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Characterization of Titanium Tiles as Novel Platforms for Micro-Flame Ionization Detection in Miniature Gas Chromatography

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Abstract

A titanium miniature gas chromatography device with an on-board micro-flame ionization detector (Ti µGC-FID) is presented. The design is based on a counter-current method that establishes a stable flame (~240 µm diameter) inside a 1.44 mm circular cavity within the Ti tile. The width of this cavity is found to have a significant impact on flame stability and detector performance. Through polarizing the conductive Ti tile body and situating a collector adjacent to the cavity, useful µFID response is obtained from the flame. The 7.5 cm × 15 cm rectangular monolithic Ti device contains a serpentine column layout (5 m long × 100 μm wide) coated with OV-101 stationary phase that is directly integrated with the on-board μFID. The column produces reasonable analyte peak symmetry and separation performance with a plate height of 1.5 mm for dodecane. Under optimized conditions, the Ti μGC-FID device yields a detection limit of 9 × 10−12 gC s−1, a linear response over 3 orders of magnitude, a sensitivity of 60 mC gC−1, and a signal reproducibility within 5% RSD (n = 10). Some samples are analyzed using the Ti µGC-FID device and results indicate that this approach can potentially provide a useful alternative means of achieving sensitive and stable μFID performance within a robust, integrated miniaturized GC platform.

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Acknowledgements

The authors gratefully acknowledge Waters Corporation for their support of this work.

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Authors and Affiliations

  1. Department of Chemistry, University of Calgary, 2500 University Drive, NW, Calgary, AB, T2N 1N4, Canada

    Rahul P. Raut & Kevin B. Thurbide

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  1. Rahul P. Raut
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  2. Kevin B. Thurbide
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Correspondence to Kevin B. Thurbide.

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This study was funded by Waters Corporation.

Conflict of interest

The authors, K. Thurbide and R. Raut, received research funding from Waters Corporation for the purpose of carrying out this research work.

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This article does not contain any studies with human participants or animals performed by any of the authors.

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Raut, R.P., Thurbide, K.B. Characterization of Titanium Tiles as Novel Platforms for Micro-Flame Ionization Detection in Miniature Gas Chromatography. Chromatographia 80, 805–812 (2017). https://doi.org/10.1007/s10337-017-3281-7

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  • DOI: https://doi.org/10.1007/s10337-017-3281-7

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