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Catecholamines 101

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Abstract

This review of clinical catecholamine neurochemistry is based on the Streeten Memorial Lecture at the 19th annual meeting of the American Autonomic Society and lectures at a satellite of the 6th Congress of the International Society of Autonomic Neuroscience. Here I provide historical perspective, describe sources and meanings of plasma levels of catecholamines and their metabolites, present a model of a sympathetic noradrenergic neuron that conveys how particular aspects of sympathetic nervous function affect plasma levels of catecholamines and their metabolites, and apply the model to understand plasma neurochemical patterns associated with some drugs and disease states.

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  1. Clinical Neurocardiology Section, Clinical Neurosciences Program, Division of Intramural Research, National Institute of Neurological Disorders and Stroke, National Institutes of Health, 10 Center Drive MSC-1620, 9000 Rockville Pike, Bldg. 10 Rm. 5N220, Bethesda, MD, 20892, USA

    David S. Goldstein

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Goldstein, D.S. Catecholamines 101. Clin Auton Res 20, 331–352 (2010). https://doi.org/10.1007/s10286-010-0065-7

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