Correlation between hand/wrist and panoramic radiographs in severe secondary hyperparathyroidism
Rent the article at a discountRent now
* Final gross prices may vary according to local VAT.Get Access
Hand/wrist and dental radiographs are important for osteoporosis analysis in secondary hyperparathyroidism (SHPT). This study evaluated whether a correlation exists between the effects of the disease on the hands and jaws, and investigated the association between osteoporosis progression in the hands and parathyroid hormone (PTH) levels in chronic kidney disease (CKD) patients.
Materials and methods
Four panoramic radiographic parameters (mental index, mandibular cortical index, trabecular bone pattern, and calcification/resorption) and four corresponding hand/wrist radiographic parameters (metacarpal cortical thickness, phalangeal cortical index, trabecular bone pattern, and calcification/resorption) were applied to investigate possible correlation between the effects of SHPT on the jaws and hands/wrists, by Spearman's correlation coefficient. PTH levels and the hand/wrist radiographic parameters were also tested by spearman's correlation coefficient (p < 0.05). The presence of brown tumors, vascular calcifications, and acroosteolysis on the hands was also evaluated.
Mandibular cortical index was strongly correlated with the phalangeal cortical index (p = 0.000). Phalangeal cortical index and trabecular bone pattern of hand/wrist correlated with PTH levels (0.002 and 0.000, respectively). Brown tumors occurred in four CKD patients, while both vascular calcifications and acroosteolysis were observed in 19 patients.
There is a significant correlation between the morphological changes caused by secondary hyperparathyroidism in hand and jaw bones. The morphological status can be assessed using the mandibular cortical index, besides the phalangeal cortical index. The latter correlates well with parathyroid hormone levels of advanced chronic kidney disease.
Panoramic images reveal morphological changes in the jaw bone, indicating likewise changes in the hand/wrist in severe secondary hyperparathyroidism. The severity of the bone changes may be a reflection of the parathyroid hormone levels in advanced chronic kidney disease.
- Correlation between hand/wrist and panoramic radiographs in severe secondary hyperparathyroidism
Clinical Oral Investigations
Volume 17, Issue 6 , pp 1611-1617
- Cover Date
- Print ISSN
- Online ISSN
- Additional Links
- Secondary hyperparathyroidism
- Carpal bones
- Panoramic radiography
- Parathyroid hormone
- Kidney diseases
- Industry Sectors
- Author Affiliations
- 1. Department of Diagnosis and Surgery, School of Dentistry, UNESP—Univ Estadual Paulista, São José dos Campos, São Paulo, Brazil
- 4. Disciplina de Radiologia Odontológica da Faculdade de Odontologia, Universidade Estadual Paulista “Júlio de Mesquita Filho”, campus de São José dos Campos–Avenida Engenheiro Francisco José Longo, nº 777—Bairro: Jardim São Dimas, CEP: 12245-000, São Paulo, Brazil
- 2. Oral Imaging Center, School of Dentistry, Oral Pathology and Maxillofacial Surgery, Leuven, Belgium
- 3. Department of Oral Diagnosis and Bioscience, School of Dentistry, UNESP—Univ Estadual Paulista, São José dos Campos, São Paulo, Brazil