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Utilization of partition analysis to evaluate the incidence on deep vein thrombosis following esophagectomy

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Abstract

Background

We performed a retrospective observational study to examine the involvement of suspicious factors and causes of deep vein thrombosis using cases of esophagectomy that were done to treat esophageal carcinoma.

Methods

The 144 patients received esophagectomy in Okayama University Hospital from January 2005 to June 2007. All patients had an enhanced CT or an ultrasound examination after their operations. The incidence of deep vein thrombosis was then determined. For cases that found deep vein thrombosis, the anticoagulant treatment was strengthened. When the thrombosis was already so large to be seen in the inferior vena cava, the IVC filter was left to prevent a pulmonary embolism. Using JMP5.0.1 statistical analysis software, we analyzed the relationship between various clinical factors and the incidence of deep vein thrombosis.

Results

Using JMP5.0.1, factors causing deep vein thrombosis were analyzed and partitioning was done. The most significant risk factor causing deep vein thrombosis is leaving the central venous catheter inserted into the inguinal femoral area. Logistic analysis also showed that only the catheter if inserted from the inguinal femoral area, was significantly related to cause deep vein thrombosis (p < 0.0055). No other factor was a significant risk to cause deep vein thrombosis.

Conclusions

We analyzed the relationship between suspicious factors and the causes of deep vein thrombosis in cases of esophagectomy. The most relevant factors were inserting the central venous catheter from the inguinal femoral route. This evidence can be applied to both pre-operative and postoperative management to prevent deep vein thrombosis.

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Conflict of interest

None declared.

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Authors and Affiliations

  1. Department of Surgery, Hiroshima City Hospital, Hiroshima, 701-0202, Japan

    Yasuhiro Fujiwara

  2. Department of Gastroenterological Surgery, Okayama University, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, 700-8558, Japan

    Yasuhiro Fujiwara, Shunsuke Tanabe, Kazufumi Sakurama, Takayuki Motoki, Yasuhiro Shirakawa & Junji Matsuoka

  3. Department of General Surgery, Kawasaki Medical School, 2-1-80 Nakasange, Kita-ku, Okayama, 700-8505, Japan

    Tomoki Yamatsuji, Munenori Takaoka, Takuya Fukazawa & Yoshio Naomoto

  4. Shigei Medical Research Institute and Hospital, Okayama, 730-0011, Japan

    Kazufumi Sakurama

  5. Okayama Citizens’ Hospital, Okayama, 700-8557, Japan

    Minoru Haisa

Authors
  1. Yasuhiro Fujiwara
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  2. Tomoki Yamatsuji
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  3. Shunsuke Tanabe
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  4. Kazufumi Sakurama
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  5. Takayuki Motoki
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  6. Munenori Takaoka
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  7. Takuya Fukazawa
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  8. Yasuhiro Shirakawa
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  9. Minoru Haisa
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  10. Junji Matsuoka
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  11. Yoshio Naomoto
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Corresponding author

Correspondence to Yoshio Naomoto.

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Fujiwara, Y., Yamatsuji, T., Tanabe, S. et al. Utilization of partition analysis to evaluate the incidence on deep vein thrombosis following esophagectomy. Esophagus 10, 1–5 (2013). https://doi.org/10.1007/s10388-012-0350-8

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  • DOI: https://doi.org/10.1007/s10388-012-0350-8

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