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Brown tumor of secondary hyperparathyroidism: surgical approach and clinical outcome

  • Case Report
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Oral and Maxillofacial Surgery Aims and scope Submit manuscript

Abstract

Background

Secondary hyperparathyroidism is a frequent complication of chronic renal failure. The brown tumor is an unusual presentation of fibrous osteitis that represents a serious complication of renal osteodystrophy, affecting predominantly the hands, feet, skull, and facial bones.

Case report

The aim of this paper is to describe the case of a 53-year-old female patient, with renal failure who has been on dialysis for 6 years and developed severe secondary hyperparathyroidism and brown tumor of the maxilla and mandible, confirmed by incisional biopsy. Parathyroidectomy was indicated as a result of rapid growth of the tumor and the maintenance of laboratory findings. Despite the normalization of serum parathyroid hormone and alkaline phosphatase, tumor regression was slow and patient’s important functional and esthetic deficits persisted. Excision of the mandible tumor was conservative. Osteoplasty was recommended because during a 5-year follow-up there was regression of the lesion, decreased pain, bleeding, and tooth mobility.

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Authors and Affiliations

  1. Federal University of Bahia, Salvador, Brazil

    Isaac Vieira Queiroz, Samara Pereira Queiroz, Rodolfo Bonfim Ribeiro & Iêda Margarida Crusoé-Rebello

  2. Federal University of Pernambuco, Recife, Brazil

    Rui Medeiros Jr. & Jair Carneiro Leão

Authors
  1. Isaac Vieira Queiroz
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  2. Samara Pereira Queiroz
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  3. Rui Medeiros Jr.
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  4. Rodolfo Bonfim Ribeiro
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  5. Iêda Margarida Crusoé-Rebello
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  6. Jair Carneiro Leão
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Correspondence to Isaac Vieira Queiroz.

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Queiroz, I.V., Queiroz, S.P., Medeiros, R. et al. Brown tumor of secondary hyperparathyroidism: surgical approach and clinical outcome. Oral Maxillofac Surg 20, 435–439 (2016). https://doi.org/10.1007/s10006-016-0575-0

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  • DOI: https://doi.org/10.1007/s10006-016-0575-0

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