Skip to main content
SpringerLink
Log in

Nitrite reduction by molybdoenzymes: a new class of nitric oxide-forming nitrite reductases

  • Minireview
  • Published:
JBIC Journal of Biological Inorganic Chemistry Aims and scope Submit manuscript

Abstract

Nitric oxide (NO) is a signalling molecule involved in several physiological processes, in both prokaryotes and eukaryotes, and nitrite is being recognised as an NO source particularly relevant to cell signalling and survival under challenging conditions. The “non-respiratory” nitrite reduction to NO is carried out by “non-dedicated” nitrite reductases, making use of metalloproteins present in cells to carry out other functions, such as several molybdoenzymes (a new class of nitric oxide-forming nitrite reductases). This minireview will highlight the physiological relevance of molybdenum-dependent nitrite-derived NO formation in mammalian, plant and bacterial signalling (and other) pathways. The mammalian xanthine oxidase/xanthine dehydrogenase, aldehyde oxidase, mitochondrial amidoxime-reducing component, plant nitrate reductase and bacterial aldehyde oxidoreductase and nitrate reductases will be considered. The nitrite reductase activity of each molybdoenzyme will be described and the review will be oriented to discuss the feasibility of the reactions from a (bio)chemical point of view. In addition, the molecular mechanism proposed for the molybdenum-dependent nitrite reduction will be discussed in detail.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5
Fig. 6
Fig. 7
Fig. 8

Similar content being viewed by others

Notes

  1. See the contributions of both Hu and Ribbe and Bjornsson, Neese, Schrock, Einsle and DeBeer in this JBIC issue.

  2. See Hille et al.’s contribution in this J Biol Inorg Chem issue.

  3. See Kappler and Enemark’s contribution in this J Biol Inorg Chem issue.

  4. See Ott et al.’s contribution in this J Biol Inorg Chem issue.

  5. Mammalian XO and XD are two forms of the same protein (same gene product). Mammalian XO enzymes are synthesised as an NAD+-dependent dehydrogenase form, the XD, and are believed to exist mostly as XD under normal physiological conditions [3, 27–32]. However, the XD form can be readily converted into a strict oxidase form, the XO. The only "functional" distinction between XD and XO lies in the electron acceptor used by each form: while XD transfers the electrons preferentially to NAD+, XO fails to react with NAD+ and uses exclusively dioxygen. During the XD into XO conversion process (through oxidation of cysteine residues or limited proteolysis), the protein conformation at the FAD centre is modified and this conformational alteration is responsible for the differentiated oxidising substrate specificity displayed by XO and XD [30, 230–237, 239, 242] (note that both dioxygen and NAD+ react at the FAD centre). On the other hand, the protein structure at the Fe/S and molybdenum centres is not changed during the conversion and, in accordance, the two enzyme forms, XO and XD, are virtually identical with respect to the binding and catalysis of substrates at the molybdenum centre [3, 27–30]. This is also the case of the nitrite reduction reaction that, as will be described, occurs at the molybdenum centre. For these reasons, XO and XD can be considered as one unique enzyme for the discussion of the overall structural organisation and molybdenum reactivity (reaction mechanism).

  6. Enzyme forms whose FAD centre was chemically removed.

  7. AFR, activity-to-flavin ratio, is a measure of the number of enzyme molecules with an intact molybdenum centre [3, 27–32, 230, 256].

  8. Enzyme form whose molybdenum sulpho group was chemically removed.

  9. Although in XD/XO/AO, the electrons consumption by dioxygen is made via the FAD centre.

  10. Because the enzyme does not catalyse the sulphite oxidation by molecular oxygen, a more appropriate name (Enzyme Nomenclature Commitee, IUBMB) would be sulphite oxidoreductase (SOR).

  11. See Kappler and Enemark’s contribution in this JBIC issue.

  12. Caused by the inability to synthesise the pyranopterin cofactor or certain point mutations.

  13. Presently, the structure of human SO is not known. However, because the sequence identity among the eukaryotic SO is very high, with 68 % identity (85 % similarity) between the chicken and human enzymes, the structure of chicken liver SO (Fig. 2b) is a good template for the human counterpart [321].

  14. Because SO is not regenerated during the nitrite reduction reaction (SO catalyses a single turnover reaction), the values above indicated as k cat and K m are better described as k electron transfer and K d values [333].

  15. NaR is highly regulated by complex transcriptional, translational and posttranslational mechanisms. The posttranslational regulation involves the phosphorylation of a serine residue in the linker region between the molybdenum and haem domains [413, 414]. The phosphorylation is catalysed by protein kinases, including AMP-activated [415] and calcium-dependent kinases [416]. This phosphorylation creates a recognition site that recruits a specific regulatory protein (one member of the 14-3-3 family), whose binding effectively inhibits the enzyme [417–419]. Thus, mutation of the key serine residue to an aspartate results in a plant that has the NaR always active [420–422]. In vivo, the NaR inactivation occurs rapidly in darkness or when carbon dioxide is removed. This posttranslational regulation is essential to lower the NaR activity at night, when photosynthetically generated reducing equivalents are not available to reduce nitrite to ammonia. In this way, the nocturnal nitrite levels would not increase to dangerous concentrations [423].

  16. Nitrite is promptly transported to the leaves’ chloroplasts or roots’ plastids, where it is rapidly reduced by SNIR, so that it does not accumulate.

  17. The inhibition of the photosynthetic electron flow causes nitrite accumulation, because its transport to the chloroplasts depends on the pH gradient across the chloroplast envelope (buildup by the photosynthetic activity). In addition, its reduction to ammonium is hindered in the absence of photosynthetically reduced ferredoxin [470, 471].

  18. The conversion of XD into an XO form is not common to all plants: while the enzyme from Arabidopsis thaliana does not have the two corresponding cysteine residues [479] involved in the conversion mechanism of the mammalian enzyme, the pea leaf peroxisomal enzyme was described to exist mainly (70 %) as an XO form [480–482].

  19. It should be noted that the eukaryotic assimilatory cytoplasmatic NaR (discussed above), belonging to the SO family, is distinct from any type of prokaryotic NaR.

  20. If nitrite was to bind to the oxidised molybdenum of XO, then its preliminary incubation in the enzyme reaction mixture, before the addition of xanthine or aldehyde, would modify the K m value of the reducing substrate relatively to add nitrite after the reducing substrate addition, which was not observed (parallel to competitive inhibition).

  21. In spite of the nitrite-binding mode in CuNiR being a "bidentate nitrito" mode, it is tempting not to follow all the similarities between the molybdenum- and copper-containing enzymes.

Abbreviations

AO:

Aldehyde oxidase

AOR:

Aldehyde oxidoreductases

CuNiR:

Copper-containing nitrite reductase (one of the enzymes responsible for the respiratory nitrite reduction to NO)

DMSOR:

Dimethylsulphoxide reductase

DPI:

Diphenyleneiodonium chloride

EPR:

Electron paramagnetic resonance spectroscopy

Fe/S:

Iron–sulphur centre

mARC:

Mammalian mitochondrial amidoxime-reducing component

MOSC:

From molybdenum cofactor sulphurase C-terminal domain (proteins involved in pyranopterin cofactor biosynthesis)

NaR:

Nitrate reductase (all types of nitrate reductase enzymes)

NiR:

Nitrite reductases (“dedicated” and “non-dedicated” enzymes)

NO:

Nitric oxide radical

NOS:

NO synthases

ROS:

Reactive oxygen species

SO:

Sulphite oxidase

SOD:

Superoxide dismutase

XD:

Xanthine dehydrogenase

XO:

Xanthine oxidase

References

  1. Zhang Y, Gladyshev VN (2008) J Mol Biol 379:881

    PubMed Central  CAS  PubMed  Google Scholar 

  2. Zhang Y, Rump S, Gladyshev VN (2011) Coord Chem Rev 2011(255):1206

    Google Scholar 

  3. Hille R (1995) Chem Rev 96:2757

    Google Scholar 

  4. Hille R (2002) Trends Biochem Sci 27:360

    CAS  PubMed  Google Scholar 

  5. Rothery RA, Workun GJ, Weiner JH (2008) Biochim Biophys Acta 1778:1897

    CAS  PubMed  Google Scholar 

  6. Schwarz G, Mendel R, Ribbe M (2009) Nature 460:839

    CAS  PubMed  Google Scholar 

  7. Hille R, Mendel R (2011) Coord Chem Rev 255:991

    CAS  Google Scholar 

  8. Mendel R, Kruse T (2012) Biochim Biophys Acta 1823:1568

    CAS  PubMed  Google Scholar 

  9. Hille R (2013) Dalton Trans 42:3029

    CAS  PubMed  Google Scholar 

  10. Hille R, Hall J, Basu P (2014) Chem Rev 114:3963

    CAS  PubMed  Google Scholar 

  11. Cvetkovic A, Menon AL, Thorgersen MP, Scott JW, Poole FL, Jenney FE, Lancaster WA, Praissman JL, Shanmukh S, Vaccaro BJ, Trauger SA, Kalisiak E, Apon JV, Siuzdak G, Yannone SM, Tainer JA, Adams MWW (2010) Nature 466:779

    CAS  PubMed  Google Scholar 

  12. Zhang Y, Gladyshev VN (2011) J Biol Chem 286:23623

    PubMed Central  CAS  PubMed  Google Scholar 

  13. Boal AK, Rosenzweig AC (2012) Science 337:1617

    PubMed  Google Scholar 

  14. Lukoyanov D, Yang ZY, Barney BM, Dean DR, Seefeldt LC, Hoffman BM (2012) Proc Natl Acad Sci USA 109:5583

    PubMed Central  CAS  PubMed  Google Scholar 

  15. Wiig JA, Hu Y, Lee CC, Ribbe MW (2012) Science 337:1672

    CAS  PubMed  Google Scholar 

  16. Hoffman BM, Lukoyanov D, Dean DR, Seefeldt LC (2013) Acc Chem Res 46:587

    PubMed Central  CAS  PubMed  Google Scholar 

  17. Feng C, Tollin G, Enemark JH (2007) Biochim Biophys Acta 1774:527

    PubMed Central  CAS  PubMed  Google Scholar 

  18. Loschi L, Brokx SJ, Hills TL, Zhang G, Bertero MG, Lovering AL, Weiner JH, Strynadka NCJ (2004) J Biol Chem 279:50391

    CAS  PubMed  Google Scholar 

  19. George GN, Doonan CJ, Rothery RA, Boroumand N, Weiner JH (2007) Inorg Chem 46:2

    CAS  PubMed  Google Scholar 

  20. Yang J, Rothery R, Sempombe J, Weiner JH, Kirk ML (2009) J Am Chem Soc 131:15612

    PubMed Central  CAS  PubMed  Google Scholar 

  21. Havelius KGV, Reschke S, Horn S, Doerlng A, Niks D, Hille R, Schulzke C, Leimkuehler S, Haumann M (2011) Inorg Chem 50:741

    CAS  PubMed  Google Scholar 

  22. Pushie MJ, Doonan CJ, Moquin K, Weiner JH, Rothery R, George GN (2011) Inorg Chem 50:732

    CAS  PubMed  Google Scholar 

  23. Hille R, Nishino T (1995) FASEB J 9:995

    CAS  PubMed  Google Scholar 

  24. Hille R (2005) Arch Biochem Biophys 433:107

    CAS  PubMed  Google Scholar 

  25. Hille R (2006) Eur J Inorg Chem 1913

  26. Nishino T, Okamoto K, Eger BT, Pai EF, Nishino T (2008) FEBS J 275:3278

    CAS  PubMed  Google Scholar 

  27. Hille R, Nishino T, Bittner F (2011) Coord Chem Rev 255:1179

    PubMed Central  CAS  PubMed  Google Scholar 

  28. Okamoto K, Kusano T, Nishino T (2013) Curr Pharm Des 19:2606

    PubMed Central  CAS  PubMed  Google Scholar 

  29. Johannes J, Unciuleac M, Friedrich T, Warkentin E, Ermler U, Boll M (2008) Biochemistry 47:4964

    CAS  PubMed  Google Scholar 

  30. Boll M (2005) Biochim Biophys Acta 1707:34

    CAS  PubMed  Google Scholar 

  31. Schink B (1985) Arch Microbiol 142:295

    CAS  Google Scholar 

  32. Messerschmidt A, Niessen H, Abt D, Einsle O, Schink B, Kroneck PM (2004) Proc Natl Acad Sci USA 101:11571

    PubMed Central  CAS  PubMed  Google Scholar 

  33. Jormakka M, Yokoyama K, Yano T, Tamakoshi M, Akimoto S, Shimamura T, Curmi P, Iwata S (2008) Nat Struct Mol Biol 15:730

    PubMed Central  CAS  PubMed  Google Scholar 

  34. Richardson DJ, Watmough NJ (1999) Curr Opin Chem Biol 3:207

    CAS  PubMed  Google Scholar 

  35. Galloway JN, Dentener FJ, Capone DG, Boyer EW, Howarth RW, Seitzinger SP, Asner GP, Cleveland CC, Green PA, Holland EA, Karl DM, Michaels AF, Porter JH, Townsend AR, Vorosmarty CJ (2004) Biogeochemistry 70:153

