Skip to main content
SpringerLink
Log in

Episodes of hypo- and hypercapnia in a cohort of mechanically ventilated VLBW infants: the role of adequate staffing

  • short communication
  • Published:
Wiener Medizinische Wochenschrift Aims and scope Submit manuscript

Summary

In preterm neonates, the use of invasive ventilation may be mandatory because of respiratory distress syndrome (RDS). In this short communication, we demonstrate that invasive ventilation in this susceptible cohort may be associated with episodes of both hypo- and hypercapnia, and that inadequate ventilatory support is associated with the occurrence rate of bronchopulmonary dysplasia (BPD; p < 0.05). Also, inadequate mechanical ventilation is aggravated by a shortage of medical staff.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Abbreviations

BPD:

Bronchopulmonary dysplasia

CPAP:

Continuous positive airway pressure

LISA:

Less invasive surfactant application

NICU:

Neonatal intensive care unit

PICU:

Pediatric intensive care unit

PVL:

Periventricular leukomalacia

RDS:

Respiratory distress syndrome

ROP:

Retinopathy of prematurity

VLBW:

Very low birth weight

References

  1. Thome UH, Genzel-Boroviczeny O, Bohnhorst B, Schmid M, Fuchs H, Rohde O, Avenarius S, Topf HG, Zimmermann A, Faas D, Timme K, Kleinlein B, Buxmann H, Schenk W, Segerer H, Teig N, Gebauer C, Hentschel R, Heckmann M, Schlösser R, Peters J, Rossi R, Rascher W, Böttger R, Seidenberg J, Hansen G, Zernickel M, Alzen G, Dreyhaupt J, Muche R, Hummler HD, PHELBI Study Group. Permissive hypercapnia in extremely low birthweight infants (PHELBI): a randomised controlled multicentre trial. Lancet Respir Med. 2015;3:534–43.

    Article  PubMed  Google Scholar 

  2. Göpel W, Kribs A, Ziegler A, Laux R, Hoehn T, Wieg C, Siegel J, Avenarius S, von der Wense A, Vochem M, Groneck P, Weller U, Möller J, Härtel C, Haller S, Roth B, Herting E, German Neonatal Network. Avoidance of mechanical ventilation by surfactant treatment of spontaneously breathing preterm infants (AMV): an open-label, randomised, controlled trial. Lancet. 2011;378(9803):1627–34.

    Article  PubMed  Google Scholar 

  3. Qualitätssicherungs-Richtlinie Früh- und Reifgeborene – QFR-RL. https://www.g-ba.de/informationen/richtlinien/41/ (Latest update: 27 Nov 2015). Accessed 9 May 2016.

  4. van Kaam AH, De Jaegere AP, Rimensberger PC. Neovent Study Group Incidence of hypo- and hyper-capnia in a cross-sectional European cohort of ventilated newborn infants. Arch Dis Child Fetal Neonatal Ed. 2013;98(4):F323–6.

    Article  PubMed  Google Scholar 

  5. Rogowski JA, Staiger D, Patrick T, Horbar J, Kenny M, Lake ET. Nurse staffing and NICU infection rates. JAMA Pediatr. 2013;167:444–50.

    Article  PubMed  PubMed Central  Google Scholar 

  6. Bruschettini M, Romantsik O, Zappettini S, Ramenghi LA, Calevo MG. Transcutaneous carbon dioxide monitoring for the prevention of neonatal morbidity and mortality. Cochrane Database Syst Rev. 2016;2:CD011494. doi:10.1002/14651858.CD011494.pub2.

    PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Medical School, University Hospital of Saarland, Homburg, Germany

    Maike Röhr MS

  2. Department of Pediatric Cardiology, University Hospital of Saarland, Homburg, Germany

    Martin Poryo MD

  3. Department of Pediatrics and Neonatology, University Hospital of Saarland, Building 9, 66421, Homburg, Germany

    Johannes Bay MD,  Ludwig Gortner MD &  Sascha Meyer

Authors
  1. Maike Röhr MS
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Martin Poryo MD
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Johannes Bay MD
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Ludwig Gortner MD
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Sascha Meyer
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Sascha Meyer.

Ethics declarations

Conflict of interest

M. Röhr, M. Poryo, J. Bay, L. Gortner and S. Meyer declare that they have no competing interests.

Additional information

Maike Röhr und Sascha Meyer contributed equally to this work.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Röhr, M., Poryo, M., Bay, J. et al. Episodes of hypo- and hypercapnia in a cohort of mechanically ventilated VLBW infants: the role of adequate staffing. Wien Med Wochenschr 167, 256–258 (2017). https://doi.org/10.1007/s10354-016-0506-6

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10354-016-0506-6

Keywords

Search

Navigation