Skip to main content

Advertisement

Log in

Oral health in patients on haemodialysis for diabetic nephropathy and chronic glomerulonephritis

  • Original Article
  • Published:
Clinical Oral Investigations Aims and scope Submit manuscript

Abstract

Objective

The objective of this study was to clarify differences in oral health status between patients who needed haemodialysis (HD) owing to diabetic nephropathy (DN) and chronic glomerulonephritis (CGN).

Materials and methods

Ninety-eight HD patients who were 50–70 years old were selected as the study subjects [DN group (29 subjects) and CGN group (69 subjects)] to compare with 106 control subjects (control group) not undergoing HD. All HD subjects underwent oral- and systemic-related examination just before HD therapy.

Results

The mean number of teeth present in the DN group was significantly less than in the CGN and control groups. The mean percentage of sites with bleeding on probing in the DN group was greater than in the CGN and control groups. The mean salivary flow rate in the DN and CGN groups was significantly lower compared with the control group.

Conclusion

The patients undergoing HD for DN were found to have fewer teeth and worse periodontal health compared with those undergoing HD for CGN and with the control subjects not undergoing HD. Furthermore, the dental and periodontal health of the patients undergoing HD for CGN was comparable to that of the controls.

Clinical relevance

For effective measures of prevention and improvement of oral health in HD patients, clinicians should be aware of the differences in the characteristics of the oral health between patients undergoing HD for DN and CGN.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Winearls C (2003) Clinical evaluation and manifestation of chronic renal failure. In: Johnson RJ, Feehally J (eds) Comprehensive clinical nephrology, 2nd edn. Mosby, New York, pp 857–872

    Google Scholar 

  2. Rivin AU, Yoshino J, Shickman M, Schjeide OA (1958) Serum cholesterol measurement; hazards in clinical interpretation. J Am Med Assoc 166:2108–2111

    Article  PubMed  Google Scholar 

  3. Akmal M (2001) Hemodialysis in diabetic patients. Am J Kidney Dis 38:S195–S199

    Article  PubMed  Google Scholar 

  4. Iseki K, Shinzato T, Nagura Y, Akiba T (2004) Factors influencing long-term survival in patients on chronic dialysis. Clin Exp Nephrol 8:89–97

    PubMed  Google Scholar 

  5. Epstein SR, Mandel I, Scopp IW (1980) Salivary composition and calculus formation in patients undergoing hemodialysis. J Periodontol 51:336–338

    Article  PubMed  Google Scholar 

  6. Kho HS, Lee SW, Chung SC, Kim YK (1999) Oral manifestations and salivary flow rate, pH, and buffer capacity in patients with end-stage renal disease undergoing hemodialysis. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 88:316–319

    Article  PubMed  Google Scholar 

  7. Klassen JT, Krasko BM (2002) The dental health status of dialysis patients. J Can Dent Assoc 68:34–38

    PubMed  Google Scholar 

  8. Guzeldemir E, Toygar HU, Tasdelen B, Torun D (2009) Oral health-related quality of life and periodontal health status in patients undergoing hemodialysis. J Am Dent Assoc 140:1283–1293

    PubMed  Google Scholar 

  9. Ziebolz D, Fischer P, Hornecker E, Mausberg RF (2012) Oral health of hemodialysis patients: a cross-sectional study at two German dialysis centers. Hemodial Int 16:69–75

    Google Scholar 

  10. Frankenthal S, Nakhoul F, Machtei EE, Green J, Ardekian L, Laufer D, Peled M (2002) The effect of secondary hyperparathyroidism and hemodialysis therapy on alveolar bone and periodontium. J Clin Periodontol 29:479–483

    Article  PubMed  Google Scholar 

  11. Marakoglu I, Gursoy UK, Demirer S, Sezer H (2003) Periodontal status of chronic renal failure patients receiving hemodialysis. Yonsei Med J 44:648–652

    PubMed  Google Scholar 

  12. Duran I, Erdemir EO (2004) Periodontal treatment needs of patients with renal disease receiving haemodialysis. Int Dent J 54:274–278

    Article  PubMed  Google Scholar 

  13. Bayraktar G, Kazancioglu R, Bozfakioglu S, Yildiz A, Ark E (2004) Evaluation of salivary parameters and dental status in adult hemodialysis patients. Clin Nephrol 62:380–383

    PubMed  Google Scholar 

  14. Bots CP, Poorterman JH, Brand HS, Kalsbeek H, van Amerongen BM, Veerman EC, Nieuw Amerongen AV (2006) The oral health status of dentate patients with chronic renal failure undergoing dialysis therapy. Oral Dis 12:176–180

    Article  PubMed  Google Scholar 

  15. Bayraktar G, Kurtulus I, Duraduryan A, Cintan S, Kazancioglu R, Yildiz A, Bural C, Bozfakioglu S, Besler M, Trablus S, Issever H (2007) Dental and periodontal findings in hemodialysis patients. Oral Dis 13:393–397