    CAS  Google Scholar 

  36. Bothe H, Ferguson SJ, Newton WE (2007) Biology of the Nitrogen Cycle. Elsevier, Amsterdam

    Google Scholar 

  37. Jetten MSM (2008) Environ Microbiol 10:2903

    CAS  PubMed  Google Scholar 

  38. Canfield DE, Glazer AN, Falkowski PG (2010) Science 330:192

    CAS  PubMed  Google Scholar 

  39. Martínez-Espinosa RM, Cole JA, Richardson DJ, Watmough NJ (2011) Biochem Soc Trans 39:175

    PubMed  Google Scholar 

  40. Fowler D, Coyle M, Skiba U, Sutton MA, Cape JN, Reis S, Sheppard LJ, Jenkins A, Grizzetti B, Galloway JN, Vitousek P, Leach A, Bouwman AF, Butterbach-Bahl K, Dentener F, Stevenson D, Amann M, Voss M (2013) Philos Trans R Soc B 368:164

    Google Scholar 

  41. Galloway JN, Leach AM, Bleeker A, Erisman JW (2013) Philos Trans R Soc B 368:120

    Google Scholar 

  42. Maia L, Moura JJG (2014) Chem Rev 114:5273

    CAS  PubMed  Google Scholar 

  43. Moncada S, Palmer RMJ, Higgs EA (1991) Pharmacol Rev 43:109

    CAS  PubMed  Google Scholar 

  44. Pfeiffer S, Mayer B, Hemmens B (1999) Angew Chem Int Ed 38:1714

    Google Scholar 

  45. Stuehr DJ (1999) Biochim Biophys Acta 1411:217

    CAS  PubMed  Google Scholar 

  46. Alderton WK, Cooper CE, Knowles RG (2001) Biochem J 357:593

    PubMed Central  CAS  PubMed  Google Scholar 

  47. Lehnert N, Berto TC, Galinato MGI, Goodrich LE (2011) In: Kadish KM, Smith KM, Guilard R (eds) The Handbook of Porphyrin Science. World Scientific, New York, pp 1–139

    Google Scholar 

  48. Beckman JS, Koppenol WH (1996) Am J Physiol 271:C1424

    CAS  PubMed  Google Scholar 

  49. Clementi E, Brown GC, Feelisch M, Moncada S (1998) Proc Natl Acad Sci USA 95:7631

    PubMed Central  CAS  PubMed  Google Scholar 

  50. Eiserich JP, Patel RP, O’Donnell VB (1998) Mol Aspects Med 19:221

    CAS  PubMed  Google Scholar 

  51. Feelisch M, Rassaf T, Mnaimneh S, Singh N, Bryan NS, Jourd’Heuil D, Kelm M (2002) FASEB J 16:1775

    CAS  PubMed  Google Scholar 

  52. Gaston BM, Carver J, Doctor A, Palmer LA (2003) Mol Interv 3:253

    CAS  PubMed  Google Scholar 

  53. Bryan NS, Rassaf T, Maloney RE, Rodriguez CM, Saijo F, Rodriguez JR, Feelisch M (2004) Proc Natl Acad Sci USA 101:4308

    PubMed Central  CAS  PubMed  Google Scholar 

  54. Liu L, Yan Y, Zeng M, Zhang J, Hanes MA, Ahearn G, McMahon TJ, Dickfeld T, Marshall HE, Que LG, Stamler JS (2004) Cell 116:617

    CAS  PubMed  Google Scholar 

  55. Lima B, Lam GK, Xie L, Diesen DL, Villamizar N, Nienaber J, Messina E, Bowles D, Kontos CD, Hare JM, Stamler JS, Rockman HA (2009) Proc Natl Acad Sci USA 106:6297

    PubMed Central  CAS  PubMed  Google Scholar 

  56. Sanghani PC, Davis WI, Fears SL, Green SL, Zhai L, Tang Y, Martin E, Bryan NS, Sanghani SP (2009) J Biol Chem 284:24354

    PubMed Central  CAS  PubMed  Google Scholar 

  57. Toledo JC Jr, Augusto O (2012) Chem Res Toxicol 25:975

    CAS  PubMed  Google Scholar 

  58. Wink DA, Darbyshire JF, Nims RW, Saavedra JE, Ford PC (1993) Chem Res Toxicol 6:23

    CAS  PubMed  Google Scholar 

  59. Goldstein S, Czapski G (1995) J Am Chem Soc 117:12078

    CAS  Google Scholar 

  60. Liu X, Liu Q, Gupta E, Zorko N, Brownlee E, Zweier JL (2005) Nitric Oxide 13:68

    CAS  PubMed  Google Scholar 

  61. Shiva S, Wang X, Ringwood LA, Xu X, Yuditskaya S, Annavajjhala V, Miyajima H, Hogg N, Harris ZL, Gladwin MT (2006) Nat Chem Biol 2:486

    CAS  PubMed  Google Scholar 

  62. Doyle MP, Hoekstra JW (1981) J Inorg Biochem 14:351

    CAS  PubMed  Google Scholar 

  63. Sharma VS, Taylor TG, Gardiner R (1987) Biochemistry 26:3837

    CAS  PubMed  Google Scholar 

  64. Eich RF, Li T, Lemon DD, Doherty DH, Curry SR, Aitken JF, Mathews AJ, Johnson KA, Smith RD Jr, Olson JS (1996) Biochemistry 35:6976

    CAS  PubMed  Google Scholar 

  65. Liu X, Miller MJS, Joshi MS, Sadowska-Krowicka H, Clark DA, Lancaster JR (1998) J Biol Chem 273:18709

    CAS  PubMed  Google Scholar 

  66. Gow AJ, Luchsinger BP, Pawloski JR, Singel DJ, Stamler JS (1999) Proc Natl Acad Sci USA 96:9027

    PubMed Central  CAS  PubMed  Google Scholar 

  67. Brunori M (2001) Trends Biochem Sci 26:21

    CAS  PubMed  Google Scholar 

  68. Flögel U, Merx MW, Gödecke A, Decking UKM, Schrader J (2001) Proc Natl Acad Sci USA 98:735

    PubMed Central  PubMed  Google Scholar 

  69. Huang K-T, Han TH, Hyduke DR, Vaughn MW, Herle HV, Hein TW, Zhang C, Kuo L, Liao JC (2001) Proc Natl Acad Sci USA 98:11771

    PubMed Central  CAS  PubMed  Google Scholar 

  70. Herold S, Exner M, Nauser T (2001) Biochemistry 40:3385

    CAS  PubMed  Google Scholar 

  71. Witting PK, Douglas DJ, Mauk AG (2001) J Biol Chem 276:3991

    CAS  PubMed  Google Scholar 

  72. Gardner PR, Gardner AM, Brashear WT, Suzuki T, Hvitved AN, Setchell KDR, Olson JS (2006) J Inorg Biochem 100:542

    CAS  PubMed  Google Scholar 

  73. Reichert ET, Mitchell SW (1988) Am J Med Sci 159:158

    Google Scholar 

  74. Dykhuizen RS, Fraser A, McKenzie H, Golden M, Leifert C, Benjamin N (1998) Gut 42:334

    PubMed Central  CAS  PubMed  Google Scholar 

  75. Gladwin MT, Shelhamer JH, Schechter AN, Pease-Fye ME, Waclawiw MA, Panza JA, Ognibene FP, Cannon RO III (2000) Proc Natl Acad Sci USA 97:11482

    PubMed Central  CAS  PubMed  Google Scholar 

  76. Phillips R, Kuijper S, Benjamin N, Wansbrough-Jones M, Wilks M, Kolk AH (2004) Antimicrob Agents Chemother 48:3130

    PubMed Central  CAS  PubMed  Google Scholar 

  77. Webb A, Bond R, McLean P, Uppal R, Benjamin N, Ahluwalia A (2004) Proc Natl Acad Sci USA 101:13683

    PubMed Central  CAS  PubMed  Google Scholar 

  78. Anyim M, Benjamin N, Wilks M (2005) Int J Antimicrob Agents 26:85

    CAS  PubMed  Google Scholar 

  79. Duranski MR, Greer JJ, Dejam A, Jaganmohan S, Hogg N, Langston W, Patel RP, Yet SF, Wang X, Kevil CG, Gladwin MT, Lefer DJ (2005) J Clin Investig 115:1232

    PubMed Central  CAS  PubMed  Google Scholar 

  80. Lu P, Liu F, Yao Z, Wang CY, Chen DD, Tian Y, Zhang JH, Wu YH (2005) Hepatobiliary Pancreas Dis Int 4:350

    CAS  Google Scholar 

  81. Jung KH, Chu K, Ko SY, Lee ST, Sinn DI, Park DK, Kim JM, Song EC, Kim M, Roh JK (2006) Stroke 37:2744

    CAS  PubMed  Google Scholar 

  82. Larsen FJ, Ekblom B, Sahlin K, Lundberg JO, Weitzberg E (2006) N Engl J Med 355:2792

    CAS  PubMed  Google Scholar 

  83. Rao A, Jump RL, Pultz NJ, Pultz MJ, Donskey CJ (2006) Antimicrob Agents Chemother 50:3901

    PubMed Central  CAS  PubMed  Google Scholar 

  84. Lefer D (2006) J Am J Physiol Renal Physiol 290:F777

    CAS  Google Scholar 

  85. Baker JE, Su J, Fu X, Hsu A, Gross GJ, Tweddell JS, Hogg N (2007) J Mol Cell Cardiol 43:437

    PubMed Central  CAS  PubMed  Google Scholar 

  86. Bryan NS, Calvert JW, Elrod JW, Gundewar S, Ji SY, Lefer DJ (2007) Proc Natl Acad Sci USA 104:19144

    PubMed Central  CAS  PubMed  Google Scholar 

  87. Dezfulian C, Raat N, Shiva S, Gladwin MT (2007) Cardiovasc Res 75:327

    PubMed Central  CAS  PubMed  Google Scholar 

  88. Oldfield EH, Cannon RO 3rd, Schechter AN, Gladwin MT (2007) Circulation 116:1821

    PubMed  Google Scholar 

  89. Tripatara P, Patel NS, Webb A, Rathod K, Lecomte FM, Mazzon E, Cuzzocrea S, Yaqoob MM, Ahluwalia A, Thiemermann C (2007) J Am Soc Nephrol 18:570

    CAS  PubMed  Google Scholar 

  90. Butler AR, Feelisch M (2008) Circulation 117:2151

    CAS  PubMed  Google Scholar 

  91. Gonzalez FM, Shiva S, Vincent PS, Ringwood LA, Hsu LY, Hon YY, Aletras AH, Cannon RO 3rd, Gladwin MT, Arai AE (2008) Circulation 117:2986

    PubMed Central  CAS  PubMed  Google Scholar 

  92. Hendgen-Cotta UB, Merx MW, Shiva S, Schmitz J, Becher S, Klare JP, Steinhoff H, Goedecke A, Schrader J, Gladwin MT, Kelm M, Rassaf T (2008) Proc Natl Acad Sci USA 105:10256

    PubMed Central  CAS  PubMed  Google Scholar 

  93. Lundberg JO, Weitzberg E, Gladwin MT (2008) Nat Rev Drug Discov 7:156

    CAS  PubMed  Google Scholar 

  94. Sinha SS, Shiva S, Gladwin MT (2008) Trends Cardiovasc Med 18:163

    CAS  PubMed  Google Scholar 

  95. Webb AJ, Milsom AB, Rathod KS, Chu WL, Qureshi S, Lovell MJ, Lecomte FM, Perrett D, Raimondo C, Khoshbin E, Ahmed Z, Uppal R, Benjamin N, Hobbs AJ, Ahluwalia A (2008) Circ Res 103:957

    PubMed Central  CAS  PubMed  Google Scholar 

  96. Calvert JW, Lefer DJ (2009) Cardiovasc Res 83:195

    PubMed Central  CAS  PubMed  Google Scholar 

  97. Casey DB, Badejo AM, Dhaliwal JS, Murthy SN, Hyman AL, Nossaman BD, Kadowitz PJ (2009) Am J Physiol Heart Circ Physiol 296:H524

    PubMed Central  CAS  PubMed  Google Scholar 

  98. Lefer DJ (2009) Arch Pharm Res 32:1127

    CAS  PubMed  Google Scholar 

  99. Lundberg JO, Gladwin MT, Ahluwalia A, Benjamin N, Bryan NS, Butler A, Cabrales P, Fago A, Feelisch M, Ford PC, Freeman BA, Frenneaux M, Friedman J, Kelm M, Kevil CG, Kim-Shapiro DB, Kozlov AV, Lancaster JR Jr, Lefer DJ, McColl K, McCurry K, Patel RP, Petersson J, Rassaf T, Reutov VP, Richter-Addo JB, Schechter A, Shiva S, Tsuchiya K, Faassen EE, Webb AJ, Zuckerbraun BS, Zweier JL, Weitzberg E (2009) Nat Chem Biol 5:865

    PubMed Central  CAS  PubMed  Google Scholar 

  100. Calvert JW, Lefer DJ (2010) Nitric Oxide 22:91

    PubMed Central  CAS  PubMed  Google Scholar 

  101. Ingram TE, Pinder AG, Bailey DM, Fraser AG, James PE (2010) Am J Physiol Heart Circ Physiol 298:H331

    PubMed Central  CAS  PubMed  Google Scholar 

  102. Jung KH, Chu K, Lee ST, Sunwoo JS, Park DK, Kim JH, Kim S, Lee SK, Kim M, Roh JK (2010) Biochem Biophys Res Commun 403:66

