Abstract
There is a growing interest in using biomonitoring of tooth and bone specimens to assess human exposure to manganese (Mn). Information on historical exposure to Mn can be obtained through micro-spatial analysis of such specimens by laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS). The principal aim of this study was to compare several calibration strategies for determining Mn content in tooth and bone by LA-ICP-MS including: (a) a six-point calibration curve based on synthesized hydroxyapatite (HA) materials, and single-point calibrations based on (b) NIST SRM 1400 Bone Ash, (c) NIST SRM 1486 Bone Meal, and (d) NIST SRM 612 Trace Elements in Glass. Performance was similar between different ICP-MS platforms (quadrupole ICP-MS, dynamic reaction cell ICP-MS, and sector field ICP-MS). Data based on calibration using the 55Mn count rate were compared to that based on using the 55Mn/43Ca count rate ratio to obtain results as the Mn mass fraction. Reasonable performance was obtained by calibration using either SRM 612 or SRM 1400, in combination with the 55Mn/43Ca count rate ratio and using either the synthesized HA standards or SRM 1400 as calibrators, combined with 55Mn count rate. By contrast, calibration based on SRM 1486 resulted in a systematic low bias. While there are several options for quantifying the Mn content of tooth and bone using LA-ICP-MS, users should be aware of the potential for strong matrix effects that may affect results. Overall, determining the 55Mn/43Ca count rate ratio, rather than the mass fraction, may represent a better approach for reporting the content of Mn in tooth and bone by LA-ICP-MS.
References
Arora M, Kennedy BJ, Elhlou S, Pearson NJ, Walker DM, Bayl P, Chan SWY (2006) Spatial distribution of lead in human primary teeth as a biomarker of pre- and neonatal lead exposure. Sci Total Environ 371:55–62
Grün R, Aubert M, Joannes-Boyau R, Moncel MH (2008) High resolution analysis of uranium and thorium concentration as well as U-series isotope distributions in a Neanderthal tooth from Payre (Ardèche, France) using laser ablation ICP-MS. Geochim Cosmochim Acta 72:5278–5290
Shepherd TJ, Dirks W, Manmee C, Hodgson S, Banks DA, Averley P, Pless-Mulloli T (2012) Reconstructing the life-time lead exposure in children using dentine in deciduous teeth. Sci Total Environ 425:214–222
Castro W, Hoogewerff J, Latkoczy C, Almirall JR (2010) Application of laser ablation (LA-ICP-SF-MS) for the elemental analysis of bone and teeth samples for discrimination purposes. Forensic Sci Int 195:17–27
Uryu T, Yoshinaga J, Yanagisawa Y, Endo M, Takahashi J (2003) Analysis of lead in tooth enamel by laser ablation-inductively coupled plasma-mass spectrometry. Anal Sci 19:1413–1416
Bellis DJ, Hetter KM, Jones J, Arnarasiriwardena D, Parsons PJ (2008) Lead in teeth from lead-dosed goats: micro distribution and relationship to the cumulative lead dose. Environ Res 106:34–41
Hare D, Austin C, Doble P, Arora M (2011) Elemental bio-imaging of trace elements in teeth using laser ablation-inductively coupled plasma-mass spectrometry. J Dent 39:397–403
Arora M, Hare D, Austin C, Smith DR, Doble P (2011) Spatial distribution of manganese in enamel and coronal dentine of human primary teeth. Sci Total Environ 409:1315–1319
Charadram N, Austin C, Trimby P, Simonian M, Swain MV, Hunter N (2013) Structural analysis of reactionary dentin formed in response to polymicrobial invasion. J Struct Biol 181:207–222
Vašinová Galiová M, Nývltová Fišáková M, Kynický J, Prokeš L, Neff H, Mason AZ, Gadas P, Košler J, Kanický V (2013) Elemental mapping in fossil tooth root section of Ursus arctos by laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS). Talanta 105:235–243
Stadlbauer C, Reiter C, Patzak B, Stingeder G, Prohaska T (2007) History of individuals of the 18th/19th centuries stored in bones, teeth, and hair analyzed by LA-ICP-MS-a step in attempts to confirm the authenticity of Mozart’s skull. Anal Bioanal Chem 388:593–602
