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Radiotherapy does not impair dentin adhesive properties in head and neck cancer patients

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Abstract

Objectives

This study evaluated the influence of radiotherapy on the dentin bond strength of teeth extracted from patients who had undergone head and neck radiotherapy.

Materials and methods

A total of 36 samples were divided into two experimental groups: group I (control group, n = 18) and group II (in vivo irradiated group, n = 18). Groups I and II were further separated into three subgroups (six specimens per subgroup), which were further assigned to the three adhesive system protocols employed: Single Bond 2 (SB) (3M ESPE), Easy Bond (EB) (3M ESPE) and Clearfil SE Bond (CSE) (Kuraray). The adhesive systems were applied to the prepared surface according to the manufacturers’ instructions and restored using composite resin (Filtek Supreme, 3M ESPE). After 24 h in deionised water (37oC), teeth were horizontally and vertically cut to obtain beam specimens with a cross-section area of 0.8 ± 1.0 mm2. Specimens were tested in tension using a universal testing machine at a cross-speed of 0.5 mm/min. Fracture patterns were observed under SEM. Data was analysed by two-way analysis of variance (p ≤ 0.05).

Results

No statistically significant difference was found between the irradiated (R/SB = 44.66 ± 10.12 MPa; R/EB = 41.48 ± 12.71 MPa; and R/CSE = 46.01 ± 6.98 MPa) and control group (C/SB = 39.12 ± 9.51 MPa; C/EB = 42.40 ± 6.66 MPa; and C/CSE = 36.58 ± 7.06 MPa) for any of the adhesive systems. All groups presented a predominance of mixed fracture modes.

Conclusion

Head and neck radiotherapy did not affect dentin bond strength for the adhesive materials tested in this study.

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Acknowledgments

The authors would like to gratefully acknowledge the financial support of CAPES (Coordination of Improvement of Higher Level), and CNPq Proc. # 307540/2009-06.

Conflict of interest

The authors declare that they have no conflict of interest.

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Authors and Affiliations

  1. Department of Restorative Dentistry, Piracicaba Dental School, University of Campinas—UNICAMP, Limeira Avenue, 901-Piracicaba, São Paulo, Brazil, 13414-903, 52

    Roberta Galetti, Alberto Nogueira da Gama Antunes & Mario Fernando de Goes

  2. Department of Oral Diagnosis (Semiology Area), Piracicaba Dental School, University of Campinas—UNICAMP, Limeira Avenue, 901-Piracicaba, São Paulo, Brazil, 13414-903

    Alan Roger Santos-Silva & Marcio Ajudarte Lopes

  3. Head of the Department of Oral Medicine, A.C. Camargo Cancer Center, Rua Prof. Antônio Prudente, 211-São Paulo, São Paulo, Brazil, 01509-900

    Fabio de Abreu Alves

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  1. Roberta Galetti
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  2. Alan Roger Santos-Silva
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  3. Alberto Nogueira da Gama Antunes
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  4. Fabio de Abreu Alves
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  5. Marcio Ajudarte Lopes
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  6. Mario Fernando de Goes
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Corresponding author

Correspondence to Mario Fernando de Goes.

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Galetti, R., Santos-Silva, A.R., Nogueira da Gama Antunes, A. et al. Radiotherapy does not impair dentin adhesive properties in head and neck cancer patients. Clin Oral Invest 18, 1771–1778 (2014). https://doi.org/10.1007/s00784-013-1155-4

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  • DOI: https://doi.org/10.1007/s00784-013-1155-4

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