    CAS  PubMed  Google Scholar 

  103. Nossaman BD, Akuly HA, Lasker GF, Nossaman VE, Rothberg PA, Kadowitz PJ (2010) Asian J Exp Biol Sci 1:451

    PubMed Central  CAS  PubMed  Google Scholar 

  104. Zuckerbraun BS, Shiva S, Ifedigbo E, Mathier MA, Mollen KP, Rao J, Bauer PM, Choi JJ, Curtis E, Choi AM, Gladwin MT (2010) Circulation 121:98

    CAS  PubMed  Google Scholar 

  105. Gilchrist M, Shore AC, Benjamin N (2011) Cardiovasc Res 89:492

    CAS  PubMed  Google Scholar 

  106. Kevil CG, Kolluru GK, Pattillo CB, Giordano T (2011) Free Radic Biol Med 51:576

    CAS  PubMed  Google Scholar 

  107. Larsen FJ, Schiffer TA, Borniquel S, Sahlin K, Ekblom B, Lundberg JO, Weitzberg E (2011) Cell Metab 13:149

    CAS  PubMed  Google Scholar 

  108. Lundberg JO, Carlstrom M, Larsen FJ, Weitzberg E (2011) Cardiovasc Res 89:525

    CAS  PubMed  Google Scholar 

  109. Machha A, Schechter AN (2011) Eur J Nutr 50:293

    PubMed Central  CAS  PubMed  Google Scholar 

  110. Murillo D, Kamga C, Mo L, Shiva S (2011) Nitric Oxide 25:70

    PubMed Central  CAS  PubMed  Google Scholar 

  111. Pattillo CB, Bir S, Rajaram V, Kevil CG (2011) Cardiovasc Res 89:533

    PubMed Central  CAS  PubMed  Google Scholar 

  112. Sindler AL, Fleenor BS, Calvert JW, Marshall KD, Zigler ML, Lefer DJ, Seals DR (2011) Aging Cell 10:429

    PubMed Central  CAS  PubMed  Google Scholar 

  113. Baliga RS, Milsom AB, Ghosh SM, Trinder SL, Macallister RJ, Ahluwalia A, Hobbs AJ (2012) Circulation 125:2922

    PubMed Central  CAS  PubMed  Google Scholar 

  114. Sparacino-Watkins CE, Lai YC, Gladwin MT (2012) Ther Circ 125:2824

    Google Scholar 

  115. Bueno M, Wang J, Mora AL, Gladwin MT (2013) Antioxid Redox Signal 18:1797

    PubMed Central  CAS  PubMed  Google Scholar 

  116. Cantu-Medellin N, Kelley EE (2013) Nitric Oxide 34:19

    PubMed Central  CAS  PubMed  Google Scholar 

  117. Ghosh SM, Kapil V, Fuentes-Calvo I, Bubb KJ, Pearl V, Milsom AB, Khambata R, Maleki-Toyserkani S, Yousuf M, Benjamin N, Webb AJ, Caulfield MJ, Hobbs AJ, Ahluwalia A (2013) Hypertension 61:1091

    CAS  PubMed  Google Scholar 

  118. Helms C, Kim-Shapiro DB (2013) Free Radical Biol Med 61:464

    CAS  Google Scholar 

  119. Kim-Shapiro DB, Gladwin MT (2014) Nitric Oxide 38:58

    CAS  PubMed  Google Scholar 

  120. Omar SA, Webb A (2014) J Mol Cell Cardiol 73:57

    CAS  PubMed  Google Scholar 

  121. Duranski MR, Greer JJ, Dejam A, Jaganmohan S, Hogg N, Langston W, Patel RP, Yet SF, Wang X, Kevil CG, Gladwin MT, Lefer DJ (2005) J Clin Invest 115:1232

    PubMed Central  CAS  PubMed  Google Scholar 

  122. Cosby K, Partovi KS, Crawford JH, Patel RP, Reiter CD, Martyr S, Yang BK, Waclawiw MA, Zalos G, Xu X, Huang KT, Shields H, Kim-Shapiro DB, Schechter AN, Cannon RO III, Gladwin MT (2003) Nat Med 9:1498

    CAS  PubMed  Google Scholar 

  123. Crawford JH, Isbell TS, Huang Z, Shiva S, Chacko BK, Schechter AN, Darley-Usmar VM, Kerby JD, Lang JD Jr, Kraus D, Ho C, Gladwin MT, Patel RP (2006) Blood 107:566

    PubMed Central  CAS  PubMed  Google Scholar 

  124. Kumar D, Branch BG, Pattillo CB, Hood J, Thoma S, Simpson S, Illum S, Arora N, Chidlow JH Jr, Langston W, Teng X, Lefer DJ, Patel RP, Kevil CG (2008) Proc Natl Acad Sci USA 105:7540

    PubMed Central  CAS  PubMed  Google Scholar 

  125. Cauwels A, Buys ES, Thoonen R, Geary L, Delanghe J, Shiva S, Brouckaert P (2009) J Exp Med 206:2915

    PubMed Central  CAS  PubMed  Google Scholar 

  126. Bryan NS, Fernandez BO, Bauer SM, Garcia-Saura MF, Milsom AB, Rassaf T, Maloney RE, Bharti A, Rodriguez J, Feelisch M (2005) Nat Chem Biol 1:290

    CAS  PubMed  Google Scholar 

  127. Castello PR, David PS, McClure T, Crook Z, Poyton RO (2006) Cell Metab 3:277

    CAS  PubMed  Google Scholar 

  128. Larsen FJ, Weitzberg E, Lundberg JO, Ekblom B (2007) Acta Physiol 191:59

    CAS  Google Scholar 

  129. Shiva S, Huang Z, Grubina R, Sun J, Ringwood LA, MacArthur PH, Xu X, Murphy E, Darley-Usmar VM, Gladwin MT (2007) Circ Res 100:654

    CAS  PubMed  Google Scholar 

  130. Larsen FJ, Weitzberg E, Lundberg JO, Ekblom B (2010) Free Radical Biol Med 48:342

    CAS  Google Scholar 

  131. Shiva S (2010) Nitric Oxide 22:64

    PubMed Central  CAS  PubMed  Google Scholar 

  132. Benamar A, Rolletschek H, Borisjuk L, Avelange-Macherel M-H, Curien G, Mostefai HA, Andriantsitohaina R, Macherel D (2008) Biochim Biophys Acta 1777:1268

    CAS  PubMed  Google Scholar 

  133. Gautier C, van Faassen E, Mikula I, Martasek P, Slama-Schwok A (2006) Biochem Biophys Res Commun 341:816

    CAS  PubMed  Google Scholar 

  134. Li H, Liu X, Cui H, Chen YR, Cardounel AJ, Zweier JL (2006) J Biol Chem 281:12546

    CAS  PubMed  Google Scholar 

  135. Vanin AF, Bevers LM, Slama-Schwok A, van Faassen EE (2006) Cell Mol Life Sci 64:96

    Google Scholar 

  136. Basu S, Azarova NA, Font MD, King SB, Hogg N, Gladwin MT, Shiva S, Kim-Shapiro DB (2008) J Biol Chem 283:32590

    PubMed Central  CAS  PubMed  Google Scholar 

  137. Castello PR, Woo DK, Ball K, Wojcik J, Liu L, Poyton RO (2008) Proc Natl Acad Sci USA 105:8203

    PubMed Central  CAS  PubMed  Google Scholar 

  138. Hendrychova T, Anzenbacherova E, Hudecek J, Skopalik J, Lange R, Hildebrandt P, Otyepka M, Anzenbacher P (2011) Biochim Biophys Acta 1814:58

    CAS  PubMed  Google Scholar 

  139. Nelson DR (2011) Biochim Biophys Acta 1814:14

    CAS  PubMed  Google Scholar 

  140. Tiso M, Tejero J, Basu S, Azarov I, Wang X, Simplaceanu V, Frizzell S, Jayaraman T, Geary L, Shapiro C, Ho C, Shiva S, Kim-Shapiro DB, Gladwin MT (2011) J Biol Chem 286:18277

    PubMed Central  CAS  PubMed  Google Scholar 

  141. Li H, Hemann C, Abdelghany TM, El-Mahdy MA, Zweier JL (2012) J Biol Chem 287:36623

    PubMed Central  CAS  PubMed  Google Scholar 

  142. Haldane J (1901) J Hyg 1:115

    PubMed Central  CAS  PubMed  Google Scholar 

  143. Brooks J (1937) Proc R Soc London Ser B 123:368

    CAS  Google Scholar 

  144. Doyle MP, Pickering RA, DeWeert TM, Hoekstra JW, Pater D (1981) J Biol Chem 256:12393

    CAS  PubMed  Google Scholar 

  145. Sulc F, Immoos CE, Pervitsky D, Farmer PJ (2004) J Am Chem Soc 126:1096

    CAS  PubMed  Google Scholar 

  146. Huang Z, Shiva S, Kim-Shapiro DB, Patel RP, Ringwood LA, Irby CE, Huang KT, Ho C, Hogg N, Schechter AN, Gladwin MT (2005) J Clin Invest 115:2099

    PubMed Central  CAS  PubMed  Google Scholar 

  147. Rassaf T, Flogel U, Drexhage C, Hendgen-Cotta U, Kelm M, Schrader J (2007) Circ Res 100:1749

    CAS  PubMed  Google Scholar 

  148. Gladwin MT, Kim-Shapiro DB (2008) Blood 112:2636

    PubMed Central  CAS  PubMed  Google Scholar 

  149. Salhany JM (2008) Biochemistry 47:6059

    CAS  PubMed  Google Scholar 

  150. Shiva S, Rassaf T, Patel RP, Gladwin MT (2011) Cardiovasc Res 89:566

    PubMed Central  CAS  PubMed  Google Scholar 

  151. Kozlov AV, Staniek K, Nohl H (1999) FEBS Lett 454:127

    CAS  PubMed  Google Scholar 

  152. Nohl H, Staniek K, Sobhian B, Bahrami S, Redl H, Kozlov AV (2000) Acta Biochim Pol 47:913

    CAS  PubMed  Google Scholar 

  153. Aamand R, Dalsgaard T, Jensen FB, Simonsen U, Roepstorff A, Fago A (2009) Am J Physiol Heart Circ Physiol 297:H2068

    CAS  PubMed  Google Scholar 

  154. Badejo AM Jr, Hodnette C, Dhaliwal JS, Casey DB, Pankey E, Murthy SN, Nossaman BD, Hyman AL, Kadowitz P (2010) J Am J Physiol Heart Circ Physiol 2010(299):H819

    Google Scholar 

  155. Garattini E, Fratelli M, Terao M (2008) Cell Mol Life Sci 65:1019

    CAS  PubMed  Google Scholar 

  156. Pryde DC, Dalvie D, Hu Q, Jones P, Obach RS, Tran TD (2010) J Med Chem 53:8441

    CAS  PubMed  Google Scholar 

  157. Garattini E, Terao M (2011) Drug Metab Rev 43:374

    CAS  PubMed  Google Scholar 

  158. Swenson TL, Casida JE (2013) Toxicol Sci 133:22

    CAS  PubMed  Google Scholar 

  159. Murray KN, Chaykin S (1966) J Biol Chem 241:3468

    CAS  PubMed  Google Scholar 

  160. Landon EJ, Myles M (1967) Biochim Biophys Acta 143:429

    CAS  PubMed  Google Scholar 

  161. Massey V, Brumby PE, Komai H, Palmer G (1969) J Biol Chem 244:1682

    CAS  PubMed  Google Scholar 

  162. Krenitsky TA, Neil SM, Elion GB, Hitchings GH (1972) Arch Biochem Biophys 150:585

    CAS  PubMed  Google Scholar 

  163. Morpeth FF (1983) Biochim Biophys Acta 744:328

    CAS  PubMed  Google Scholar 

  164. Hall WW, Krenitsky TA (1986) Arch Biochem Biophys 251:36

    CAS  PubMed  Google Scholar 

  165. Janssen M, Tavenier M, Koster JF, de Jong JW (1993) Biochim Biophys Acta 1156:307

    CAS  PubMed  Google Scholar 

  166. Mira L, Maia L, Barreira L, Manso CF (1995) Arch Biochem Biophys 318:53

    CAS  PubMed  Google Scholar 

  167. Maia L, Vala A, Mira L (2005) Free Radical Res 39:979

    CAS  Google Scholar 

  168. Maia L, Duarte RO, Ponces-Freire A, Moura JJG, Mira L (2007) J Biol Inorg Chem 12:777

    CAS  PubMed  Google Scholar 

  169. Kundu TK, Velayutham M, Zweier JL (2012) Biochemistry 51:2930

    PubMed Central  CAS  PubMed  Google Scholar 

  170. Suzuki YJ, Forman HJ, Sevanian A (1997) Free Radic Biol Med 22:269

    CAS  PubMed  Google Scholar 

  171. Stone JR, Yang S (2006) Antioxid Redox Signal 8:243

    CAS  PubMed  Google Scholar 

  172. Veal EA, Day AM, Morgan BA (2007) Mol Cell 26:1

    CAS  PubMed  Google Scholar 

  173. Granger DN, Rutili G, McCord JM (1981) Gastroenterology 81:22

    CAS  PubMed  Google Scholar 

  174. McCord JM (1985) N Engl J Med 312:159

    CAS  PubMed  Google Scholar 

  175. Granger DN, Hollwarth ME, Parks DA (1986) Acta Physiol Scand 548:47

    CAS  Google Scholar 

  176. Hearse DJ, Manning AS, Downey JM, Yellon DM (1986) Acta Physiol Scand 548:65

    CAS  Google Scholar 

  177. Lieber CS (1988) N Engl J Med 319:1639

    CAS  PubMed  Google Scholar 

  178. Zweier JL, Kuppusamy P, Lutty GA (1988) Proc Natl Acad Sci USA 85:4046

    PubMed Central  CAS  PubMed  Google Scholar 

  179. Cederbaum AI (1989) Free Radical Biol Med 7:537

    CAS  Google Scholar 

  180. Kato S, Kawase T, Alderman J, Inatomi N, Lieber C (1990) Gastroenterology 98:203

    CAS  PubMed  Google Scholar 

  181. Nordmann R, Ribière C, Rouach H (1992) Free Radical Biol Med 12:219

    CAS  Google Scholar 

  182. Nishino T (1994) J Biochem 116:1

    CAS  PubMed  Google Scholar 

  183. Zweier JL, Broderick R, Kuppusamy P, Thompson-Gorman S, Lutty GA (1994) J Biol Chem 269:24156

    CAS  PubMed  Google Scholar 

  184. Harrison R (1997) Biochem Soc Trans 25:786

    CAS  PubMed  Google Scholar 

  185. Nishino T, Nakanishi S, Okamoto K, Mizushima J, Hori H, Iwasaki T, Nishino T, Ichimori K, Nakazawa H (1997) Biochem Soc Trans 25:783

