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Cardiovascular complications in patients with autonomic failure

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Abstract

Patients with autonomic failure are characterized by orthostatic hypotension, supine hypertension, high blood pressure variability, blunted heart rate variability, and often have a “non-dipping” or “reverse dipping” pattern on 24-h ambulatory blood pressure monitoring. These alterations may lead to cardiovascular and cerebrovascular changes, similar to the target organ damage found in hypertension. Often patients with autonomic failure are on treatment with anti-hypotensive drugs, which may worsen supine hypertension. The aim of this review is to summarize the evidence for cardiac, vascular, renal, and cerebrovascular damage in patients with autonomic failure.

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On behalf of all authors, the corresponding author states that there is no conflict of interest.

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Authors and Affiliations

  1. Autonomic Unit and Hypertension Unit, Department of Medical Sciences, University of Torino, Torino, Italy

    Valeria Milazzo, Cristina Di Stefano, Alberto Milan, Agnese Ravera, Gabriele Sobrero, Luca Sabia, Franco Veglio & Simona Maule

  2. SCU Medicina 4, Azienda Ospedaliera “Città della Salute e della Scienza”, Corso Bramante 88, 10126, Torino, Italy

    Valeria Milazzo

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  1. Valeria Milazzo
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Milazzo, V., Di Stefano, C., Milan, A. et al. Cardiovascular complications in patients with autonomic failure. Clin Auton Res 25, 133–140 (2015). https://doi.org/10.1007/s10286-015-0275-0

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