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Phenolic content and antioxidant activity of Artemisa herba-alba, a medicinal plant from Algerian arid zone

Teneur en composés phénoliques et activité antioxydante d’Artemisa herba-alba d’une région aride algérienne

  • Pharmacognosie
  • Published:
Phytothérapie

Abstract

Several researches have confirmed the pharmacological efficiency of medicinal plants that grow in arid zone. Artemisia herba-alba is a plant that grows in El bayadh region (Western Algeria) and used in traditional therapy. The present work is about phytochemical screening with quantification of phenolic compounds and determination of its antioxidant activity using different solvent maceration extract of aerial parts. Results highlighted the richness in phenolic compounds and antioxidants of this plant.

Résumé

Plusieurs recherches ont approuvé l’efficacité pharmacologique des plantes médicinales des zones arides. Artemisia herba-alba pousse dans la région d’El-Bayadh (Algérie occidentale). Elle est utilisée en médecine traditionnelle par la population locale. Le présent travail est une étude phytochimique pour la quantification de ses constituants phénoliques et une détermination de l’activité antioxydante de trois extraits de sa partie aérienne. Les résultats ont montré que la plante est riche en polyphénols (phénols totaux, flavonoïdes totaux et tanins condensés) et qu’elle possède un pouvoir antioxydant important.

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References

  1. Hung TM, Na M, Thuong PT, et al (2006) Antioxidant activity of caffeoyl quinic acid derivatives from the roots of Dipsacus asper Wall. J Ethnopharmacol 108:188–92

    Article  CAS  PubMed  Google Scholar 

  2. Lee S, Son K, Chang H, et al (1993) Anti-inflammatory activity of naturally occurring flavone and flavonol glycosides. Arch Pharm Res 16:25–8

    Article  CAS  Google Scholar 

  3. Vessal M, Hemmati M, Vasei M (2003) Antidiabetic effects of quercetin in streptozocin-induced diabetic rats. Comp Biochem Physiol C Toxicol Pharmacol 135:357–64

    Article  Google Scholar 

  4. Vivian C, Elliott M, Jeffrey B (1985) Plant flavonoids in biology and medicine. Biochemical, pharmacological, and structure-activity relationships. (New York) Proceedings of a symposium 1:22–6

    Google Scholar 

  5. Shaikh R, Pund M, Dawane A, Iliyas S (2014) Evaluation of anticancer, antioxidant, and possible anti-inflammatory properties of selected medicinal plants used in Indian traditional medication. J Tradit Complement Med 4:253–57

    Article  PubMed  PubMed Central  Google Scholar 

  6. Aruoma OI (1998) Free radicals, oxidative stress, and antioxidants in human health and disease. J Am Oil Chem Soc 75:199–212

    Article  CAS  Google Scholar 

  7. Gosslau A, Chen KY (2004) Nutraceuticals, apoptosis, and disease prevention. Nutrition 20:95–102

    Article  CAS  PubMed  Google Scholar 

  8. Podsedek A (2007) Natural antioxidants and antioxidant capacity of brassica vegetables: a review. LWT 40:1–11

    Article  CAS  Google Scholar 

  9. Korekar G, Stobdan T, Singh H, et al (2011) Phenolic content and antioxidant capacity of various solvent extracts from seabuckthorn (Hippophae rhamnoides L.) fruit pulp, seeds, leaves and stem bark. Acta Aliment Hung 40:449–58

    Article  CAS  Google Scholar 

  10. Korekar G, Stobdan T, Arora R, et al (2012) Antioxidant capacity and phenolics content of apricot (Prunus armeniaca L.) kernel as a function of genotype. Plant Foods Hum Nutr 66:376–83

    Article  Google Scholar 

  11. McArthur ED (1979) Sagebrush systematics and evolution. In: Sagebrush ecosystem symposium. Utah State University, Logan, pp. 14–22