    CAS  PubMed  Google Scholar 

  186. Wright RM, Repine JE (1997) Biochem Soc Trans 25:799

    CAS  PubMed  Google Scholar 

  187. Beckman KB, Ames BN (1998) Physiol Rev 78:547

    CAS  PubMed  Google Scholar 

  188. Zhang Z, Blake DR, Stevens CR, Kanczler JM, Winyard PG, Symons MC, Benboubetra M, Harrison R (1998) Free Radic Res 28:151

    CAS  PubMed  Google Scholar 

  189. Suzuki H, Delano FA, Parks DA, Jamshidi N, Granger DN, Ishii H, Suematsu M, Zweifach BW, Schmid-Schonbein GW (1998) Proc Natl Acad Sci USA 95:4754

    PubMed Central  CAS  PubMed  Google Scholar 

  190. Wright RM, McManaman JL, Repine JE (1999) Free Radic Biol Med 26:348

    CAS  PubMed  Google Scholar 

  191. Harrison R (2002) Free Radic Biol Med 33:774

    CAS  PubMed  Google Scholar 

  192. Wu D, Cederbaum AI (2003) Alcohol Res Health 27:277

    PubMed  Google Scholar 

  193. Stirpe F, Ravaioli M, Battelli MG, Musiani S, Grazi GL (2002) Am J Gastroenterol 97:2079

    CAS  PubMed  Google Scholar 

  194. Berry CE, Hare JM (2004) J Physiol 555:589

    PubMed Central  CAS  PubMed  Google Scholar 

  195. Small DM, Coombes JS, Bennett N, Johnson DW, Gobe GC (2012) Nephrology 17:311

    CAS  PubMed  Google Scholar 

  196. Bachschmid MM, Schildknecht S, Matsui R, Zee R, Haeussler D, Cohen RA, Pimental D, Loo B (2013) Ann Med 45:17

    PubMed Central  CAS  PubMed  Google Scholar 

  197. Madamanchi NR, Runge MS (2013) Free Radic Biol Med 61:473

    CAS  PubMed  Google Scholar 

  198. Della Corte E, Gozzetti G, Novello F, Stirpe F (1969) Biochim Biophys Acta 191:164

    CAS  PubMed  Google Scholar 

  199. Jarasch ED, Grund C, Bruder G, Heid HW, Keenan TW, Franke WW (1981) Cell 25:67

    CAS  PubMed  Google Scholar 

  200. Parks DA, Granger DN (1986) Acta Physiol Scand Suppl 548:87

    CAS  PubMed  Google Scholar 

  201. Beedham C (1987) Prog Med Chem 24:85

    CAS  PubMed  Google Scholar 

  202. Ichikawa M, Nishino T, Ichikawa A (1992) J Histochem Cytochem 40:1097

    CAS  PubMed  Google Scholar 

  203. Moriwaki Y, Yamamoto T, Yamaguchi K, Takahashi S, Higashino K (1996) Histochem Cell Biol 105:71

    CAS  PubMed  Google Scholar 

  204. Sarnesto A, Linder N, Raivio KO (1996) Lab Invest 74:48

    CAS  PubMed  Google Scholar 

  205. Linder N, Rapola J, Raivio KO (1999) Lab Invest 79:967

    CAS  PubMed  Google Scholar 

  206. Marti R, Varela E, Pascual C, Segura RM (2001) Clin Chim Acta 303:117

    CAS  PubMed  Google Scholar 

  207. Adachi T, Fukushima T, Usami Y, Hirano K (1993) Biochem J 289:523

    PubMed Central  CAS  PubMed  Google Scholar 

  208. Fukushima T, Adachi T, Hirano K (1995) Biol Pharm Bull 18:156

    CAS  PubMed  Google Scholar 

  209. White CR, Darley-Usmartt V, Berrington WR, Mcadams M, Gore JZ, Thompsont JA, Parkst DA, Tarpeyt MM, Freemant BA (1996) Proc Natl Acad Sci USA 93:8745

    PubMed Central  CAS  PubMed  Google Scholar 

  210. Radi R, Rubbo H, Bush K, Freeman BA (1997) Arch Biochem Biophys 339:125

    CAS  PubMed  Google Scholar 

  211. Rouquette M, Page S, Bryant R, Benboubetra M, Stevens CR, Blake DR, Whish WD, Harrison R, Tosh D (1998) FEBS Lett 426:397

    CAS  PubMed  Google Scholar 

  212. Vickers S, Schiller HJ, Hildreth JE, Bulkley GB (1998) Surgery 124:551

    CAS  PubMed  Google Scholar 

  213. Houston M, Estevez A, Chumley P, Aslan M, Marklundi S, Parks DA, Freeman BA (1999) J Biol Chem 274:4985

    CAS  PubMed  Google Scholar 

  214. Kelley EE, Hock T, Khoo NK, Richardson GR, Johnson KK, Powell PC, Giles GI, Agarwal A, Lancaster JR Jr, Tarpey MM (2006) Free Radic Biol Med 40:952

    CAS  PubMed  Google Scholar 

  215. Turner NA, Doyle WA, Ventom AM, Bray RC (1995) Eur J Biochem 232:646

    CAS  PubMed  Google Scholar 

  216. Saito T, Nishino T (1989) J Biol Chem 264:10015

    CAS  PubMed  Google Scholar 

  217. Amaya Y, Yamazaki K, Sato M, Noda K, Nishino T (1990) J Biol Chem 265:14170

    CAS  PubMed  Google Scholar 

  218. Nishino T, Nishino T (1997) J Biol Chem 272:29859

    CAS  PubMed  Google Scholar 

  219. Harris CM, Massey V (1997) J Biol Chem 272:8370

    CAS  PubMed  Google Scholar 

  220. Enroth C, Eger BT, Okamoto K, Nishino T, Nishino T, Pai EF (2000) Proc Natl Acad Sci USA 97:10723

    PubMed Central  CAS  PubMed  Google Scholar 

  221. Nishino T, Okamoto K, Kawaguchi Y, Hori H, Matsumura T, Eger BT, Pai EF, Nishino T (2005) J Biol Chem 280:24888

    CAS  PubMed  Google Scholar 

  222. Tsujii A, Nishino T (2008) Nucleosides Nucleotides Nucleic Acids 27:881

    CAS  PubMed  Google Scholar 

  223. Ishikita H, Eger BT, Okamoto K, Nishino T, Pai EF (2012) J Am Chem Soc 134:999

    PubMed Central  CAS  PubMed  Google Scholar 

  224. Kooij A, Schiller HJ, Schijns M, Van Noorden CJ, Frederiks WM (1994) Hepatology 19:1488

    CAS  PubMed  Google Scholar 

  225. Okamoto K, Matsumoto K, Hille R, Eger BT, Pai EF, Nishino T (2004) Proc Natl Acad Sci USA 101:7931

    PubMed Central  CAS  PubMed  Google Scholar 

  226. Doonan CJ, Stockert A, Hille R, George GN (2005) J Am Chem Soc 127:4518

    CAS  PubMed  Google Scholar 

  227. Coelho C, Mahro M, Trincão J, Carvalho ATP, Ramos MJ, Terao M, Garattini E, Leimkühler S, Romaao MJ (2012) J Biol Chem 287:40690

    PubMed Central  CAS  PubMed  Google Scholar 

  228. Kuwabara Y, Nishino T, Okamoto K, Matsumura T, Eger BT, Pai EF, Nishino T (2003) Proc Natl Acad Sci USA 100:8170

    PubMed Central  CAS  PubMed  Google Scholar 

  229. Pauff JM, Zhang J, Bell CE, Hille R (2008) J Biol Chem 283:4818

    CAS  PubMed  Google Scholar 

  230. Millar TM, Stevens CR, Benjamin N, Eisenthal R, Harrison R, Blake DR (1998) FEBS Lett 427:225

    CAS  PubMed  Google Scholar 

  231. Zhang Z, Naughton D, Winyard PG, Benjamin N, Blake DR, Symons MC (1998) Biochem Biophys Res Commun 249:767

    CAS  PubMed  Google Scholar 

  232. Godber HLJ, Doel JJ, Sapkota GP, Blake DR, Stevens CR, Eisenthal R, Harrison R (2000) J Biol Chem 275:7757

    CAS  PubMed  Google Scholar 

  233. Li H, Samouilov A, Liu X, Zweier JL (2001) J Biol Chem 276:24482

    CAS  PubMed  Google Scholar 

  234. Li H, Samouilov A, Liu X, Zweier JL (2004) J Biol Chem 279:16939

    CAS  PubMed  Google Scholar 

  235. Li H, Cui H, Kundu TK, Alzawahra W, Zweier JL (2008) J Biol Chem 283:17855

    PubMed Central  CAS  PubMed  Google Scholar 

  236. Maia L, Moura JJG (2011) J Biol Inorg Chem 16:443

    CAS  PubMed  Google Scholar 

  237. Maia L, Pereira V, Mira L, Moura JJG (2014) Nitrite reductase activity of rat and human xanthine oxidase, xanthine dehydrogenase and aldehyde oxidase: evaluation of their contribution to the NO formation in vivo. Biochemistry. doi:10.1021/bi500987w

  238. Li H, Kundu TK, Zweier JL (2009) J Biol Chem 284:33850

    PubMed Central  CAS  PubMed  Google Scholar 

  239. Massey V, Komai H, Palmer G, Elion GB (1970) J Biol Chem 245:2837

    CAS  PubMed  Google Scholar 

  240. Hawkes TR, George G, Bray RC (1984) Biochem J 218:961

    PubMed Central  CAS  PubMed  Google Scholar 

  241. Okamoto K, Egerb BT, Nishino T, Pai EF, Nishino T (2008) Nucleos Nucleot Nucleic Acid 27:888

    CAS  Google Scholar 

  242. Branzoli U, Massey V (1974) J Biol Chem 249:4346

    CAS  PubMed  Google Scholar 

  243. Opie LH (1976) Circ Res 38:152

    Google Scholar 

  244. Cobbe SM, Poole-Wilson PA (1980) J Mol Cell Cardiol 12:761

    CAS  PubMed  Google Scholar 

  245. Momomura S, Ingwall JS, Parker JA, Sahagian P, Ferguson JJ, Grossman W (1985) Circ Res 57:822

    CAS  PubMed  Google Scholar 

  246. Zweier JL, Wang P, Samouilov A, Kuppusamy P (1995) Nat Med 1:804

    CAS  PubMed  Google Scholar 

  247. Samouilov A, Kuppusamy P, Zweier JL (1998) Arch Biochem Biophys 357:1

    CAS  PubMed  Google Scholar 

  248. Zweier JL, Samouilov A, Kuppusamy P (1999) Biochim Biophys Acta 1411:250

    CAS  PubMed  Google Scholar 

  249. Modin A, Björne H, Herulf M, Alving K, Weitzberg E, Lundberg JO (2001) Acta Physiol Scand 171:9

    CAS  PubMed  Google Scholar 

  250. Gorenflo M, Zheng C, Poge A, Bettendorf M, Werle E, Fiehn W (2001) Clin Lab 47:441

    CAS  PubMed  Google Scholar 

  251. Rodriguez J, Maloney RE, Rassaf T, Bryan NS, Feelisch M (2003) Proc Natl Acad Sci USA 100:336

    PubMed Central  CAS  PubMed  Google Scholar 

  252. Shiva S, Gladwin MT (2009) J Mol Cell Cardiol 46:1

    CAS  PubMed  Google Scholar 

  253. Millar TM (2004) FEBS Lett 562:129

    CAS  PubMed  Google Scholar 

  254. Ward JPT (2008) Biochim Biophys Acta 1777:1

    CAS  PubMed  Google Scholar 

  255. Williamson JR, Steenbergen C, Rich T, Deleeuw G, Barlow C, Chance B (1977) In: Lefer AM, Kelliher GJ, Rovetto MJ (eds) Pathophysiology and therapeutics of myocardial ischemia. SPECTRUM Publications Inc, New York, pp 193–225

