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Experimental research on laser interference micro/nano fabrication of hydrophobic modification of stent surface

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Abstract

Coronary artery disease (CAD) has become one of the important causes of human death, and coronary stent implantation is one of the most effective methods for the treatment of CAD. But the current clinical treatment has a high long-term restenosis rate and is easy to form late stent thrombosis. In order to solve these problems, coronary artery stent surface was directly modified by laser interference lithography and the highly ordered concave structures were fabricated. The morphology and contact angle (CA) of the microstructure were measured with scanning electron microscopy (SEM) and CA system. The water repellent property of the stent was also evaluated by the method of contacting the water drop with the stent and then separating. The result showed that the close-packed concave structure with the period of about 12.194 μm can be fabricated on the stent surface under special parameters (laser energy density of 3.5 J/cm−2, incident angles of 3°, exposure time of 80 s) by the three-beam laser interference of 1064 nm and the form structure has good water repellency with contact angle of 120°.

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Acknowledgements

This work was fully funded by the National Natural Science Foundation of China (Grant No. 81470024).

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Authors and Affiliations

  1. The Second Hospital of Jilin University, Changchun, 130041, China

    Junnan Wang & Bin Liu

  2. School of Optoelectronic Engineering, Changchun University of Science and Technology, Changchun, 130022, China

    Longyue Gao & Yongliang Li

  3. No. 218 Ziqiang St., Changchun, Jilin, 130021, People’s Republic of China

    Bin Liu

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  1. Junnan Wang
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  2. Longyue Gao
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  3. Yongliang Li
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  4. Bin Liu
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Correspondence to Bin Liu.

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The authors have no conflict of interests to declare. The work described has not been submitted elsewhere for publication in whole or in part, and all the authors listed have approved the manuscript. We further confirm that the order of authors listed in the manuscript has been approved by all of us.

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Wang, J., Gao, L., Li, Y. et al. Experimental research on laser interference micro/nano fabrication of hydrophobic modification of stent surface. Lasers Med Sci 32, 221–227 (2017). https://doi.org/10.1007/s10103-016-2105-6

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  • DOI: https://doi.org/10.1007/s10103-016-2105-6

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