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Relationship between lifestyle choices and hyperuricemia in Chinese men and women

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Abstract

We aimed to explore correlations between lifestyle choices and hyperuricemia in a large Chinese population, emphasizing the differences from opposite sex. Ten thousand four hundred fifty subjects were randomly recruited from Tianjin municipality in China. Hyperuricemia was defined as serum uric acid >420 μmol/L for men and >360 μmol/L for women. Demographic data, highest education degree, work type, commuting means, smoking and drinking status, exercise frequency, and quantitative assessments of dietary factors were collected. Anthropometric measurements and fasting blood tests were performed. Statistical analyses were conducted. Total hyperuricemic prevalence was 12.89 %, with male significantly higher than female. Body mass index, waist circumference, serum indices, and age displayed high correlation coefficients, and most lifestyle factors also showed significant correlations as well. Binary logistic regression models showed odds ratio of developing hyperuricemia were much greater in males than in females by eating habits. However, physical activity-related lifestyle choices tended to cast much greater influences on the likelihood of hyperuricemia in females. Lifestyle choices and hyperuricemia are closely related. For males, eating habits have greater influences on the likelihood of developing hyperuricemia. For females, lifestyle factors like work type, commuting method, and exercise have such effects.

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Acknowledgments

This investigation was supported by Tianjin Science and Technology Committee Foundation grants 11ZCGYSY05700 and 10JCZDJC19000, China National Natural Science Foundation grant 30900376, Tianjin Medical University Scientific Research grant 2008KY20, and Tianjin Medical University New Century Excellent Talent Program (awarded to Zhaowei Meng).

Young and Middle-aged Innovative Talent Training Program from Tianjin Education Committee (awarded to Zhaowei Meng).

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Authors and Affiliations

  1. Department of Health Management, Tianjin Medical University General Hospital, Tianjin, People’s Republic of China

    Li Liu, Qing Zhang & Kun Song

  2. Journal Press Center, Tianjin Normal University, Tianjin, People’s Republic of China

    Shanshan Lou

  3. Tianjin Key Laboratory of Lung Cancer Metastasis and Tumor Microenviroment, Tianjin Lung Cancer Institute, Tianjin, People’s Republic of China

    Ke Xu

  4. Department of Nuclear Medicine, Tianjin Medical University General Hospital, Anshan Road No. 154, Heping District, 300052, Tianjin, People’s Republic of China

    Zhaowei Meng

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  1. Li Liu
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  2. Shanshan Lou
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  3. Ke Xu
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  4. Zhaowei Meng
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  5. Qing Zhang
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  6. Kun Song
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Correspondence to Zhaowei Meng.

Additional information

Li Liu and Shanshan Lou as co-first authors contributed equally in this paper.

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Liu, L., Lou, S., Xu, K. et al. Relationship between lifestyle choices and hyperuricemia in Chinese men and women. Clin Rheumatol 32, 233–239 (2013). https://doi.org/10.1007/s10067-012-2108-z

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  • DOI: https://doi.org/10.1007/s10067-012-2108-z

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