    Google Scholar 

  12. Mabberley DJ (1990) The plant-book. Cambridge University Press, Cambridge, 245 p

    Google Scholar 

  13. Ling YR (1991) The old world Seriphidium (Compositae). Bull Bot Res (Harbin) 11:1–40

    Google Scholar 

  14. Ling YR (1991) The old world Artemisia (Compositae). Bull Bot Res (Harbin) 12:1–108

    Google Scholar 

  15. Ling YR (1995) The new world Artemisia L. In: Hind DNJ, Jeffrey C, Pope GV (eds) Advances in Compositae systematics. Royal Botanic Gardens, Kew, 281 p

    Google Scholar 

  16. Ling YR (1995) The new world Seriphidium (Besser) Fourr. In: Hind DNJ, Jeffrey C, Pope GV (eds) Advances in Compositae systematics. Royal Botanic Gardens, Kew, 291 p

    Google Scholar 

  17. Bremer K, Humphries CJ (1993) Generic monograph of the Asteraceae–Anthemideae. Bull Nat Hist Mus Lond (Bot) 23:71–177

    Google Scholar 

  18. Torrell M, Bosch M, et al (1999) Cytogenetic and isozymic characterization of the narrow endemic species Artemisia molinieri (Asteraceae, Anthemideae): Implications for its systematics and conservation. Can J Bot 77:51–60

    CAS  Google Scholar 

  19. Malagon F, Vazquez J, Delgado G, et al (1997) Antimalaric effect of an alcoholic extract of Artemisia ludoviciana mexicana in a rodent malaria model. Parasitologia 39:3–7

    CAS  Google Scholar 

  20. Newton P, White N (1999) Malaria: new developments in treatment and prevention. Annu Rev Med 50:179–92

    Article  CAS  PubMed  Google Scholar 

  21. Singh NP, Lai H (2001) Selective toxicity of dihydroartemisinin and holotransferrin toward human breast cancer cells. Life Sci 70:49–56

    Article  CAS  PubMed  Google Scholar 

  22. Jung UJ, Baek HG, Chung MH, et al (2007) The anti-diabetic effects of ethanol extract from two variants of Artemisia princeps Pampanini in C57BL/KsJ-db/db mice. Food Chem Toxicol 45:2022–9

    Article  CAS  PubMed  Google Scholar 

  23. Naili MB, Alghazeer NA, Saleh AY, et al (2010) Evaluation of antibacterial and antioxidant activities of Artemisia campestris (Astraceae) and Ziziphus lotus (Rhamnacea). Arab J Chem 3:79–84

    Article  CAS  Google Scholar 

  24. Rustaiyan A, Masoudi S (2011) Chemical constituents and biological activities of Iranian Artemisia species. Phytochem Lett 4:440–7

    Article  CAS  Google Scholar 

  25. Cheriti A, Rouissat A, Sekkoum K, et al (1995) Plantes de la pharmacopée traditionnelle dans la région d’El Bayadh (Algérie). Fitoterapia 525–38

    Google Scholar 

  26. Dif MM, Benali Toumi F, Benyahia M, Bouazza S (2015) Influence of solvent concentration on the extraction of phenolic compound and antioxidant activity of 2 lavenders from Benisaf region. Adv in Nat Appl Sci 3:7–10

    Google Scholar 

  27. Dif MM, Benali Toumi F, Benyahia M, Mekhfi N (2015) Optimization of extraction in Daphne gnidium L. leaves. Adv in Nat Appl Sci 3:5–7

    Google Scholar 

  28. Dif MM, Benali Toumi F, Benyahia M, et al (2015) Optimisation of extraction of phenolic compound and antioxidants in Algerian Lavendula stoicha (Algeria, NW). Glob J Med Plant Res 3:7–12

    Google Scholar 

  29. Dif MM, Benchiha H, Mehdadi Z, et al (2015) Étude quantitative des polyphénols dans les différents organes de l’espèce Papaver rhoeas L. Phytothérapie 13:314–9

    Article  CAS  Google Scholar 

  30. Aiyegoro OA, Okoh AI (2010) Preliminary phytochemical screening and In vitro antioxidant activities of the aqueous extract of Helichrysum longifolium. DCBMC Complement Altern Med 10:21–5

    Article  Google Scholar 

  31. Saleh NAM, El-Negoumy SI, Abd-All MF, et al (1985) Flavonoid glycosides of Artemisia monosperma and Artemisia herba-alba. Phytochemistry 24:201–3

