Amino Acids

, Volume 39, Issue 1, pp 45–57

Nucleobase-containing peptides: an overview of their characteristic features and applications

Authors

  • Giovanni N. Roviello
    • Istituto di Biostrutture e BioimmaginiConsiglio Nazionale delle Ricerche
    • Department of Scienze Biologiche sez. BiostruttureUniversità degli Studi di Napoli ‘Federico II’
  • Carlo Pedone
    • Istituto di Biostrutture e BioimmaginiConsiglio Nazionale delle Ricerche
  • Enrico M. Bucci
    • Istituto di Biostrutture e BioimmaginiConsiglio Nazionale delle Ricerche
Minireview Article

DOI: 10.1007/s00726-010-0567-6

Cite this article as:
Roviello, G.N., Benedetti, E., Pedone, C. et al. Amino Acids (2010) 39: 45. doi:10.1007/s00726-010-0567-6

Abstract

Reports on nucleobase-containing chiral peptides (both natural and artificial) and achiral pseudopeptides are reviewed. Their synthesis, structural features, DNA and RNA-binding ability, as well as some other interesting applications which make them promising diagnostic/therapeutic agents of great importance in many areas of biology and therapy are taken into critical consideration.

Keywords

Nucleobase Peptide Nucleopeptide Nucleic acid

Copyright information

© Springer-Verlag 2010