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Radiological aid to clinical diagnosis of Schnitzler’s syndrome: multimodality imaging approach

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Abstract

Schnitzler’s syndrome is a rare combination of chronic urticaria, fever of unknown origin, disabling bone pain, and monoclonal gammopathy. We report a case with an unusual radiological manifestation as a solitary sclerotic lesion of the right iliac bone. Its main features on conventional radiography, computed tomography, and magnetic resonance imaging are described, and the main radiological differential diagnoses are discussed to help with the characterization of this syndrome, which requires a combination of clinical, laboratory, and radiological data. On the other hand, although our patient had an excellent clinical response to anakinra, the sclerotic lesion remained unchanged on follow-up X-ray examinations.

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Authors and Affiliations

  1. Department of Diagnostic Radiology, Faculty of Medicine, University Hospital “Marqués de Valdecilla” (HUMV), University of Cantabria, Avda. Valdecilla no. 25, 39008, Santander, Cantabria, Spain

    Alejandro Fernández Flórez, Elena Gallardo Agromayor, Rosario García-Barredo, Rosa Ma Landeras Alvaro & Ma Antonia Fernández Echevarría

  2. Department of Diagnostic Radiology, Hospital of Basurto, Bilbao, Spain

    Miren Gorriño Angulo

  3. Department of Rheumatology, Faculty of Medicine, HUMV, University of Cantabria, Santander, Spain

    Victor Manuel Martínez-Taboada

Authors
  1. Alejandro Fernández Flórez
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  2. Elena Gallardo Agromayor
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  3. Rosario García-Barredo
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  4. Rosa Ma Landeras Alvaro
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  5. Miren Gorriño Angulo
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  6. Victor Manuel Martínez-Taboada
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  7. Ma Antonia Fernández Echevarría
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Corresponding author

Correspondence to Alejandro Fernández Flórez.

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Flórez, A.F., Gallardo Agromayor, E., García-Barredo, R. et al. Radiological aid to clinical diagnosis of Schnitzler’s syndrome: multimodality imaging approach. Clin Rheumatol 27, 107–110 (2008). https://doi.org/10.1007/s10067-007-0758-z

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  • DOI: https://doi.org/10.1007/s10067-007-0758-z

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