    Article  CAS  Google Scholar 

  32. Saleh NAM, El-Negoumy SI, Abou-Zaid MM (1987) Flavonoids of Artemisia judaica, Artemisia monosperma and Artemisia herba-alba. Phytochemistry 26:3059–64

    Article  CAS  Google Scholar 

  33. Erlund I (2004) Review of the flavonoïds quercetin, hesperetin, and naringenin. Dietary sources, bioactivities, bioavailability and epidemiology. Nutr Res 24:851–74

    CAS  Google Scholar 

  34. Nair MP, Mahajan S, Reynolds JL, et al (2006) The flavonoid quercetin inhibits proinflammatory cytokine (Tumor necrosis factor alpha) gene expression in normal peripheral mononuclear cells via modulation of the NF-B system. Clin Vaccine Immunol 13:319–28

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  35. Harborne JB, Williams CA (2000) Advances in flavonoids research since 1992. Phytochemistry 55:481–504

    Article  CAS  PubMed  Google Scholar 

  36. Hsu CL, Yen GC (2008) Phenolic compounds: Evidence for inhibitory effects against obesity and their underlying molecular signalling mechanisms. Mol Nutr Food Res 52:53–61

    Article  CAS  PubMed  Google Scholar 

  37. Peterson J, Dwyer J (1998) Flavonoids: dietary occurrence and biochemical activity. Nutr Res 18:1995–2018

    Article  CAS  Google Scholar 

  38. Zhang J, Shen Q, Lu JC, et al (2010) Phenolic compounds from the leaves of Cyclocarya paliurus (Batal.) Iljinskaja and their inhibitory activity against PTP1B. Food Chem 119:1491–96

    Article  CAS  Google Scholar 

  39. Ryu JH, Lee SJ, Kim MJ, et al (2011) Antioxidant and anticancer activities of Artemisia annua L. and determination of functional compounds. J Korean Food Sci Nutr 40:509–16

    Article  CAS  Google Scholar 

  40. Kang KM, Lee SH (2013) Effects of extraction methods on the antioxidative activity of Artemisia sp. J Korean Soc Food Sci Nutr 42:1249–54

    Article  CAS  Google Scholar 

  41. Ali N, Shah I, Shah SW, et al (2013) Antioxidant and relaxant activity of fractions of crude methanol extract and essential oil of Artemisia macrocephala Jacquem. BMC Complement Altern Med 13:1–8

    Article  Google Scholar 

  42. Khlifi D, Sghaier RM, Amouri S, et al (2013) Composition and anti-oxidant, anti-cancer, and anti-inflammatory activities of Artemisia herba-alba, Ruta chalpensis L. and Peganum harmala L. Food Chem Toxicol 55:202–28

    Article  CAS  Google Scholar 

  43. Hatami T, Emami SA, Miraghaee SS, et al (2014) Total phenolic contents and antioxidant activities of different extracts and fractions from the aerial parts of Artemisia biennis willd. Iran J Pharm Res 13:551–8

    CAS  PubMed  PubMed Central  Google Scholar 

  44. Qian YX, Kang JC, Lei L, et al (2014) Screening and taxonomic identification of endophytic fungi with antitumor and antioxidant activities from Artemisia lactiflora. China J Chin Materia Medica 39:438–41

    Google Scholar 

  45. Chen L, Vigneault C, Raghavan GSV, et al (2007) Importance of the phytochemical content of fruits and vegetables to human health. Stewart Posthar Rev 3:2–9

    Article  Google Scholar 

  46. Cakir A, Mavi A, Yildirim A, Duru ME, et al (2003) Isolation and characterization of antioxidant phenolic compounds from the aerial parts of Hypericum hyssopifolium L. by activityguided fractionation. J Ethnopharmacol 87:73–83

    Article  CAS  Google Scholar 

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Correspondence to S. Bouazza.

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Dif, M.M., Benali Toumi, F., Boukaaza, H. et al. Phenolic content and antioxidant activity of Artemisa herba-alba, a medicinal plant from Algerian arid zone. Phytothérapie (2016). https://doi.org/10.1007/s10298-016-1077-9

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  • DOI: https://doi.org/10.1007/s10298-016-1077-9

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