Ugarte A, Unceta N, Pécheyran C, Goicolea MA, Barrio RJ (2011) Development of matrix-matching hydroxyapatite calibration standards for quantitative multi-element LA-ICP-MS analysis: application to the dorsal spine of fish. J Anal At Spectrom 26:1421–1427
Abdullah MM, Ly AR, Goldberg WA, Clarke-Stewart KA, Dudgeon JV, Mull CG, Chan TJ, Kent EE, Mason AZ, Ericson JE (2012) Heavy metal in children’s tooth enamel: related to autism and disruptive behaviors? J Autism Dev Disord 42:929–936
Hetter KM, Bellis DJ, Geraghty C, Todd AC, Parsons PJ (2008) Development of candidate reference materials for the measurement of lead in bone. Anal Bioanal Chem 391:2011–2021
Bellis DJ, Hetter KM, Jones J, Amarasiriwardena D, Parsons PJ (2006) Calibration of laser ablation inductively coupled plasma mass spectrometry for quantitative measurements of lead in bone. J Anal At Spectrom 21:948–954
Farell J, Amarasiriwardena D, Goodman AH, Arriaza B (2013) Bioimaging of trace metals in ancient Chilean mummies and contemporary Egyptian teeth by laser ablation-inductively coupled plasma-mass spectrometry (LA-ICP-MS). Microchem J 106:340–346
Hanć A, Olszewska A, Barałkiewicz D (2013) Quantitative analysis of elements migration in human teeth with and without filling using LA-ICP-MS. Microchem J 110:61–69
Bellis DJ, Hetter KM, Verostek MF, Parsons PJ (2008) Characterization of candidate reference materials for bone lead via interlaboratory study and double isotope dilution mass spectrometry. J Anal At Spectrom 23:298–308
Takser L, Mergler D, Hellier G, Sahuquillo J, Huel G (2003) Manganese, monoamine metabolite levels at birth, and child psychomotor development. Neurotoxicology 24:667–674
Ericson JE, Crinella FM, Clarke-Stewart KA, Allhusen VD, Chan T, Robertson RT (2007) Prenatal manganese levels linked to childhood behavioral disinhibition. Neurotoxicol Teratol 29:181–187
Henn BC, Ettinger AS, Schwartz J, Téllez-Rojo MM, Lamadrid-Figueroa H, Hernández-Avila M, Schnaas L, Amarasiriwardena C, Bellinger DC, Hu H, Wright RO (2010) Early postnatal blood manganese levels and children’s neurodevelopment. Epidemiology 21:433–439
Arora M, Bradman A, Austin C, Vedar M, Holland N, Eskenazi B, Smith DR (2012) Determining fetal manganese exposure from mantle dentine of deciduous teeth. Environ Sci Technol 46:5118–5125
Gunier RB, Bradman A, Jerrett M, Smith DR, Harley KG, Austin C, Vedar M, Arora M, Eskenazi B (2013) Determinants of manganese in prenatal dentin of shed teeth from CHAMACOS children living in an agricultural community. Environ Sci Technol 47:11249–11257
NIST SRM 612 Trace Elements in Glass Certificate of Analysis (2012) NIST, Gaithersburg. http://www.nist.gov/srm. Accessed 24 July 2013
Praamsma ML, Parsons PJ (2014) Characterization of calcified reference materials for assessing the reliability of manganese determinations in teeth and bone. J Anal At Spectrom 29:1243–1251
NIST SRM 1400 Bone Ash Certificate of Analysis (1992) NIST, Gaithersburg. http://www.nist.gov/srm. Accessed 24 July 2013
NIST SRM 1486 Bone Meal Certificate of Analysis (1992) NIST, Gaithersburg. http://www.nist.gov/srm. Accessed 24 July 2013
Arnold WH, Gaengler P (2007) Quantitative analysis of the calcium and phosphorus content of developing and permanent human teeth. Ann Anat 189:183–190
Praamsma ML, Arnason JG, Parsons PJ (2011) Monitoring Mn in whole blood and urine: a comparison between electrothermal atomic absorption and inorganic mass spectrometry. J Anal At Spectrom 26:1224–1232
Longerich HP, Jackson SE, Günther D (1996) Laser ablation inductively coupled plasma mass spectrometric transient signal data acquisition and analyte concentration calculation. J Anal At Spectrom 11:899–904
Gruhl S, Witte F, Vogt J, Vogt C (2009) Determination of concentration gradients in bone tissue generated by a biologically degradable magnesium implant. J Anal At Spectrom 24:181–188
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Praamsma, M.L., Parsons, P.J. Calibration strategies for quantifying the Mn content of tooth and bone samples by LA-ICP-MS. Accred Qual Assur 21, 385–393 (2016). https://doi.org/10.1007/s00769-016-1234-8
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00769-016-1234-8