Gynaecol. 1990;97:393–6.

    Article  CAS  PubMed  Google Scholar 

  11. Gigot JF, Glineur D, Santiago, et al. Laparoscopic liver resection for malignant liver tumors: preliminary results of a multicenter European study. Ann Surg. 2002;236:90–7.

    Article  PubMed  PubMed Central  Google Scholar 

  12. Belli G, Fantini C, D’Agostino, et al. Laparoscopic liver resections for hepatocellular carcinoma (HCC) in cirrhotic patients. HPB Oxf. 2004;6:236–46.

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Obstetrics and Gynecology, Showa University School of Medicine, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo, 142-8666, Japan

    Takashi Mimura, Junichi Hasegawa, Tetsuya Ishikawa & Akihiko Sekizawa

Authors
  1. Takashi Mimura
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Junichi Hasegawa
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Tetsuya Ishikawa
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Akihiko Sekizawa
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Takashi Mimura.

Ethics declarations

Conflict of interest

The authors have no conflict of interest or financial ties to disclose.

Ethical approval

All procedures followed were in accordance with the ethical standards of the responsible committee on human experimentation (institutional and national) and with the Helsinki Declaration of 1975, as revised in 2008.

Informed consent

Informed consent was obtained from all patients for being included in the study.

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Mimura, T., Hasegawa, J., Ishikawa, T. et al. Laparoscopic ultrasound procedure can reduce residual myomas in laparoscopic myomectomy for multiple myomas. J Med Ultrasonics 43, 407–412 (2016). https://doi.org/10.1007/s10396-016-0714-0

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10396-016-0714-0

Keywords

Search

Navigation