  256. Kobayashi K, Neely JR (1983) J Mol Cell Cardiol 15:359

    CAS  PubMed  Google Scholar 

  257. Williamson JR (1996) J Biol Chem 241:5026

    Google Scholar 

  258. Varadarajan SG, Novalija E, Smart SC, Stowe DF (2001) Am J Physiol 280:H280

    CAS  Google Scholar 

  259. Zhou L, Stanley WC, Saidel GM, Yu X, Cabrera ME (2005) J Physiol 569:925

    PubMed Central  CAS  PubMed  Google Scholar 

  260. Lartigue-Mattei C, Chabard JL, Bargnoux H, Petit J, Berger JA, Ristori JM, Bussiere JL, Catilina P, Catilina MJ (1990) J Chromatogr 529:93

    CAS  PubMed  Google Scholar 

  261. Himmel HM, Sadony V, Ravens U (1991) J Chromatogr 568:105

    CAS  PubMed  Google Scholar 

  262. Quinlan GJ, Lamb NJ, Tilley R, Evans TW, Gutteridge JM (1997) Am J Respir Crit Care Med 155:479

    CAS  PubMed  Google Scholar 

  263. Pesonen EJ, Linder N, Raivio KO, Sarnesto A, Lapatto R, Hockerstedt K, Makisalo H, Andersson S (1998) Gastroenterology 114:1009

    CAS  PubMed  Google Scholar 

  264. Koppenol WH (1998) Free Radic Biol Med 25:385

    CAS  PubMed  Google Scholar 

  265. Stirpe F, Della Corte E (1969) J Biol Chem 244:3855

    CAS  PubMed  Google Scholar 

  266. Waud WR, Rajagopalan KV (1976) Arch Biochem Biophys 172:354

    CAS  PubMed  Google Scholar 

  267. Waud WR, Rajagopalan KV (1976) Arch Biochem Biophys 172:365

    CAS  PubMed  Google Scholar 

  268. Roy RS, McCord JM (1982) Fed Proc 41:767

    Google Scholar 

  269. Engerson TD, McKelvey TG, Rhyne DB, Boggio EB, Snyder SJ, Jones HP (1987) J Clin Invest 79:1564

    PubMed Central  CAS  PubMed  Google Scholar 

  270. Parks DA, Williams TK, Beckman JS (1988) Am J Physiol 254:G768

    CAS  PubMed  Google Scholar 

  271. Frederiks WM, Bosch KS (1996) Hepatology 24:1179

    CAS  PubMed  Google Scholar 

  272. Lundberg JO, Weitzberg E (2005) Arterioscler Thromb Vasc Biol 25:915

    CAS  PubMed  Google Scholar 

  273. Alef MJ, Vallabhaneni R, Carchman E, Morris SM Jr, Shiva S, Wang Y, Kelley EE, Tarpey MM, Gladwin MT, Tzeng E, Zuckerbraun BS (2011) J Clin Invest 121:1646

    PubMed Central  PubMed  Google Scholar 

  274. Pickerodt PA, Emery MJ, Zarndt R, Martin W, Francis RC, Boemke W, Swenson ER (2012) Anesthesiology 117:592

    CAS  PubMed  Google Scholar 

  275. Samal AA, Honavar J, Brandon A, Bradley KM, Doran S, Liu Y, Dunaway C, Steele C, Postlethwait EM, Squadrito GL, Fanucchi MV, Matalon S, Patel RP (2012) Free Radic Biol Med 53:1431

    PubMed Central  CAS  PubMed  Google Scholar 

  276. Sugimoto R, Okamoto T, Nakao A, Zhan J, Wang Y, Kohmoto J, Tokita D, Farver CF, Tarpey MM, Billiar TR, Gladwin MT, McCurry KR (2012) Am J Transplant 12:2938

    CAS  PubMed  Google Scholar 

  277. Jacobson KB, Kaplan NO (1957) J Biol Chem 226:603

    CAS  PubMed  Google Scholar 

  278. Lowry OH, Passonneau JV, Schulz DW, Rock MK (1961) J Biol Chem 236:2746

    CAS  PubMed  Google Scholar 

  279. Stubbs M, Veech RL, Krebs HA (1972) Biochem J 126:59

    PubMed Central  CAS  PubMed  Google Scholar 

  280. Crow K (1983) Trends Biochem Sci 8:310

    Google Scholar 

  281. Harris CM, Massey V (1997) J Biol Chem 272:28335

    CAS  PubMed  Google Scholar 

  282. Terada LS, Dormish JJ, Shanley PF, Leff JA, Anderson BO, Repine JE (1992) Am J Physiol 263:L394

    CAS  PubMed  Google Scholar 

  283. Cantu-Medellin N, Kelley EE (2013) Redox Biol 1:353

    PubMed Central  CAS  PubMed  Google Scholar 

  284. Havemeyer A, Bittner F, Wollers S, Mendel R, Kunze T, Clement B (2006) J Biol Chem 281:34796

    CAS  PubMed  Google Scholar 

  285. Havemeyer A, Grunewald S, Wahl B, Bittner F, Mendel R, Erdelyi P, Fischer J, Clement B (2010) Drug Metab Dispos 38:1917

    CAS  PubMed  Google Scholar 

  286. Wahl B, Reichmann D, Niks D, Krompholz N, Havemeyer A, Clement B, Messerschmidt T, Rothkegel M, Biester H, Hille R, Mendel R, Bittner F (2010) J Biol Chem 285:37847

    PubMed Central  CAS  PubMed  Google Scholar 

  287. Kotthaus J, Wahl B, Havemeyer A, Kotthaus J, Schade D, Garbe-Schoenberg D, Mende R, Bittner F, Clement B (2011) Biochem J 433:383

    CAS  PubMed  Google Scholar 

  288. Klein JM, Busch JD, Potting C, Baker MJ, Langer T, Schwarz G (2012) J Biol Chem 287:42795

    PubMed Central  CAS  PubMed  Google Scholar 

  289. Gruenewald S, Wahl B, Bittner F, Hungeling H, Kanzow S, Kotthaus J, Schwering U, Mendel R, Clement B (2008) J Med Chem 51:8173

    CAS  PubMed  Google Scholar 

  290. Havemeyer A, Lang J, Clement B (2011) Drug Metab Rev 43:524

    CAS  PubMed  Google Scholar 

  291. Plitzko B, Ott G, Reichmann D, Henderson CJ, Wolf CR, Mendel R, Bittner F, Clement B, Havemeyer A (2013) J Biol Chem 288:20228

    PubMed Central  CAS  PubMed  Google Scholar 

  292. Froriep D, Clement B, Bittner F, Mendel R, Reichmann D, Schmalix W, Havemeyer A (2013) Xenobiotica 43:780

    CAS  PubMed  Google Scholar 

  293. Krompholz N, Krischkowski C, Reichmann D, Garbe-Schönberg D, Mendel R, Bittner F, Clement B, Havemeyer A (2012) Chem Res Toxicol 25:2443

    CAS  PubMed  Google Scholar 

  294. Mikula M, Rubel T, Karczmarski J, Goryca K, Dadlez M, Ostrowski J (2011) Funct Integr Genomics 11:215

    CAS  Google Scholar 

  295. Neve EPA, Nordling A, Andersson TB, Hellman U, Diczfalusy U, Johansson I, Ingelman-Sundberg M (2012) J Biol Chem 287:6307–6317

    PubMed Central  CAS  PubMed  Google Scholar 

  296. Sparacino-Watkins CE, Tejero J, Sun B, Gauthier MC, Thomas J, Ragireddy V, Merchant BA, Wang J, Azarov I, Basu P, Gladwin MT (2014) J Biol Chem 289:10345

    CAS  PubMed  Google Scholar 

  297. Garrett RM, Rajagopalan KV (1996) J Biol Chem 271:7387

    CAS  PubMed  Google Scholar 

  298. Griffith OW (1987) Methods Enzymol 143:366

    CAS  PubMed  Google Scholar 

  299. Johnson JL (2003) Prenat Diagn 23:6

    CAS  PubMed  Google Scholar 

  300. Sass JO, Gunduz A, Funayama CAR, Korkmaz B, Pinto KGD, Tuysuz B, Santos LY, Taskiran E, Turcato MF, Lam C-W, Reiss J, Walter M, Yalcinkaya C, Camelo JS (2010) Brain Dev 32:544

    PubMed  Google Scholar 

  301. Carmi-Nawi N, Malinger G, Mandel H, Ichida K, Lerman-Sagie T, Lev D (2011) J Child Neurol 26:460

    PubMed  Google Scholar 

  302. Vijayakumar K, Gunny R, Grunewald S, Carr L, Chong KW, DeVile C, Robinson R, McSweeney N, Prabhakar P (2011) Pediatr Neurol 45:246

    PubMed  Google Scholar 

  303. Cohen HJ, Becher-Lange S, Kessler DL, Rajagopalan KV (1972) J Biol Chem 247:7759

    CAS  PubMed  Google Scholar 

  304. Kisker C, Schindelin H, Pacheco A, Wehbi WA, Garrett RM, Rajagopalan KV, Enemark JH, Rees DC (1997) Cell 91:973

    CAS  PubMed  Google Scholar 

  305. Pacheco A, Hazzard JT, Tollin G, Enemark JH (1999) J Biol Inorg Chem 4:390

    CAS  PubMed  Google Scholar 

  306. Feng CJ, Kedia RV, Hazzard JT, Hurley JK, Tollin G, Enemark JH (2002) Biochemistry 41:5816

    CAS  PubMed  Google Scholar 

  307. Johnson-Winters K, Nordstrom AR, Emesh S, Astashkin AV, Rajapakshe A, Berry RE, Tollin G, Enemark JH (2010) Biochemistry 49:1290

    PubMed Central  CAS  PubMed  Google Scholar 

  308. Southerland WM, Rajagopalan KV (1978) J Biol Chem 253:8753

    CAS  PubMed  Google Scholar 

  309. Southerland WM, Winge DR, Rajagopalan KV (1978) J Biol Chem 253:8747

    CAS  PubMed  Google Scholar 

  310. Hille R (1994) Biochim Biophys Acta 1184:143

    CAS  PubMed  Google Scholar 

  311. Brody MS, Hille R (1995) Biochim Biophys Acta 1253:133

    PubMed  Google Scholar 

  312. Brody MS, Hille R (1999) Biochemistry 38:6668

    CAS  PubMed  Google Scholar 

  313. Peariso K, McNaughton RL, Kirk ML (2002) J Am Chem Soc 124:9006

    CAS  PubMed  Google Scholar 

  314. Wilson HL, Rajagopalan KV (2004) J Biol Chem 279:15105

    CAS  PubMed  Google Scholar 

  315. Bailey S, Rapson T, Winters-Johnson K, Astashkin AV, Enemark JH, Kappler U (2009) J Biol Chem 284:2053

    PubMed Central  CAS  PubMed  Google Scholar 

  316. Wang J, Krizowski S, Fischer K, Niks D, Tejero J, Sparacino-Watkins C, Wang L, Ragireddy P, Frizzell S, Kelley EE, Zhang Y, Basu P, Hille R, Schwarz G, Gladwin MT (2014) Antioxid Redox Signal. doi:10.1089/ars.2013.5397

