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Basal Contributions to Short-Latency Transient-Evoked Otoacoustic Emission Components

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Abstract

The presence of short-latency (SL), less compressive-growing components in bandpass-filtered transient-evoked otoacoustic emission (TEOAE) waveforms may implicate contributions from cochlear regions basal to the tonotopic place. Recent empirical work suggests a region of SL generation between ∼1/5 and 1/10-octave basal to the TEOAE frequency’s tonotopic place. However, this estimate may be biased to regions closer to the tonotopic place as the TEOAE extraction technique precluded measurement of components with latencies shorter than ∼5 ms. Using a variant of the non-linear, double-evoked extraction paradigm that permitted extraction of components with latencies as early as 1 ms, the current study empirically estimated the spatial-extent of the cochlear region contributing to 2 kHz SL TEOAE components. TEOAEs were evoked during simultaneous presentation of a suppressor stimulus, in order to suppress contributions to the TEOAE from different places along the cochlear partition. Three or four different-latency components of similar frequency content (∼2 kHz) were identified for most subjects. Component latencies ranged from 1.4 to 9.6 ms; latency was predictive of the component’s growth rate and the suppressor frequency to which the component’s magnitude was most sensitive to change. As component latency decreased, growth became less compressive and suppressor-frequency sensitivity shifted to higher frequencies. The shortest-latency components were most sensitive to suppressors approximately 3/5-octave higher than their nominal frequency of 2 kHz. These results are consistent with a distributed region of generation extending to approximately 3/5-octave basal to the TEOAE frequency’s tonotopic place. The empirical estimates of TEOAE generation are similar to model-based estimates where generation of the different-latency components occurs through linear reflection from impedance discontinuities distributed across the cochlear partition.

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Acknowledgments

Subject compensation was provided by a grant from the Executive Council for Graduate and Professional Students at the University of Iowa. The authors thank Rachel Stanziola and Brittany James who performed the data collection for this study. Portions of this work were presented at the 2013 Annual Meeting of the American Auditory Society and the 2014 Mid-winter Meeting of the Association for Research in Otolaryngology. This research served as part of the first author’s dissertation work at the University of Iowa.

COI Disclosure Statement

Neither of the authors have a commercial interest or other conflict of interest concerning the research detailed in the submitted manuscript. Funds for data collection (subject compensation) were provided by a grant from the Executive Council for Graduate and Professional Students at the University of Iowa.

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  1. Boys Town National Research Hospital, 555 North 30th Street, Omaha, NE, 68131, USA

    James D. Lewis

  2. Department of Communication Sciences and Disorders, University of Iowa, 250 Hawkins Drive, Iowa City, IA, 52242, USA

    Shawn S. Goodman

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  1. James D. Lewis
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Correspondence to James D. Lewis.

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Lewis, J.D., Goodman, S.S. Basal Contributions to Short-Latency Transient-Evoked Otoacoustic Emission Components. JARO 16, 29–45 (2015). https://doi.org/10.1007/s10162-014-0493-5

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