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Proton CSI without solvent suppression with strongly reduced field gradient related sideband artifacts

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Abstract

Object

Non-water-suppressed MRSI (magnetic resonance spectroscopy imaging) offers a number of advantages; however, spectra are hampered by the sideband artifacts. The origin of those is associated with the vibration of the gradient coils, and most of the sidebands are assumed to be related to the crusher gradients. The aim was to examine the dependency between the physical direction of the crushers and the sidebands. Additionally, the possibilities of optimization of the point resolved spectroscopy sequence (PRESS) were investigated.

Materials and methods

For the assessment of the sidebands, spectra at short echo time (TE) were collected at 3 T from standard water phantom. A homemade agar phantom was used to test the optimal strength of the crusher gradients. Optimized PRESS sequence was tested in vivo.

Results

The greatest sidebands were found to be associated with the crusher gradient in x-direction. Agar phantom and in vivo measurements revealed that reduction of the crusher’s strength to 5 mT/m could provide a significant minimization of the sidebands without raising the unwanted signals produced by volume selection.

Conclusion

This study demonstrates that crusher gradients in different directions produce a unique pattern of the sidebands. Moreover, optimization of the strength of crushers has been found to decrease sidebands so, the remaining part could be reduced in postprocessing.

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Acknowledgments

The authors would like to acknowledge Alessandro Greco, Dominik Zietlow, Clemens Beeken and Mario Jendrossek from the Kepler-Gymnasium in Tuebingen for their help during the measurements. Their work was done as a part of a scientific project founded by the German Research Foundation (DFG KL 1073/7-1). This study was supported by the German Research Foundation (DFG KL 1073/7-1).

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Correspondence to Grzegorz L. Chadzynski.

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Chadzynski, G.L., Klose, U. Proton CSI without solvent suppression with strongly reduced field gradient related sideband artifacts. Magn Reson Mater Phy 26, 183–192 (2013). https://doi.org/10.1007/s10334-012-0338-3

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  • DOI: https://doi.org/10.1007/s10334-012-0338-3

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