    Google Scholar 

  317. Cueto M, Herandez-Perers O, Martin R, Bentura ML, Rodrigo J, Lamas S, Golvano MP (1996) FEBS Lett 398:159

    CAS  PubMed  Google Scholar 

  318. Leshem TY, Haramaty E (1996) J Plant Physiol 148:258

    CAS  Google Scholar 

  319. Leshem YY, Kuiper PJ (1996) Biol Plant 38:1

    Google Scholar 

  320. Noritake T, Kawakita K, Doke N (1996) Plant Cell Physiol 37:113

    CAS  Google Scholar 

  321. Ninnemann H, Maier J (1996) Photochem Photobiol 64:393

    CAS  PubMed  Google Scholar 

  322. Delledonne M, Xia Y, Dixon RA, Lamb C (1998) Nature 394:585

    CAS  PubMed  Google Scholar 

  323. Durner J, Wendehenne D, Klessig DF (1998) Proc Natl Acad Sci USA 95:10328

    PubMed Central  CAS  PubMed  Google Scholar 

  324. Mathieu C, Moreau S, Frendo P, Puppo A, Davies MJ (1998) Free Radic Biol Med 24:1242

    CAS  PubMed  Google Scholar 

  325. Beligni MV, Lamattina L (2000) Planta 210:215

    CAS  PubMed  Google Scholar 

  326. Clarke A, Desikan R, Hurst RD, Hancock JT, Neill SJ (2000) Plant J 24:667

    CAS  PubMed  Google Scholar 

  327. Foissner I, Wendehenne D, Langebartels C, Durner J (2000) Plant J 23:817

    CAS  PubMed  Google Scholar 

  328. Klessig DF, Durner J, Noad R (2000) Proc Natl Acad Sci USA 97:8849

    PubMed Central  CAS  PubMed  Google Scholar 

  329. Beligni MV, Lamattina L (2001) Plant, Cell Environ 24:267

    CAS  Google Scholar 

  330. Delledonne M, Zeier J, Marocco A, Lamb C (2001) Proc Natl Acad Sci USA 98:13454

    PubMed Central  CAS  PubMed  Google Scholar 

  331. Garcia-Mata C, Lamattina L (2001) Plant Physiol 126:1196

    CAS  PubMed  Google Scholar 

  332. Tun NN, Holk A, Scherer GF (2001) FEBS Lett 509:174

    CAS  PubMed  Google Scholar 

  333. Wendehenne D, Pugin A, Klessig DF, Durner J (2001) Trends Plant Sci 6:177

    CAS  PubMed  Google Scholar 

  334. Yamasaki H, Shimoji H, Ohshiro Y, Sakihama Y (2001) Nitric Oxide 5:261

    CAS  PubMed  Google Scholar 

  335. Beligni MV, Fath A, Bethke PC, Lamattina L, Jones RL (2002) Plant Physiol 129:1642

    PubMed Central  CAS  PubMed  Google Scholar 

  336. Desikan R, Griffiths R, Hancock J, Neill S (2002) Proc Natl Acad Sci USA 99:16314

    PubMed Central  CAS  PubMed  Google Scholar 

  337. Garcia-Mata C, Lamattina L (2002) Plant Physiol 128:790

    PubMed Central  CAS  PubMed  Google Scholar 

  338. Graziano M, Beligni MV, Lamattina L (2002) Plant Physiol 130:1852

    PubMed Central  CAS  PubMed  Google Scholar 

  339. Neill SJ, Desikan R, Clarke A, Hancock JT (2002) Plant Physiol 128:13

    PubMed Central  CAS  PubMed  Google Scholar 

  340. Neill SJ, Desikan R, Clarke A, Hurst RD, Hancock JT (2002) J Exp Bot 53:1237

    CAS  PubMed  Google Scholar 

  341. Rockel P, Strube F, Rockel A, Wildt J, Kaiser WM (2002) J Exp Bot 53:103

    CAS  PubMed  Google Scholar 

  342. Gould KS, Lamotte O, Klinguer A, Pugin A, Wendehenne D (2003) Free Radic Res 37:38

    Google Scholar 

  343. Hu X, Neill SJ, Cai W, Tang Z (2003) Funct Plant Biol 30:901

    CAS  Google Scholar 

  344. Lamattina L, Garcia-Mata C, Graziano M, Pagnussat G (2003) Annu Rev Plant Biol 54:109

    CAS  PubMed  Google Scholar 

  345. Neill SJ, Desikan R, Hancock JT (2003) New Phytol 159:11

    CAS  Google Scholar 

  346. Desikan R, Cheung MK, Bright J, Henson D, Hancock JT, Neill S (2004) J Exp Bot 55:205

    CAS  PubMed  Google Scholar 

  347. He Y, Tang RH, Hao Y, Stevens RD, Cook CW, Ahn SM, Jing L, Yang Z, Chen L, Guo F, Fiorani F, Jackson RB, Crawford NM, Pei ZM (2004) Science 305:1968

    CAS  PubMed  Google Scholar 

  348. Huang X, Stettmaier K, Michel C, Hutzler P, Mueller MJ, Durner J (2004) Planta 218:938

    CAS  PubMed  Google Scholar 

  349. Parani M, Rudrabhatla S, Myers R, Weirich H, Smith B, Leaman DW, Goldman SL (2004) Plant Biotechnol J 2:359

    CAS  PubMed  Google Scholar 

  350. Romero-Puertas MC, Perazzolli M, Zago ED, Delledonne M (2004) Cell Microbiol 6:795

    CAS  PubMed  Google Scholar 

  351. Wang JW, Wu JY (2004) Nitric Oxide 11:298

    CAS  PubMed  Google Scholar 

  352. Wendehenne D, Durner J, Klessig DF (2004) Curr Opin Plant Biol 7:449

    CAS  PubMed  Google Scholar 

  353. Zhao MG, Tian QY, Zhang WH (2007) Plant Physiol 144:206

    PubMed Central  CAS  PubMed  Google Scholar 

  354. Hong JK, Yun BW, Kang JG, Raja MU, Kwon E, Sorhagen K, Chu C, Wand Y, Loake GJ (2008) J Exp Bot 59:147

    CAS  PubMed  Google Scholar 

  355. Neill S, Bright J, Desikan R, Hancock J, Harrison J, Wilson I (2008) J Exp Bot 59:25

    CAS  PubMed  Google Scholar 

  356. Wilson ID, Neill SJ, Hancock JT (2008) Plant Cell Environ 31:622

    CAS  PubMed  Google Scholar 

  357. Zhao MG, Chen L, Zhang LL, Zhang WH (2009) Plant Physiol 151:755

    PubMed Central  CAS  PubMed  Google Scholar 

  358. Tun NN, Santa-Catarina C, Begum T, Silveira V, Handro W, Floh EIS, Scherer GFE (2006) Plant Cell Physiol 47:346

    CAS  PubMed  Google Scholar 

  359. Yamasaki H, Cohen MF (2006) Trends Plant Sci 11:522

    CAS  PubMed  Google Scholar 

  360. Rumer S, Gupta KJ, Kaiser WM (2009) J Exp Bot 60:2065

    PubMed Central  PubMed  Google Scholar 

  361. Barroso JB, Corpas FJ, Carreras A, Sandalio LM, Valderrama R, Palma JM, Lupianezi JA, del Rio LA (1999) J Biol Chem 274:36729

    CAS  PubMed  Google Scholar 

  362. Del Rio LA, Corpas FJ, Sandalio LM, Palma JM, Gomez M, Barroso JB (2002) J Exp Bot 53:1255

    PubMed  Google Scholar 

  363. Corpas FJ, Barroso JB, Carreras A (2004) Plant Physiol 136:2722

    PubMed Central  CAS  PubMed  Google Scholar 

  364. del Rio LA, Corpas FJ, Barroso JB (2004) Phytochemistry 65:783

    PubMed  Google Scholar 

  365. Corpas FJ, Barroso JB, Carreras A, Valderrama R, Palma JM, Leon AM, Sandalio LM, Rio LA (2006) Planta 224:246

    CAS  PubMed  Google Scholar 

  366. Guo FQ, Crawford NM (2005) Plant Cell 17:3436

    PubMed Central  CAS  PubMed  Google Scholar 

  367. Gas E, Flores-Perez U, Sauret-Gueto S, Rodriguez-Concepcion M (2009) Plant Cell 21:18

    PubMed Central  CAS  PubMed  Google Scholar 

  368. Del Rio LA (2010) Arch Biochem Biophys 506:1

    PubMed  Google Scholar 

  369. Simontacchi M, Jasid S, Puntarulo S (2004) Plant Sci 167:839

    CAS  Google Scholar 

  370. Gupta KJ, Stoimenova M, Kaiser WM (2005) J Exp Bot 56:2601

    CAS  PubMed  Google Scholar 

  371. Ferrari TE, Varner JE (1971) Plant Physiol 47:790

    PubMed Central  CAS  PubMed  Google Scholar 

  372. Dry I, Wallace W, Nicholas DJ (1981) Planta 152:234

    CAS  PubMed  Google Scholar 

  373. Wellbrun AR (1990) New Phytol 115:395

    Google Scholar 

  374. Kaiser WM, Brendle-Behnisch E (1995) Planta 196:1

    CAS  Google Scholar 

  375. Botrel A, Magne C, Kaiser WM (1996) Plant Physiol Biochem 34:645

    CAS  Google Scholar 

  376. Crawford NM, Smith M, Bellissimo D, Davis RW (1988) Proc Natl Acad Sci USA 85:5006

    PubMed Central  CAS  PubMed  Google Scholar 

  377. Solomonson LP, Barber MJ (1990) Annu Rev Plant Physiol Plant Mol Biol 41:225

    CAS  Google Scholar 

  378. Campbell WH (1999) Annu Rev Plant Physiol Plant Mol Biol 50:277

    CAS  PubMed  Google Scholar 

  379. Campbell WH (2001) Cell Mol Life Sci 58:194

    CAS  PubMed  Google Scholar 

  380. Solomonson LP, Barber MJ (1990) Annu Rev Plant Mol Biol 41:225

    CAS  Google Scholar 

  381. Huber SC, Bachmann M, Huber JL (1996) Trends Plant Sci 1:432

    Google Scholar 

  382. Campbell EH (1999) Annu Rev Plant Mol Biol 50:277

    CAS  Google Scholar 

  383. Kaiser WM, Weiner H, Huber SC (1999) Physiol Plant 105

  384. Kelker HC, Filner P (1971) Biochim Biophys Acta 252:69

    CAS  PubMed  Google Scholar 

  385. Gutteridge S, Bray RC, Notton BA, Fido RJ, Hewitt EJ (1983) Biochem J 213:137

    PubMed Central  CAS  PubMed  Google Scholar 

  386. Cramer SP, Solomonson LP, Adams MWW, Mortenson LE (1984) J Am Chem Soc 106:1467

    CAS  Google Scholar 

  387. Solomonson LP, Barber MJ, Howard WD, Johnson JL, Rajagopalan KV (1984) J Biol Chem 259:849

    CAS  PubMed  Google Scholar 

  388. George GN, Mertens JA, Campbell WH (1999) J Am Chem Soc 121:9730

    CAS  Google Scholar 

  389. Fischer K, Barbier GG, Hecht HJ, Mendel R, Campbell WH, Schwarz G (2005) Plant Cell 17:1167

    PubMed Central  CAS  PubMed  Google Scholar 

  390. Dean JV, Harper JE (1988) Plant Physiol 88:389

    PubMed Central  CAS  PubMed  Google Scholar 

  391. Yamasaki H, Sakihama Y, Takahashi S (1999) Trends Plant Sci 4:128

    PubMed  Google Scholar 

  392. Yamasaki H, Sakihama Y (2000) FEBS Lett 468:89

    CAS  PubMed  Google Scholar 

  393. Yamasaki H (2000) Philos Trans R Soc B 355:1477

    CAS  Google Scholar 

  394. Silaghi-Dumitrescu R, Mich M, Matyas C, Cooper CE (2012) Nitric Oxide 26:27

    CAS  PubMed  Google Scholar 

  395. Huber JL, Huber SC, Campbell WH, Redinbaugh MG (1992) Arch Biochem Biophys 296:58

    CAS  PubMed  Google Scholar 

  396. Bachmann M, Shiraishi N, Campbell WH, Yoo BC, Harmon AC, Huber SC (1996) Plant Cell 8:505

    PubMed Central  CAS  PubMed  Google Scholar 

  397. Reaume AG, Clark SH, Chovnick A (1989) Genetics 123:503

    PubMed Central  CAS  PubMed  Google Scholar 

  398. Douglas P, Moorhead G, Hong Y, Morrice N, MacKintosh C (1998) Planta 206:435

    CAS  PubMed  Google Scholar 

  399. Moorhead G, Douglas P, Morrice N, Scarabel M, Aitken A, MacKintosh C (1996) Curr Biol 6:1104

    CAS  PubMed  Google Scholar 

  400. Shen W, Huber SC (2006) Plant Cell Physiol 47:764

    CAS  PubMed  Google Scholar 

  401. Lambeck I, Chi JC, Krizowski S, Mueller S, Mehlmer N, Teige M, Fischer K, Schwarz G (2010) Biochemistry 49:8177

    CAS  PubMed  Google Scholar 

  402. Lillo C, Lea US, Leydecker MT, Meyer C (2003) Plant J 35:566

    CAS  PubMed  Google Scholar 

  403. Lea US, Hoopen F, Provan F, Kaiser WM, Meyer C, Lillo C (2004) Planta 219:59

    CAS  PubMed  Google Scholar 

  404. Lillo C, Meyer C, Lea US, Provan F, Oltedal S (2004) J Exp Bot 55:1275

    CAS  PubMed  Google Scholar 

  405. Sherameti I, Sopory SK, Trebicka A, Pfannschmidt T, Oelmüller R (2002) J Biol Chem 277:46594

    CAS  PubMed  Google Scholar 

  406. Morot-Gaudry-Talarmain Y, Rockel P, Moureaux T, Quilleré I, Leydecker M, Kaiser W, Morot-Gaudry J (2002) Planta 215:708

    CAS  PubMed  Google Scholar 

  407. Planchet E, Gupta KJ, Sonoda M, Kaiser WM (2005) Plant J 41:732

    CAS  PubMed  Google Scholar 

  408. Bright J, Desikan R, Hancock JT, Weir IS, Neill SJ (2006) Plant J 45:113

    CAS  PubMed  Google Scholar 

  409. Yamamoto-Katou A, Katou S, Yoshioka H, Doke N, Kawakita K (2006) Plant Cell Physiol 47:726

    CAS  PubMed  Google Scholar 

  410. Seligman K, Saviani EE, Oliveira HC, Pinto-Maglio CA, Salgado I (2008) Plant Cell Physiol 49:1112

    CAS  PubMed  Google Scholar 

  411. Shi FM, Li YZ (2008) BMB Rep 41:79

    CAS  PubMed  Google Scholar 

  412. Ribeiro DM, Desikan R, Bright J, Confraria A, Harrison J, Hancock JT, Barros RS, Neill SJ, Wilson ID (2009) Plant Cell Environ 32:46

