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Huge Fetal Sacrococcygeal Teratoma with a Completely Formed Eye and Intratumoral DNA Ploidy Heterogeneity

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Pediatric and Developmental Pathology

ABSTRACT

Preterm infants and newborns with sacrococcygeal teratomas are at high risk for prenatal and perinatal complications. The prognosis depends on size and histology of the tumor, degree of prematurity, associated malformations, route of delivery, and prompt and complete surgical removal. Virtually any tissue can be present in a sacrococcygeal teratoma, but to date, ocular lens has been documented only as lentinoids (lens-like cells), whereas flow-cytometric data have been variably interpreted. We describe a case of a sacrococcygeal teratoma in an infant of 29 weeks gestational age that is remarkable for the weight (4500 g), the presence of a completely formed eye, and intratumoral DNA ploidy heterogeneity.

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Authors and Affiliations

  1. Institute of Pathology, University of Heidelberg, Im Neuenheimer Feld 220/221, D-69120 Heidelberg, Germany , , , , , , DE

    Consolato Sergi, Volker Ehemann & Herwart F. Otto

  2. Departments of Pediatrics and Neonatology, University of Heidelberg, Im Neuenheimer Feld 150, D-69120 Heidelberg, Germany , , , , , , DE

    Bernhard Beedgen & Otwin Linderkamp

Authors
  1. Consolato Sergi
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  2. Volker Ehemann
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  3. Bernhard Beedgen
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  4. Otwin Linderkamp
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  5. Herwart F. Otto
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Additional information

Received October 10, 1997; accepted January 21, 1998.

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Sergi, C., Ehemann, V., Beedgen, B. et al. Huge Fetal Sacrococcygeal Teratoma with a Completely Formed Eye and Intratumoral DNA Ploidy Heterogeneity. Pediatr. Dev. Pathol. 2, 50–57 (1999). https://doi.org/10.1007/s100249900089

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  • DOI: https://doi.org/10.1007/s100249900089

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