    Article  PubMed  Google Scholar 

  16. Chuang SF, Sung JM, Kuo SC, Huang JJ, Lee SY (2005) Oral and dental manifestations in diabetic and nondiabetic uremic patients receiving hemodialysis. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 99:689–695

    Article  PubMed  Google Scholar 

  17. Awano S, Ansai T, Takata Y, Soh I, Yoshida A, Hamasaki T, Kagiyama S, Nakamichi I, Sonoki K, Takehara T (2008) Relationship between volatile sulfur compounds in mouth air and systemic disease. J Breath Res 2:017012

    Article  PubMed  Google Scholar 

  18. Eigner TL, Jastak JT, Bennett WM (1986) Achieving oral health in patients with renal failure and renal transplants. J Am Dent Assoc 113:612–616

    PubMed  Google Scholar 

  19. De Rossi SS, Glick M (1996) Dental considerations for the patient with renal disease receiving hemodialysis. J Am Dent Assoc 127:211–219

    PubMed  Google Scholar 

  20. Al-Wahadni A, Al-Omari MA (2003) Dental diseases in a Jordanian population on renal dialysis. Quintessence Int 34:343–347

    PubMed  Google Scholar 

  21. Bayraktar G, Kurtulus I, Kazancioglu R, Bayramgurler I, Cintan S, Bural C, Bozfakioglu S, Besler M, Trablus S, Issever H, Yildiz A (2008) Evaluation of periodontal parameters in patients undergoing peritoneal dialysis or hemodialysis. Oral Dis 14:185–189

    Article  PubMed  Google Scholar 

  22. Pucher J, Stewart J (2004) Periodontal disease and diabetes mellitus. Curr Diab Rep 4:46–50

    Article  PubMed  Google Scholar 

  23. Patino Marin N, Loyola Rodriguez JP, Medina Solis CE, Pontigo Loyola AP, Reyes Macias JF, Ortega Rosado JC, Aradillas Garcia C (2008) Caries, periodontal disease and tooth loss in patients with diabetes mellitus types 1 and 2. Acta Odontol Latinoam 21:127–133

    PubMed  Google Scholar 

  24. Kaur G, Holtfreter B, Rathmann W, Schwahn C, Wallaschofski H, Schipf S, Nauck M, Kocher T (2009) Association between type 1 and type 2 diabetes with periodontal disease and tooth loss. J Clin Periodontol 36:765–774

    Article  PubMed  Google Scholar 

  25. Tanwir F, Altamash M, Gustafsson A (2009) Effect of diabetes on periodontal status of a population with poor oral health. Acta Odontol Scand 67:129–133

    Article  PubMed  Google Scholar 

  26. Bergstrom J (2004) Tobacco smoking and chronic destructive periodontal disease. Odontology 92:1–8

    Article  PubMed  Google Scholar 

  27. Do LG, Slade GD, Roberts-Thomson KF, Sanders AE (2008) Smoking-attributable periodontal disease in the Australian adult population. J Clin Periodontol 35:398–404

    Article  PubMed  Google Scholar 

  28. Chambrone L, Chambrone D, Lima LA, Chambrone LA (2010) Predictors of tooth loss during long-term periodontal maintenance: a systematic review of observational studies. J Clin Periodontol 37:675–684

    Article  PubMed  Google Scholar 

  29. Willi C, Bodenmann P, Ghali WA, Faris PD, Cornuz J (2007) Active smoking and the risk of type 2 diabetes: a systematic review and meta-analysis. JAMA 298:2654–2664

    Article  PubMed  Google Scholar 

  30. Psaltopoulou T, Ilias I, Alevizaki M (2010) The role of diet and lifestyle in primary, secondary, and tertiary diabetes prevention: a review of meta-analyses. Rev Diabet Stud 7:26–35

    Article  PubMed  Google Scholar 

  31. Gerdin EW, Einarson S, Jonsson M, Aronsson K, Johansson I (2005) Impact of dry mouth conditions on oral health-related quality of life in older people. Gerodontology 22:219–226

    Article  PubMed  Google Scholar 

  32. Cho MA, Ko JY, Kim YK, Kho HS (2010) Salivary flow rate and clinical characteristics of patients with xerostomia according to its aetiology. J Oral Rehabil 37:185–193

    Article  PubMed  Google Scholar 

  33. Wiener RC, Wu B, Crout R, Wiener M, Plassman B, Kao E, McNeil D (2010) Hyposalivation and xerostomia in dentate older adults. J Am Dent Assoc 141:279–284

    PubMed  Google Scholar 

Download references

Acknowledgements

This research was supported by Kyushu Dental College. We would like to thank all those who participated in this study as well as the Kokura-Daiichi Hospital for their assistance and support

Conflict of interest

The authors declare that they have no conflicts of interest.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Shuji Awano.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Teratani, G., Awano, S., Soh, I. et al. Oral health in patients on haemodialysis for diabetic nephropathy and chronic glomerulonephritis. Clin Oral Invest 17, 483–489 (2013). https://doi.org/10.1007/s00784-012-0741-1

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00784-012-0741-1

Keywords

Navigation