Archives of Women's Mental Health

, Volume 16, Issue 1, pp 79–81

Comorbid bipolar disorder and premenstrual dysphoric disorder: real patients, unanswered questions

Authors

    • Women’s Health Concerns Clinic, St. Joseph’s Healthcare HamiltonMcMaster University
    • Mood Disorders Program, Department of Psychiatry and Behavioural NeurosciencesMcMaster University
  • Luciano Minuzzi
    • Women’s Health Concerns Clinic, St. Joseph’s Healthcare HamiltonMcMaster University
    • Mood Disorders Program, Department of Psychiatry and Behavioural NeurosciencesMcMaster University
Short Communication

DOI: 10.1007/s00737-012-0313-z

Cite this article as:
Frey, B.N. & Minuzzi, L. Arch Womens Ment Health (2013) 16: 79. doi:10.1007/s00737-012-0313-z

Abstract

Large-scale clinical and epidemiological studies suggest a link between bipolar disorder (BD) and premenstrual dysphoric disorder (PMDD). However, smaller studies using prospective charting failed to find this association. Here, we report three cases of individuals with BD and comorbid PMDD who responded successfully to adjunctive contraceptive agents in the management of their severe premenstrual symptoms. While controlled trials investigating pharmacological and non-pharmacological treatments are awaited, adjunctive treatment of contraceptive agents and mood stabilizers may be an option in the treatment of comorbid BD and PMDD.

Keywords

Bipolar disorder Contraceptives Premenstrual dysphoric disorder Premenstrual syndrome Treatment

Copyright information

© Springer-Verlag Wien 2012