, Volume 39, Issue 1, pp 45-57
Date: 28 Mar 2010

Nucleobase-containing peptides: an overview of their characteristic features and applications

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Abstract

Reports on nucleobase-containing chiral peptides (both natural and artificial) and achiral pseudopeptides are reviewed. Their synthesis, structural features, DNA and RNA-binding ability, as well as some other interesting applications which make them promising diagnostic/therapeutic agents of great importance in many areas of biology and therapy are taken into critical consideration.