    CAS  PubMed  Google Scholar 

  413. Oliveira HC, Saviani EE, Oliveira JFP, Salgado I (2010) Tropical Plant Pathol 35:104

    Google Scholar 

  414. Magalhaes JR, Silva FLIM, Salgado I, Ferrarese-Filho O, Rockel P, Kaiser WM (2002) Physiol Mol Biol Plants 8:11

    Google Scholar 

  415. Sakihama Y, Nakamura S, Yamasaki H (2002) Plant Cell Physiol 43:290

    CAS  PubMed  Google Scholar 

  416. Liu Y, Wu R, Wan Q, Xie G, Bi Y (2007) Plant Cell Physiol 48:511

    CAS  PubMed  Google Scholar 

  417. Sang J, Jiang M, Lin F, Xu S, Zhang A, Tan M (2008) Integr Plant Biol 50:231

    CAS  Google Scholar 

  418. Srivastava N, Gonugunta VK, Puli MR, Raghavendra AS (2009) Planta 229:757

    CAS  PubMed  Google Scholar 

  419. Wu SJ, Qi JL, Zhang WJ, Liu SH, Xiao FH, Zhang MS, Xu GH, Zhao WG, Shi MW, Pang YJ, Shen HG, Yang YH (2009) Plant Cell Physiol 50:118

    CAS  PubMed  Google Scholar 

  420. Harper JE (1981) Plant Physiol 68:1488

    PubMed Central  CAS  PubMed  Google Scholar 

  421. Dean JV, Harper JE (1986) Plant Physiol 82:718

    PubMed Central  CAS  PubMed  Google Scholar 

  422. Wildt J, Kley D, Rockel A, Rockel P, Segschneider HJ (1997) J Geol Res 102:5919

    CAS  Google Scholar 

  423. Kaiser WM, Weiner H, Kandlbinder A, Tsai CB, Rockel P, Sonoda M, Planchet E (2002) J Exp Bot 53:875

    CAS  PubMed  Google Scholar 

  424. Dordas C, Hasinoff BB, Rivoal J, Hill RD (2004) Planta 219:66

    CAS  PubMed  Google Scholar 

  425. Meyer C, Lea US, Provan F, Kaiser WM, Lillo C (2005) Photosynth Res 83:181

    CAS  PubMed  Google Scholar 

  426. Modolo LV, Augusto O, Almeida IMG, Pinto-Maglio CAF, Oliveira HC, Seligman K, Salgado L (2006) Plant Sci 171:34

    CAS  Google Scholar 

  427. Gupta KJ, Kaiser WM (2010) Plant Cell Physiol 51:576

    CAS  PubMed  Google Scholar 

  428. Lu D, Dong J, Jin H, Sun L, Xu X, Zhou T, Zhu Y, Xu M (2011) Appl Microbiol Biotechnol 90:1073

    CAS  PubMed  Google Scholar 

  429. Galeeva EI, Trifonova TV, Ponomareva AA, Viktorova LV, Minibayeva FV (2012) Biochemistry (Moscow) 77:404

    CAS  Google Scholar 

  430. Neill S, Barros R, Bright J, Desikan R, Hancock J, Harrison J, Morris P, Ribeiro D, Wilson I (2008) J Exp Bot 59:165

    CAS  PubMed  Google Scholar 

  431. Hao F, Zhao S, Dong H, Zhang H, Sun L, Miao C (2010) J Integr Plant Biol 52:298

    CAS  PubMed  Google Scholar 

  432. Santos-Filho PR, Vitor SC, Frungillo L, Saviani EE, Oliveira HC, Salgado I (2012) Plant Cell Physiol 53:1607

    CAS  PubMed  Google Scholar 

  433. Yamamoto A, Katou S, Yoshioka H, Doke N, Kawakita K (2003) J Gen Plant Pathol 69:218

    CAS  Google Scholar 

  434. Miller AJ, Smith SJ (1996) J Exp Bot 47:843

    CAS  Google Scholar 

  435. Kaise WN, Huber SC (2001) J Exp Bot 52:1981

    Google Scholar 

  436. Garcia-Novo F, Crawford RMM (1973) New Phytol 72:1031

    CAS  Google Scholar 

  437. Botrel A, Kaiser WM (1997) Planta 201:496

    CAS  PubMed  Google Scholar 

  438. Kaiser WM, Weiner H, Huber SC (1999) Physiol Plant 105:385

    CAS  Google Scholar 

  439. Stohr C, Mack G (2001) J Exp Bot 52:1283

    CAS  PubMed  Google Scholar 

  440. Klok EJ, Wilson IW, Wilson D, Chapman SC, Ewing RM, Somerville SC, Peacock WJ, Dolferus R, Dennis ES (2002) Plant Cell 14:2481

    PubMed Central  CAS  PubMed  Google Scholar 

  441. Stoimenova M, Libourel IGL, Ratcliff RG, Kaiser WM (2003) Plant Soil 253:155

    CAS  Google Scholar 

  442. Lager IDA, Andreasson O, Dunbar TL, Andreasson E, Escobar MA, Rasmusson AG (2010) Plant Cell Environ 33:1513

    PubMed Central  CAS  PubMed  Google Scholar 

  443. Kruger NJ, von Schaewen A (2003) Curr Opin Plant Biol 6:236

    CAS  PubMed  Google Scholar 

  444. Shingle R, Roh MH, McCarty RE (1996) Plant Phyisiol 112:1375

    Google Scholar 

  445. Crawford NM (1995) Plant Cell 7:859

    PubMed Central  CAS  PubMed  Google Scholar 

  446. Klepper LA (1975) Weed Sci 23:188

    CAS  Google Scholar 

  447. Klepper LA (1976) Weed Sci 24:533

    CAS  Google Scholar 

  448. Vaucheret H, Kronenberger J, Lepingle A, Vilaine F, Boutin JP, Caboche M (1992) Plant J 2:559

    CAS  PubMed  Google Scholar 

  449. Goshima N, Mukai T, Suemori M, Takahashi M, Caboche M, Morikawa H (1999) Plant J 19:75

    CAS  PubMed  Google Scholar 

  450. Wang BL, Tang XY, Cheng LY, Zhang AZ, Zhang WH, Zhang FS, Liu JQ, Cao Y, Allan DL, Vance CP, Shen JB (2010) New Phytol 187:1112

    CAS  PubMed  Google Scholar 

  451. Xiong J, Fu G, Yang Y, Zhu C, Tao L (2012) J Exp Bot 63:33

    CAS  PubMed  Google Scholar 

  452. Hesberg C, Haensch R, Mendel R, Bittner F (2004) J Biol Chem 279:13547

    CAS  PubMed  Google Scholar 

  453. Sandalio LM, Fernandez VM, Ruperez FL, del Rio LA (1988) Plant Physiol 87:1

    PubMed Central  CAS  PubMed  Google Scholar 

  454. Corpas FJ, Colina C, Sanchez-Rasero F, Rio LA (1997) J Plant Physiol 151:246

    CAS  Google Scholar 

  455. Corpas FJ, Palma JM, Sandalio LM, Valderrama R, Barroso JB, del Rio LA (2008) J Plant Physiol 165:1319

    CAS  PubMed  Google Scholar 

  456. Planchet E, Kaiser WM (2006) Plant Signal Behav 1:46

    PubMed Central  PubMed  Google Scholar 

  457. Zumft WG (1997) Microbiol Mol Biol Rev 61:533

    PubMed Central  CAS  PubMed  Google Scholar 

  458. Marshall HE, Merchant K, Stamler JS (2000) FASEB J 14:1889

    CAS  PubMed  Google Scholar 

  459. Nakano MM (2002) J Bacteriol 184:1783

    PubMed Central  CAS  PubMed  Google Scholar 

  460. Mukhopadhyay P, Zheng M, Bedzyk LA, LaRossa RA, Storz G (2004) Proc Natl Acad Sci USA 101:745

    PubMed Central  CAS  PubMed  Google Scholar 

  461. Gusarov I, Nudler E (2005) Proc Natl Acad Sci USA 102:13855

    PubMed Central  CAS  PubMed  Google Scholar 

  462. Hochgrafe F, Wolf C, Fuchs S, Liebeke M, Lalk M, Engelmann S, Hecker M (2008) J Bacteriol 190:4997

    PubMed Central  PubMed  Google Scholar 

  463. Shatalin K, Gusarov I, Avetissova E, Shatalina Y, McQuade LE, Lippard SJ, Nudler E (2008) Proc Natl Acad Sci USA 105:1009

    PubMed Central  CAS  PubMed  Google Scholar 

  464. Gusarov I, Shatalin K, Starodubtseva M, Nudler E (2009) Science 325:1380

    PubMed Central  CAS  PubMed  Google Scholar 

  465. Patel BA, Moreau M, Widom J, Chen H, Yin L, Hua Y, Crane BR (2009) Proc Natl Acad Sci USA 106:18183

    PubMed Central  CAS  PubMed  Google Scholar 

  466. Buddha MR, Tao T, Parry RJ, Crane BR (2004) J Biol Chem 279:49567

    CAS  PubMed  Google Scholar 

  467. Kers JA, Wach MJ, Krasnoff SB, Widom J, Cameron KD, Bukhalid RA, Gibson DM, Crane BR, Loria R (2004) Nature 429:79

    CAS  PubMed  Google Scholar 

  468. Wach MJ, Kers JA, Krasnoff SB, Loria R, Gibson DM (2005) Nitric Oxide 12:46

    CAS  PubMed  Google Scholar 

  469. Johnson EG, Sparks JP, Dzikovski B, Crane BR, Gibson DM, Loria R (2008) Chem Biol 15:43

    CAS  PubMed  Google Scholar 

  470. Adak S, Aulak K, Stuehr DJ (2002) J Biol Chem 277:16167

    CAS  PubMed  Google Scholar 

  471. Adak S, Bilwes AM, Panda K, Hosfield D, Aulak KS, McDonald JF, Tainer JA, Getzoff ED, Crane BR, Stuehr DJ (2002) Proc Natl Acad Sci USA 99:107

    PubMed Central  CAS  PubMed  Google Scholar 

  472. Sudhamsu J, Crane BR (2006) J Biol Chem 281:9623

    CAS  PubMed  Google Scholar 

  473. Gusarov I, Starodubtseva M, Wang Z, McQuade L, Lippard SJ, Stuehr DJ, Nudler E (2008) J Biol Chem 283:13140

    PubMed Central  CAS  PubMed  Google Scholar 

  474. Schneiker S, Perlova O, Kaiser O, Gerth K, Alici A, Altmeyer MO, Bartels D, Bekel T, Beyer S, Bode E, Bode HB, Bolten CJ, Choudhuri JV, Doss S, Elnakady YA, Frank B, Gaigalat L, Goesmann A, Groeger C, Gross F, Jelsbak L, Jelsbak L, Kalinowski J, Kegler C, Knauber T, Konietzny S, Kopp M, Krause L, Krug D, Linke B, Mahmud T, Martinez-Arias R, McHardy AC, Merai M, Meyer F, Mormann S, Muñoz-Dorado J, Perez J, Pradella S, Rachid S, Raddatz G, Rosenau F, Rückert C, Sasse F, Scharfe M, Schuster SC, Suen G, Treuner-Lange A, Velicer GJ, Vorhölter FJ, Weissman KJ, Welch RD, Wenzel SC, Whitworth DE, Wilhelm S, Wittmann C, Blöcker H, Pühler A, Müller R (2007) Nat Biotechnol 25:1281

    CAS  PubMed  Google Scholar 

  475. Reece SY, Woodward JJ, Marletta MA (2009) Biochemistry 48:5483

    CAS  PubMed  Google Scholar 

  476. Sudhamsu J, Crane BR (2009) Trends Microbiol 17:212

    CAS  PubMed  Google Scholar 

  477. Chen Y, Rosazza JP (1994) Biochem Biophys Res Commun 203:1251

    CAS  PubMed  Google Scholar 

  478. Chen YJ, Rosazza JPN (1995) J Bacteriol 177:5122

    PubMed Central  CAS  PubMed  Google Scholar 

  479. Stachura J, Konturek JW, Karczewska A, Domschke W, Popiela T, Konturek SJ (1996) J Physiol Pharmacol 47:131

    CAS  PubMed  Google Scholar 

  480. Choi WS, Chang MS, Han JW, Hong SY, Lee HW (1997) Biochem Biophys Res Commun 237:554

    CAS  PubMed  Google Scholar 

  481. Bird LE, Ren J, Zhang J, Foxwell N, Hawkins AR, Charles IG, Stammers DK (2002) Structure 10:168

    Google Scholar 

  482. Pant K, Bilwes AM, Adak S, Stuehr DJ, Crane BR (2002) Biochemistry 41:11071

    CAS  PubMed  Google Scholar 

  483. Wang ZQ, Lawson RJ, Buddha MR, Wei CC, Crane BR, Munro AW, Stuehr DJ (2007) J Biol Chem 282:2196

    CAS  PubMed  Google Scholar 

  484. Crane BR (2008) Biochem Soc Trans 36:1149

    CAS  PubMed  Google Scholar 

  485. Agapie T, Suseno S, Woodward JJ, Stoll S, Britt RD, Marletta MA (2009) Proc Natl Acad Sci USA 106:16221

    PubMed Central  CAS  PubMed  Google Scholar 

  486. Smith MS (1983) Appl Environ Microbiol 45:1545

    PubMed Central  CAS  PubMed  Google Scholar 

  487. Calmels S, Ohshima H, Bartsch H (1988) J Gen Microbiol 134:221

    CAS  PubMed  Google Scholar 

  488. Ji XB, Hollocher TC (1988) Appl Environ Microbiol 54:1791

    PubMed Central  CAS  PubMed  Google Scholar 

  489. Ji XB, Hollocher TC (1988) Biochem Biophys Res Commun 157:106

    CAS  PubMed  Google Scholar 

  490. Metheringham R, Cole JA (1997) Microbiology 143:2647

    CAS  PubMed  Google Scholar 

  491. Corker H, Poole RK (2003) J Biol Chem 278:31584

    CAS  PubMed  Google Scholar 

  492. Tang X, Chen J, Wang WH, Liu TW, Zhang J, Gao YH, Pei ZM, Zheng HL (2011) Environ Pollut 159:3784

    CAS  PubMed  Google Scholar 

  493. Weiss B (2006) J Bacteriol 188:829

    PubMed Central  CAS  PubMed  Google Scholar 

  494. Coleman KJ, Cornish-Bowden A, Cole JA (1978) Biochem J 175:483

    PubMed Central  CAS  PubMed  Google Scholar 

  495. Vine CE, Cole JA (2011) Biochem Soc Trans 39:213

    CAS  PubMed  Google Scholar 

  496. Vine CE, Cole JA (2011) FEMS Microbiol Lett 325:99

    CAS  PubMed  Google Scholar 

  497. Couture M, Das T, Savard P, Ouellet Y, Wittenberg J, Wittenberg B, Rousseau D, Guertin M (2000) Eur J Biochem 267:4770

