Amino Acids

, Volume 39, Issue 1, pp 45–57

Nucleobase-containing peptides: an overview of their characteristic features and applications

  • Giovanni N. Roviello
  • Ettore Benedetti
  • Carlo Pedone
  • Enrico M. Bucci
Minireview Article

DOI: 10.1007/s00726-010-0567-6

Cite this article as:
Roviello, G.N., Benedetti, E., Pedone, C. et al. Amino Acids (2010) 39: 45. doi:10.1007/s00726-010-0567-6

Abstract

Reports on nucleobase-containing chiral peptides (both natural and artificial) and achiral pseudopeptides are reviewed. Their synthesis, structural features, DNA and RNA-binding ability, as well as some other interesting applications which make them promising diagnostic/therapeutic agents of great importance in many areas of biology and therapy are taken into critical consideration.

Keywords

NucleobasePeptideNucleopeptideNucleic acid

Copyright information

© Springer-Verlag 2010

Authors and Affiliations

  • Giovanni N. Roviello
    • 1
  • Ettore Benedetti
    • 2
  • Carlo Pedone
    • 1
  • Enrico M. Bucci
    • 1
  1. 1.Istituto di Biostrutture e BioimmaginiConsiglio Nazionale delle RicercheNaplesItaly
  2. 2.Department of Scienze Biologiche sez. BiostruttureUniversità degli Studi di Napoli ‘Federico II’NaplesItaly