References
Vaidya DC, Schwartz RA, Janniger CK (2007) Nevus spilus. Cutis 80(6):465–468
Zayour M, Bolognia JL, Lazova R (2012) Multiple Spitz nevi: a clinicopathologic study of 9 patients. J Am Acad Dermatol 67(3):451–458, 458 e451-452. doi:10.1016/j.jaad.2011.11.941
Torti DC, Brennick JB, Storm CA, Dinulos JG (2011) Spitz nevi arising in speckled lentiginous nevus: clinical, histologic, and molecular evaluation of two cases. Pediatr Dermatol 28(5):561–567. doi:10.1111/j.1525-1470.2011.01239.x
Johr RH, Binder M (2000) Management of nevus spilus—a better way. Pediatr Dermatol 17(6):491–492
Kar H, Gupta L (2013) Treatment of nevus spilus with Q switched Nd:YAG laser. Indian J Dermatol Venereol Leprol 79(2):243–245. doi:10.4103/0378-6323.107650
Meesters AA, Wind BS, Kroon MW, Wolkerstorfer A, van der Veen JP, Nieuweboer-Krobotova L, van der Wal AC, Bos JD, Beek JF (2011) Ablative fractional laser therapy as treatment for Becker nevus: a randomized controlled pilot study. J Am Acad Dermatol 65(6):1173–1179. doi:10.1016/j.jaad.2010.07.049
Kagami S, Asahina A, Watanabe R, Mimura Y, Shirai A, Hattori N, Watanabe T, Tamaki K (2007) Treatment of 153 Japanese patients with Q-switched alexandrite laser. Lasers Med Sci 22(3):159–163
Grevelink JM, González S, Bonoan R, Vibhagool C, Gonzalez E (1997) Treatment of nevus spilus with the Q-switched ruby laser. Dermatol Surg 23(5):365–369
Gold MH, Foster TD, Bell MW (1999) Nevus spilus successfully treated with an intense pulsed light source. Dermatol Surg 25(3):254–255
Jiang X, Ge H, Zhou C et al (2014) The role of transforming growth factor beta1 in fractional laser resurfacing with a carbon dioxide laser. Lasers Med Sci 29(2):681–687
Acknowledgements
We thank the individuals and their families who participated in this project. We also thank Prof. Dough Zhang for his English grammar editing. This work was supported by the Natural Science Fund of Anhui Province (NO1608085MH194).
Author information
Authors and Affiliations
Corresponding authors
Ethics declarations
Ethics statement
All experiments were conducted and approved in accordance with the guidelines of the Institutional Ethics Committee at Anhui Medical University and adhered to the Declaration of Helsinki. After explaining the detailed procedures of treatment and the possible adverse events to the patient or surrogate, each gave informed consent.
Conflict of interest
The authors declare that they have no conflicts of interest.
Additional information
Mingjun Tang, Yuyan Cheng and Chunjun Yang contributed equally to this work.
Rights and permissions
About this article
Cite this article
Tang, M., Cheng, Y., Yang, C. et al. Nevus spilus: treatment with fractional CO2 laser in combination with MedLite C6 laser: a preliminary study. Lasers Med Sci 32, 1659–1662 (2017). https://doi.org/10.1007/s10103-016-2128-z
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s10103-016-2128-z