    CAS  PubMed  Google Scholar 

  498. Scott N, Lecomte J (2000) Protein Sci 9:587

    PubMed Central  CAS  PubMed  Google Scholar 

  499. Hvitved AN, Trent JT 3rd, Premer SA, Hargrove MS (2001) J Biol Chem 276:34714

    CAS  PubMed  Google Scholar 

  500. Vu B, Jones A, Lecomte J (2002) J Am Chem Soc 124:8544

    CAS  PubMed  Google Scholar 

  501. Hoy J, Kundu S, Trent JT, Ramaswamy S, Hargrove M (2004) J Biol Chem 279:16535

    CAS  PubMed  Google Scholar 

  502. Sturms R, DiSpirito AA, Hargrove MS (2011) Biochemistry 50:3873

    CAS  PubMed  Google Scholar 

  503. Richardson DJ (2000) Microbiology 146:551

    CAS  PubMed  Google Scholar 

  504. Potter L, Angove H, Richardson D, Cole J (2001) Adv Microb Physiol 45:51

    CAS  PubMed  Google Scholar 

  505. Stolz JF, Basu P (2002) Chem Bio Chem 3:198

    CAS  PubMed  Google Scholar 

  506. Bertero MG, Rothery RA, Palak M, Hou C, Lim D, Blasco F, Weiner JH, Strynadka NCJ (2003) Nat Struct Biol 10:681

    CAS  PubMed  Google Scholar 

  507. Jormakka M, Richardson D, Byrne B, Iwata S (2004) Structure 12:95

    CAS  PubMed  Google Scholar 

  508. González PG, Correia C, Moura I, Brondino CD, Moura JJG (2006) J Inorg Biochem 100:1015

    PubMed  Google Scholar 

  509. Martinez-Espinosa RM, Dridge EJ, Bonete MJ, Butt JN, Butler CS, Sargent F, Richardson DJ (2007) FEMS Microbiol Lett 276:129

    CAS  PubMed  Google Scholar 

  510. Kern M, Simon J (2009) Microbiology (SGM) 155:2784

    CAS  Google Scholar 

  511. Lowe EC, Bydder S, Hartshorne RS, Tape HLU, Dridge EJ, Debieux CM, Paszkiewicz K, Singleton I, Lewis RJ, Santini JM, Richardson DJ, Butler CS (2010) J Biol Chem 285:18433

    PubMed Central  CAS  PubMed  Google Scholar 

  512. Dobbek H (2011) Coord Chem Rev 255:1104

    CAS  Google Scholar 

  513. Kraft B, Strous M, Tegetmeyer HE (2011) J Biotechnol 155:104

    CAS  PubMed  Google Scholar 

  514. Pushie MJ, George GN (2011) Coord Chem Rev 255:1055

    CAS  Google Scholar 

  515. Grimaldi S, Schoepp-Cothenet B, Ceccaldi P, Guigliarelli B, Magalon A (2013) Biochim Biophys Acta 1827:1048

    CAS  PubMed  Google Scholar 

  516. Sparacino-Watkins C, Stolzb JF, Basu P (2014) Chem Soc Rev 43:676

    PubMed Central  CAS  PubMed  Google Scholar 

  517. Bertero MG, Rothery RA, Boroumand N, Palak M, Blasco F, Ginet N, Weiner JH, Strynadka NCJ (2005) J Biol Chem 280:14836

    CAS  PubMed  Google Scholar 

  518. Dias JM, Than ME, Humm A, Huber R, Bourenkov GP, Bartunik HD, Bursakov S, Calvete J, Caldeira J, Carneiro C, Moura JJG, Moura I, Romao MJ (1999) Structure 7:65

    CAS  PubMed  Google Scholar 

  519. Coelho C, Gonzalez PJ, Trincão J, Carvalho AL, Najmudin S, Hettman T, Dieckman S, Moura JJG, Moura I, Romão MJ (2007) Acta Cryst Sect F 63:516

    CAS  Google Scholar 

  520. Najmudin S, Gonzalez PJ, Trincão J, Coelho C, Mukhopadhyay A, Romao CC, Moura I, Moura JJG, Brondino CD, Romao MJ (2008) J Biol Inorg Chem 13:737

    CAS  PubMed  Google Scholar 

  521. Coelho C, Gonzalez PJ, Moura JJG, Moura I, Trincao J, Romao MJ (2011) J Mol Biol 408:932

    CAS  PubMed  Google Scholar 

  522. Jepson BJN, Mohan S, Clarke TA, Gates AJ, Cole JA, Butler CS, Butt JN, Hemmings AM, Richardson DJ (2007) J Biol Chem 282:6425

    CAS  PubMed  Google Scholar 

  523. Arnoux P, Sabaty M, Alric J, Frangioni B, Guigliarelli B, Adriano JM, Pignol D (2003) Nat Struct Biol 10:928

    CAS  PubMed  Google Scholar 

  524. Jepson BJN, Anderson LJ, Rubio LM, Taylor CJ, Butler CS, Flores E, Herrero A, Butt JN, Richardson DJ (2004) J Biol Chem 279:32212

    CAS  PubMed  Google Scholar 

  525. Smith MS, Zlmmerman K (1981) Soil Sci Soc Am J 45:865

    CAS  Google Scholar 

  526. Bleakley BH, Tiedje JM (1982) Appl Environ Microbiol 44:1342

    PubMed Central  CAS  PubMed  Google Scholar 

  527. Smith MS (1982) Appl Environ Microbiol 43:854

    PubMed Central  CAS  PubMed  Google Scholar 

  528. Satoh T, Hom SS, Shanmugam KT (1983) J Bacteriol 155:454

    PubMed Central  CAS  PubMed  Google Scholar 

  529. Ralt D, Wishnok JS, Fitts R, Tannenbaum SR (1988) J Bacteriol 170:359

    PubMed Central  CAS  PubMed  Google Scholar 

  530. Gilberthorpe NJ, Poole RK (2008) J Biol Chem 283:11146

    CAS  PubMed  Google Scholar 

  531. Vine CE, Purewal SK, Cole JA (2011) FEMS Microbiol Lett 325:108

    CAS  PubMed  Google Scholar 

  532. Rowley G, Hensen D, Felgate H, Arkenberg A, Appia-Ayme C, Prior K, Harrington C, Field SJ, Butt JN, Baggs E, Richardson DJ (2012) Biochem J 441:755

    CAS  PubMed  Google Scholar 

  533. Einsle O, Kroneck PMH (2004) J Biol Chem 385:875

    CAS  Google Scholar 

  534. Moura JJG, Xavier AV, Bruschi M, Le Gall J, Hall DO, Cammack R (1976) Biochem Biophys Res Commun 72:782

    CAS  PubMed  Google Scholar 

  535. Barata BA, LeGall J, Moura JJG (1993) Biochemistry 32:11559

    CAS  PubMed  Google Scholar 

  536. Romao MJ, Archer M, Moura I, Moura JJG, LeGall J, Engh R, Schneider M, Hof P, Huber R (1995) Science 270:1170

    CAS  PubMed  Google Scholar 

  537. Huber R, Hof P, Duarte RO, Moura JJG, Moura I, Liu MY, Legall J, Hille R, Archer M, Romao MJ (1996) Proc Natl Acad Sci USA 93:8846

    PubMed Central  CAS  PubMed  Google Scholar 

  538. Rebelo JM, Dias JM, Huber R, Moura JJG, Romaao MJ (2001) J Biol Inorg Chem 6:791

    CAS  PubMed  Google Scholar 

  539. Krippahl L, Palma N, Moura I, Moura JJG (2006) Eur J Inorg Chem 19:3835

    Google Scholar 

  540. Burgrnayer SJN, Stlefel EI (1985) J Chem Educ 62:943

    Google Scholar 

  541. Harlan EE, Berg JM, Holm RH (1986) J Am Chem Soc 108:6992

    CAS  Google Scholar 

  542. Stiefel EI (1973) Proc Natl Acad Sci USA 70:988

    PubMed Central  CAS  PubMed  Google Scholar 

  543. Rajapakshe A, Snyder RA, Astashkin AV, Bernardson P, Evans DJ, Young CG, Evans DH, Enemark JH (2009) Inorg Chim Acta 362:4603

    CAS  Google Scholar 

  544. Ghosh S, Dey A, Sun Y, Scholes CP, Solomon EI (2009) J Am Chem Soc 131:277

    PubMed Central  CAS  PubMed  Google Scholar 

  545. George GN, Bray RC (1988) Biochemistry 27:3603

    CAS  PubMed  Google Scholar 

  546. Wilson GL, Greenwood RJ, Pilbrow JR, Spence JT, Wedd AG (1991) J Am Chem Soc 113:6803

    CAS  Google Scholar 

  547. Doonan CJ, Rubie ND, Peariso K, Harris HH, Knottenbelt SZ, George GN, Young CC, Kirk ML (2008) J Am Chem Soc 130:55

    CAS  PubMed  Google Scholar 

  548. Cerqueira NM, Fernandes PA, Gonzalez PJ, Moura JJB, Ramos MJ (2013) Inorg Chem 52:10766

    CAS  PubMed  Google Scholar 

  549. Holm RH, Berg JM (1986) Acc Chem Res 19:363

    CAS  Google Scholar 

  550. Holm RH (1987) Chem Rev 87:1401

    CAS  Google Scholar 

  551. Holm RH (1990) Coord Chem Rev 100:183

    CAS  Google Scholar 

  552. Xiao Z, Young CG, Enemark JH, Wedd AG (1992) J Am Chem Soc 114:9194

    CAS  Google Scholar 

  553. Scbultz BE, Gbeller SF, Muetterties MC, Scott MJ, Holm RH (1993) J Am Chem Soc 115:2714

    Google Scholar 

  554. Schultz BE, Holm RH (1993) Inorg Chem 32:4244

    CAS  Google Scholar 

  555. Enemark JG, Young CG (1994) Adv Inorg Chem 40:1

    CAS  Google Scholar 

  556. Das SK, Chaudhury PK, Biswas D, Sarkar S (1994) J Am Chem Soc 116:9061

    CAS  Google Scholar 

  557. Oku H, Ueyama N, Kondo M, Nakamura A (1994) Inorg Chem 33:209

    CAS  Google Scholar 

  558. Holm RH, Kennepohl P, Solomon EI (1996) Chem Rev 96:2239

    CAS  PubMed  Google Scholar 

  559. Laughlin LJ, Young CG (1996) Inorg Chem 35:1050

    CAS  PubMed  Google Scholar 

  560. Enemark JH, Cooney JA, Wang JJ, Holm RH (2004) Chem Rev 104:1175

    CAS  PubMed  Google Scholar 

  561. Murray KN, Watson JG, Chaykin S (1966) J Biol Chem 241:4798

    CAS  PubMed  Google Scholar 

  562. Hille R, Sprecher H (1987) J Biol Chem 262:10914

    CAS  PubMed  Google Scholar 

  563. Schultz BE, Hille R, Holm RH (1995) J Am Chem Soc 117:827

    CAS  Google Scholar 

  564. Cutruzzolà F, Rinaldo S, Castiglione N, Giardina G, Pecht I, Brunori M (2009) BioEssays 31:885

    PubMed  Google Scholar 

  565. Copley SD (2012) BioEssays 34:578

    CAS  PubMed  Google Scholar 

Download references

Acknowledgments

This work was supported by projects PTDC/QUI-BIQ/100366/2008 and PEst-C/EQB/LA0006/2013 (Fundação para a Ciência e Tecnologia/MCTES, Portugal).

Author information

Authors and Affiliations

  1. UCIBIO, REQUIMTE, Departamento de Química, Faculdade de Ciências e Tecnologia, Universidade Nova de Lisboa, 2829-516, Caparica, Portugal

    Luisa B. Maia & José J. G. Moura

Authors
  1. Luisa B. Maia
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. José J. G. Moura
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Luisa B. Maia.

Additional information

Responsible Editors: José Moura and Paul Bernhardt.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Maia, L.B., Moura, J.J.G. Nitrite reduction by molybdoenzymes: a new class of nitric oxide-forming nitrite reductases. J Biol Inorg Chem 20, 403–433 (2015). https://doi.org/10.1007/s00775-014-1234-2

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00775-014-1234-2

Keywords

Search

Navigation